NOTCH2
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Homo sapiens |
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NOTCH2 is differentially expressed in 332 experiments: 175 organism parts: bone marrow, prostate, ... (173 more);, 246 disease states: normal, glioblastoma, ... (244 more);, 119 cell types 536 cell lines 45 compound treatments and 82 other conditions. |
| Orthologs |
NOTCH2
(Gallus gallus)
Q2L697_CIOIN
(Ciona intestinalis)
Notch2
(Mus musculus)
Notch2
(Rattus norvegicus)
NOTCH2
(Bos taurus)
NOTCH2 (2 of 2)
(Danio rerio)
N
(Drosophila melanogaster)
NOTCH2
(Xenopus laevis)
notch2
(Danio rerio)
NOTCH2
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0009887, GO:0008285, GO:0009986, GO:0016049, GO:0016020, GO:0016021, GO:0007050, GO:0007275, GO:0007220, GO:0007219, GO:0007399, GO:0042246, GO:0005509, GO:0005515, GO:0005576, GO:0004872, GO:0006916, GO:0006917, GO:0005634, GO:0005654, GO:0005886, GO:0005887, GO:0005829, GO:0005788, GO:0050793, GO:0019827, GO:0006355, GO:0001709, GO:0046579, GO:0030154, GO:0030097, GO:0010467, GO:0003706, GO:0005796, GO:0046849 |
| InterPro Term |
Notch_dom, Notch_NOD_dom, Ankyrin_rpt, Ankyrin_rpt-contain_dom, EGF_extracell, EGF, EGF_3, Notch, Notch_NODP_dom, EGF-like, Notch_2, DUF3454_notch, EGF-like_Ca-bd |
| Gene Ontology Term |
cytosol, plasma membrane, protein binding, regulation of transcription, DNA-dependent, stem cell maintenance, negative regulation of cell proliferation, cell fate determination, membrane, cell cycle arrest, extracellular region, anti-apoptosis, cell differentiation, cell growth, tissue regeneration, Notch receptor processing, hemopoiesis, induction of apoptosis, multicellular organismal development, integral to plasma membrane, nucleus, receptor activity, nervous system development, Notch signaling pathway, regulation of developmental process, integral to membrane, nucleoplasm, cell surface, endoplasmic reticulum lumen, calcium ion binding, organ morphogenesis, positive regulation of Ras protein signal transduction, bone remodeling, Golgi lumen, gene expression, ligand-regulated transcription factor activity |
| InterPro ID |
IPR010660, IPR011656, IPR000742, IPR000800, IPR006209, IPR006210, IPR001881, IPR008297, IPR013111, IPR020683, IPR002110, IPR022336, IPR024600 |
| Ensembl Family |
ENSFM00500000269589 |
| EMBL-Bank ID |
AF308601, GQ231534, AL512503, AL133036, U50549, AL359752, AL596222, U77493, AF315356 |
| UniProt Accession |
D2WEZ3, Q13560, Q04721, Q9UFD5, F5H255, F8WA92 |
| RefSeq ID |
NP_077719, NM_024408, NM_001200001, NP_001186930 |
| UniGene ID |
Hs.601926, Hs.487360, Hs.619910 |
| Description |
notch 2 [Source:HGNC Symbol;Acc:7882] |
| Ensembl Protein ID |
ENSP00000256646, ENSP00000384752, ENSP00000358348, ENSP00000438937, ENSP00000439516 |
| Entrez Gene ID |
4853 |
| Ensembl Gene ID |
ENSG00000134250 |
| HGNC Symbol |
NOTCH2 |
| Ensembl Family Description |
NEUROGENIC LOCUS NOTCH HOMOLOG PRECURSOR NOTCH [CONTAINS NOTCH EXTRACELLULAR TRUNCATION; NOTCH INTRACELLULAR |
| Ensembl Transcript ID |
ENST00000401649, ENST00000493703, ENST00000369342, ENST00000478864, ENST00000539617, ENST00000479412, ENST00000256646, ENST00000489731, ENST00000538680 |
| Gene-Disease Assocation |
ALAGILLE SYNDROME 2; ALGS2, HAJDU-CHENEY SYNDROME; HJCYS |
| Design Element |
g11275977_3p_a_at, ENST00000478864, 212377_s_at, 202443_x_at, Hs.8121.2.A1_3p_a_at, ENST00000538680, ENST00000401649, Hs.8121.3.A1_3p_a_at, g13249343_3p_a_at, 65285_r_at, 210756_s_at, ENST00000369342, ENST00000539617, ENST00000256646, 202445_s_at, ENST00000493703, 38083_at, ENST00000489731, ENST00000479412, 48486_at, 227067_x_at |
| Search EB-eye |
ENSG00000134250
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