KLF4
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Homo sapiens |
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KLF4 is differentially expressed in 353 experiments: 155 organism parts: liver, lung, ... (153 more);, 226 disease states: normal, colon carcinoma, ... (224 more);, 129 cell types 454 cell lines 62 compound treatments and 80 other conditions. |
| Synonyms |
GKLF, EZF |
| Orthologs |
A7YWE2_BOVIN
(Bos taurus)
KLF4
(Danio rerio)
Q4H2J1_CIOIN
(Ciona intestinalis)
Klf4
(Mus musculus)
Klf4
(Rattus norvegicus)
klf4
(Xenopus laevis)
KLF4
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
epidermal cell differentiation, stem cell maintenance, double-stranded DNA binding, regulation of cell proliferation, intracellular, negative regulation of cell proliferation, transcription, DNA-dependent, response to chemical stimulus, epidermis morphogenesis, transcription from RNA polymerase II promoter, transcription factor binding, cell differentiation, sequence-specific DNA binding, positive regulation of transcription from RNA polymerase II promoter, nucleus, regulation of cell differentiation, transcription factor complex, negative regulation of protein kinase B signaling cascade, chromatin, regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, zinc ion binding, post-embryonic camera-type eye development, negative regulation of ERK1 and ERK2 cascade, negative regulation of smooth muscle cell proliferation, fat cell differentiation, negative regulation of muscle hyperplasia, response to retinoic acid, sequence-specific DNA binding transcription factor activity, phosphatidylinositol 3-kinase regulator activity, RNA polymerase II transcription factor binding, sequence-specific DNA binding transcription factor recruiting transcription factor activity, transcription regulatory region DNA binding, negative regulation of phosphatidylinositol 3-kinase cascade |
| Gene Ontology ID |
GO:0008134, GO:0003690, GO:0008285, GO:0008270, GO:0009913, GO:0003700, GO:0042221, GO:0048730, GO:0005622, GO:0005634, GO:0005667, GO:0000785, GO:0019827, GO:0042127, GO:0006357, GO:0006351, GO:0006366, GO:0051898, GO:0045595, GO:0045944, GO:0043565, GO:0045893, GO:0030154, GO:0035014, GO:0048662, GO:0014067, GO:0032526, GO:0031077, GO:0014740, GO:0044212, GO:0045444, GO:0070373, GO:0001085, GO:0001010 |
| InterPro Term |
Znf_C2H2-like, Znf_C2H2 |
| InterPro ID |
IPR007087, IPR015880 |
| Ensembl Family |
ENSFM00500000270362 |
| Ensembl Family Description |
KRUEPPEL FACTOR 4 EPITHELIAL ZINC FINGER EZF GUT ENRICHED KRUEPPEL FACTOR |
| HGNC Symbol |
KLF4 |
| UniProt Accession |
B7ZBT2, B7ZBT1, Q5T3J6 |
| Entrez Gene ID |
9314 |
| Ensembl Protein ID |
ENSP00000396294, ENSP00000404922, ENSP00000363804, ENSP00000399921 |
| Ensembl Gene ID |
ENSG00000136826 |
| RefSeq ID |
NM_004235, NP_004226 |
| EMBL-Bank ID |
AL360218, AL359552 |
| UniGene ID |
Hs.376206 |
| Description |
Kruppel-like factor 4 (gut) [Source:HGNC Symbol;Acc:6348] |
| Ensembl Transcript ID |
ENST00000493306, ENST00000497048, ENST00000411706, ENST00000374672, ENST00000420475, ENST00000439281 |
| Design Element |
ENST00000374672, U70663_at, ENST00000493306, 36214_at, 221841_s_at, g4758321_3p_a_at, ENST00000411706, 48587_at, ENST00000439281, ENST00000420475, ENST00000497048, 220266_s_at |
| Search EB-eye |
ENSG00000136826
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