MEN1
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Homo sapiens |
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MEN1 is differentially expressed in 223 experiments: 78 organism parts: liver, blood, ... (76 more);, 147 disease states: normal, control, ... (145 more);, 67 cell types 255 cell lines 25 compound treatments and 55 other conditions. |
| Orthologs |
Men1
(Rattus norvegicus)
men1
(Danio rerio)
ENSCING00000001396
(Ciona intestinalis)
Men1
(Mus musculus)
MEN1_BOVIN
(Bos taurus)
MEN1 (2 of 2)
(Danio rerio)
Mnn1
(Drosophila melanogaster)
men1
(Xenopus laevis)
A2SXS5_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
response to UV, cytosol, positive regulation of cell division, embryo development, DNA binding, positive regulation of caspase activity, negative regulation of transcription, DNA-dependent, protein binding, cleavage furrow, DNA repair, cytoplasm, double-stranded DNA binding, negative regulation of cell proliferation, protein complex, histone methylation, protein N-terminus binding, MAPKKK cascade, cell cycle arrest, nuclear matrix, positive regulation of transforming growth factor beta receptor signaling pathway, positive regulation of apoptosis, negative regulation of organ growth, soluble fraction, hemopoiesis, positive regulation of transcription from RNA polymerase II promoter, Y-form DNA binding, nucleus, negative regulation of JNK cascade, chromatin remodeling, chromatin binding, four-way junction DNA binding, chromatin, protein binding, bridging, negative regulation of transcription from RNA polymerase II promoter, response to DNA damage stimulus, response to gamma radiation, brain development, negative regulation of cell cycle, positive regulation of transcription, DNA-dependent, negative regulation of cyclin-dependent protein kinase activity, histone methyltransferase complex, histone-lysine N-methyltransferase activity, osteoblast fate commitment, negative regulation of osteoblast differentiation, negative regulation of telomerase activity, positive regulation of histone methylation, embryonic skeletal system morphogenesis, ossification, osteoblast development, positive regulation of cell differentiation, leukocyte homeostasis, histone lysine methylation, maternal process involved in female pregnancy, regulation of activin receptor signaling pathway, positive regulation of osteoblast differentiation, palate development, R-SMAD binding, positive regulation of protein binding, negative regulation of protein phosphorylation, negative regulation of sequence-specific DNA binding transcription factor activity, transcription regulatory region DNA binding |
| Ensembl Family |
ENSFM00250000003371 |
| Gene Ontology ID |
GO:0003682, GO:0003677, GO:0003690, GO:0008285, GO:0010332, GO:0009411, GO:0007050, GO:0016571, GO:0016363, GO:0009790, GO:0007420, GO:0030674, GO:0030511, GO:0005625, GO:0005515, GO:0047485, GO:0005737, GO:0005634, GO:0005829, GO:0006974, GO:0046329, GO:0043065, GO:0000785, GO:0045736, GO:0000165, GO:0051781, GO:0000122, GO:0006338, GO:0045786, GO:0018024, GO:0043280, GO:0043234, GO:0006281, GO:0045944, GO:0046621, GO:0045892, GO:0045893, GO:0000403, GO:0000400, GO:0043433, GO:0030097, GO:0035097, GO:0032154, GO:0060021, GO:0060135, GO:0048704, GO:0002051, GO:0002076, GO:0051974, GO:0001933, GO:0031062, GO:0001776, GO:0032925, GO:0045669, GO:0045668, GO:0045597, GO:0001503, GO:0044212, GO:0034968, GO:0070412, GO:0032092 |
| InterPro ID |
IPR007747 |
| Ensembl Family Description |
MENIN |
| InterPro Term |
Menin |
| EMBL-Bank ID |
U93237, U93236, AP001462, EF443096, EF443095, EF443094, EF443093, EF443092, EF443091, AJ297485, AJ297487, AJ297486, AJ297489, AJ297488, BC002544, BC002664, GQ433363, EF443097 |
| Ensembl Protein ID |
ENSP00000388016, ENSP00000377901, ENSP00000377899, ENSP00000411218, ENSP00000396940, ENSP00000337088, ENSP00000413944, ENSP00000394933, ENSP00000402752, ENSP00000366543, ENSP00000366533, ENSP00000366530, ENSP00000366538, ENSP00000323747, ENSP00000308975 |
| HGNC Symbol |
MEN1 |
| UniProt Accession |
C9DZM4, Q9GZQ5, O00255, E7EN32, E7ENS2, E7EPR4, E7ET29 |
| Entrez Gene ID |
4221 |
| Ensembl Gene ID |
ENSG00000133895 |
| RefSeq ID |
NP_570712, NP_570711, NP_570714, NP_570713, NP_570716, NP_570715, NM_130799, NM_130804, NM_130803, NM_130802, NM_130801, NM_130800, NP_000235, NM_000244 |
| UniGene ID |
Hs.423348 |
| Description |
multiple endocrine neoplasia I [Source:HGNC Symbol;Acc:7010] |
| Ensembl Transcript ID |
ENST00000312049, ENST00000377326, ENST00000377321, ENST00000377316, ENST00000377313, ENST00000424912, ENST00000478548, ENST00000429702, ENST00000315422, ENST00000440873, ENST00000443283, ENST00000337652, ENST00000487019, ENST00000413626, ENST00000394374, ENST00000394376, ENST00000450708 |
| Gene-Disease Assocation |
MULTIPLE ENDOCRINE NEOPLASIA, TYPE I; MEN1, HYPERPARATHYROIDISM 1; HRPT1 |
| Design Element |
ENST00000478548, U93237_rna2_at, ENST00000413626, ENST00000394376, ENST00000394374, ENST00000337652, ENST00000429702, 448_s_at, ENST00000377316, ENST00000443283, ENST00000377313, ENST00000377326, ENST00000377321, 202645_s_at, g4557744_3p_a_at, ENST00000424912, ENST00000440873, ENST00000450708, ENST00000312049, ENST00000487019, ENST00000315422 |
| Search EB-eye |
ENSG00000133895
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