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DSC1
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Homo sapiens
DSC1 is differentially expressed in 147 experiments: 92 organism parts: skin, lung, ... (90 more);, 96 disease states: normal, "AIDS-KS, HIV+, nodular (late) stage", ... (94 more);, 49 cell types 74 cell lines 15 compound treatments and 55 other conditions.
Synonyms CDHF1
Orthologs dsc2l (Danio rerio)   Dsc1 (Mus musculus)   F1NJD7_CHICK (Gallus gallus)   A6QR67_BOVIN (Bos taurus)   D3ZJR8_RAT (Rattus norvegicus)   dsc3 (Xenopus laevis)   DSC1 (Canis familiaris)   (Compare orthologs)
Gene Ontology Term plasma membrane, protein binding, membrane, homophilic cell adhesion, membrane fraction, cell junction, cell adhesion, gap junction, integral to membrane, calcium ion binding, desmosome
InterPro Term Cadherin, Cadherin_cytoplasmic-dom, Desmo_cadherin, Cadherin_pro, Desmocollin
UniProt Accession Q9HB00, Q08554
Search EB-eye ENSG00000134765
Show more properties
Experimental Factors
Organism part

studied in E-GEOD-803, E-GEOD-15765, E-AFMX-5, E-MEXP-1251, E-GEOD-1577, ... (24 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell line

studied in E-GEOD-14464, E-GEOD-19639, E-GEOD-2450, E-GEOD-24147, E-GEOD-19480, ... (18 experiments)

Factor Value U/D Experiments
MCF-10A
2
 E-TABM-420, E-GEOD-14990
MCF-7
2
 E-GEOD-19639, E-GEOD-20081
MDA435
1
 E-GEOD-20089
NCIH322
1
 E-MTAB-37
NCIH1092
1
 E-MTAB-37
MKN7
1
 E-GEOD-15460
68 more value(s).


Cell type

studied in E-GEOD-18811, E-AFMX-5, E-TABM-40, E-MEXP-1251, E-MTAB-25, ... (24 experiments)

Factor Value U/D Experiments
plasma cell
1
 E-MEXP-2360
leydig cell
1
 E-MTAB-25
immortalized cell culture
1
 E-GEOD-14990
iPSC derived from hASC using minicircle reprogramming vector
1
 E-GEOD-20033
ADC
1
 E-GEOD-19188
CD8+CD28+
1
 E-MEXP-2345
43 more value(s).


Disease state

studied in E-GEOD-3307, E-MEXP-1922, E-GEOD-19743, E-GEOD-1577, E-MEXP-2442, ... (23 experiments)

Factor Value U/D Experiments
colorectal adenocarcinoma
2
 E-MTAB-62, E-MTAB-37
AIDS-KS, HIV+, nodular (late) stage
2
 E-MTAB-62, E-MEXP-66
lung adenocarcinoma
2
 E-MTAB-37, E-MTAB-62
chronic myelogenous leukemia, indolent
1
 E-MTAB-62
Breast adenocarcinoma
1
 E-MTAB-62
leiomyosarcoma
1
 E-MEXP-1922
90 more value(s).


Compound treatment

studied in E-MEXP-1601, E-GEOD-5258, E-GEOD-5741, E-GEOD-6932, E-GEOD-412, ... (12 experiments)

Factor Value U/D Experiments
none
1
5
 E-GEOD-5741, E-GEOD-412, E-GEOD-5824, E-MEXP-1601, E-GEOD-7307, ... (6 experiments)
2-(3,4,5-trimethoxy-phenylamino)-pyrrolo[2,3-d]pyrimidines
1
 E-GEOD-6932
dimethyl sulfoxide
6
1
 E-GEOD-6932
LDL
1
 E-GEOD-5741
ox-LDL
1
 E-GEOD-5741
rapamycin
1
 E-GEOD-5824
9 more value(s).


Agent

studied in E-GEOD-19519

Factor Value U/D Experiments
thapsigargin
1
 E-GEOD-19519
tunicamycin
1
 E-GEOD-19519
DMSO
1
 E-GEOD-19519


Biosource provider
studied in E-GEOD-20559

BioSourceProvider
studied in E-GEOD-19519, E-GEOD-19480

Bmngrd
studied in E-GEOD-20194, E-GEOD-16716

Clinical history
studied in E-GEOD-19743, E-GEOD-7967, E-GEOD-2171, E-GEOD-21589, E-GEOD-16363, ... (6 experiments)

Clinical info
studied in E-GEOD-19743, E-MTAB-37, E-GEOD-6710, E-GEOD-19348, E-MEXP-1251, ... (7 experiments)

Clinical treatment
studied in E-GEOD-2171, E-GEOD-6532

coriell cell line repository identifier
studied in E-GEOD-19519

Developmental stage
studied in E-GEOD-1614, E-GEOD-20033, E-MTAB-62

dfs time (months)
studied in E-GEOD-21653

Disease staging
studied in E-GEOD-19743, E-GEOD-1561

Environmental stress
studied in E-GEOD-1643

Epiregulin elisa conc ng ml
studied in E-GEOD-5851

Er
studied in E-GEOD-20194, E-GEOD-16716

Estrogen receptor status
studied in E-GEOD-6532, E-GEOD-20194, E-GEOD-16716

Ethnic group
studied in E-GEOD-20194, E-GEOD-16716

Genetic modification
studied in E-GEOD-20847

Genotype
studied in E-GEOD-17476, E-GEOD-22593, E-TABM-601, E-GEOD-17347, E-GEOD-21293 ... (5 experiments)

Gestation age
studied in E-GEOD-14334

369 groups
studied in E-MTAB-62

4 groups from blood to incompletely diff
studied in E-MTAB-62

96 groups
studied in E-MTAB-62

Growth condition
studied in E-TABM-263, E-TABM-127

Her2 fish
studied in E-GEOD-20194, E-GEOD-16716

Her2 ihc
studied in E-GEOD-20194, E-GEOD-16716

Histology
studied in E-TABM-234, E-GEOD-21653, E-TABM-276, E-GEOD-20194, E-GEOD-16716 ... (5 experiments)

Individual
studied in E-TABM-325, E-TABM-740, E-MEXP-2069, E-GEOD-19330, E-TABM-666, ... (16 experiments)

Infection
studied in E-GEOD-2405, E-GEOD-12108, E-GEOD-980

Injury
studied in E-GEOD-19743

Ki67 ihc
studied in E-GEOD-21653

15 meta groups
studied in E-MTAB-62

4 meta groups
studied in E-MTAB-62

6 meta groups
studied in E-MTAB-62

Metastasis
studied in E-GEOD-18105

Nbefore
studied in E-GEOD-20194, E-GEOD-16716

Observation
studied in E-TABM-276

Organism
studied in E-TABM-84

Organism status
studied in E-GEOD-19188

Phenotype
studied in E-GEOD-26495, E-GEOD-1460

Population
studied in E-GEOD-4922, E-GEOD-4342

Progesterone receptor status
studied in E-GEOD-6532

Protocol type
studied in E-GEOD-3254, E-GEOD-21837

Qpcr egfr dct
studied in E-GEOD-5851

Qrt pcr areg dct
studied in E-GEOD-5851

Replicate
studied in E-GEOD-10797

RNAi
studied in E-GEOD-3697, E-MEXP-1857

Sampling time point
studied in E-GEOD-16797, E-GEOD-19743, E-GEOD-21374

Sex
studied in E-GEOD-7307

Stimulation
studied in E-GEOD-20114

Survival time
studied in E-GEOD-3494, E-GEOD-19188

Tbefore
studied in E-GEOD-20194, E-GEOD-16716

Transfection
studied in E-GEOD-14680

Treatment
studied in E-GEOD-16837, E-MEXP-973, E-GEOD-19246, E-GEOD-13818

Treatment code
studied in E-GEOD-20194, E-GEOD-16716

Treatments comments
studied in E-GEOD-20194, E-GEOD-16716

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Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM