DAB2IP
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Homo sapiens |
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DAB2IP is differentially expressed in 140 experiments: 83 organism parts: bone marrow, cerebellum, ... (81 more);, 79 disease states: normal, prostate carcinoma, ... (77 more);, 49 cell types 361 cell lines 16 compound treatments and 48 other conditions. |
| Synonyms |
AIP1, AF9Q34, KIAA1743, DIP1/2 |
| Orthologs |
Dab2ip
(Mus musculus)
DAB2IP
(Gallus gallus)
Dab2ip
(Rattus norvegicus)
DAB2IP
(Bos taurus)
CG42684
(Drosophila melanogaster)
B0BMG0_XENTR
(Xenopus laevis)
DAB2IP
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
Ras GTPase activator activity, plasma membrane, negative regulation of cell growth, negative regulation of epidermal growth factor receptor signaling pathway, protein binding, cytoplasm, intracellular, protein N-terminus binding, negative regulation of Ras protein signal transduction, positive regulation of apoptosis, positive regulation of JUN kinase activity, protein phosphatase 2A binding, GTPase activator activity, positive regulation of transcription from RNA polymerase II promoter, activation of JUN kinase activity, protein kinase binding, regulation of small GTPase mediated signal transduction, protein homodimerization activity, negative regulation of MAP kinase activity, negative regulation of transcription from RNA polymerase II promoter, negative regulation of epithelial cell proliferation, negative regulation of fibroblast proliferation, negative regulation of NF-kappaB transcription factor activity, positive regulation of Ras GTPase activity, negative regulation of epithelial to mesenchymal transition, negative regulation of epithelial cell migration, negative regulation of I-kappaB kinase/NF-kappaB cascade, death receptor binding, negative regulation of Ras GTPase activity, apoptosis in response to endoplasmic reticulum stress, cellular response to tumor necrosis factor, positive regulation of signal transduction, negative regulation of canonical Wnt receptor signaling pathway, mitogen-activated protein kinase kinase kinase binding, intrinsic to internal side of plasma membrane, signaling adaptor activity, negative regulation of protein serine/threonine kinase activity, 14-3-3 protein binding, positive regulation of protein serine/threonine kinase activity, cellular response to epidermal growth factor stimulus, negative regulation of catenin import into nucleus |
| InterPro ID |
IPR000008, IPR001936, IPR001849, IPR021887 |
| Gene Ontology ID |
GO:0007257, GO:0051056, GO:0042803, GO:0005622, GO:0005515, GO:0047485, GO:0005737, GO:0005886, GO:0050680, GO:0005096, GO:0005099, GO:0043065, GO:0019901, GO:0000122, GO:0051721, GO:0042059, GO:0045944, GO:0043507, GO:0046580, GO:0043407, GO:0030308, GO:0010719, GO:0009967, GO:0010633, GO:0034261, GO:0048147, GO:0005123, GO:0090090, GO:0043124, GO:0031435, GO:0035414, GO:0071356, GO:0032088, GO:0070059, GO:0032320, GO:0031235, GO:0071364, GO:0035591, GO:0071902, GO:0071901, GO:0071889 |
| InterPro Term |
C2_Ca-dep, Pleckstrin_homology, RasGAP, DUF3498 |
| Ensembl Family |
ENSFM00250000000610 |
| Ensembl Family Description |
RAS GTPASE ACTIVATING |
| Entrez Gene ID |
153090 |
| HGNC Symbol |
DAB2IP |
| EMBL-Bank ID |
AB051530, AF367051, AL357936, CH471090, AY032952, AL365274, BC146762, AK124610 |
| Ensembl Protein ID |
ENSP00000409327, ENSP00000362887, ENSP00000377872, ENSP00000259371, ENSP00000310827, ENSP00000386183 |
| RefSeq ID |
NP_115941, NM_138709, NP_619723, NM_032552 |
| Description |
DAB2 interacting protein [Source:HGNC Symbol;Acc:17294] |
| UniProt Accession |
B5MDY7, B3KW96, B0QZB2, B0QZ97, Q5VWQ7, Q5VWQ8, F6R503, F8WA47 |
| UniGene ID |
Hs.707109, Hs.522378 |
| Ensembl Gene ID |
ENSG00000136848 |
| Ensembl Transcript ID |
ENST00000373782, ENST00000436835, ENST00000487716, ENST00000408936, ENST00000259371, ENST00000465078, ENST00000459906, ENST00000489314, ENST00000394340, ENST00000309989 |
| Design Element |
ENST00000487716, ENST00000465078, 72473_at, gnf1h02220_s_at, ENST00000489314, 45741_at, 228942_s_at, Hs.238465.1.S1_3p_at, 45742_g_at, gnf1h08376_at, ENST00000408936, ENST00000459906, ENST00000436835, gnf1h02219_at, ENST00000259371, Hs.238465.0.S1_3p_at, ENST00000373782, Hs.238465.0.S1_3p_x_at, ENST00000394340, 51735_s_at, 91760_at, 225020_at, Hs.238465.1.S1_3p_x_at, ENST00000309989 |
| Search EB-eye |
ENSG00000136848
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