KRAS
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Homo sapiens |
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KRAS is differentially expressed in 364 experiments: 161 organism parts: cerebellum, bone marrow, ... (159 more);, 255 disease states: normal, control, ... (253 more);, 109 cell types 505 cell lines 49 compound treatments and 89 other conditions. |
| Synonyms |
KRAS1, KRAS2 |
| Orthologs |
RAS2
(Saccharomyces cerevisiae)
Kras
(Mus musculus)
KRAS
(Gallus gallus)
RAS1
(Saccharomyces cerevisiae)
KRAS
(Bos taurus)
Kras
(Rattus norvegicus)
Ras85D
(Drosophila melanogaster)
O62857_CANFA
(Canis familiaris)
(Compare orthologs)
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| Ensembl Family Description |
RAS PRECURSOR |
| Gene Ontology Term |
plasma membrane, GDP binding, GTPase activity, protein binding, cytokine-mediated signaling pathway, visual learning, epidermal growth factor receptor signaling pathway, intracellular, positive regulation of cell proliferation, membrane, intracellular protein transport, social behavior, MAPKKK cascade, insulin receptor signaling pathway, positive regulation of MAP kinase activity, blood coagulation, membrane raft, membrane fraction, GTP catabolic process, GTP binding, activation of MAPKK activity, actin cytoskeleton organization, Ras protein signal transduction, axon guidance, small GTPase mediated signal transduction, nucleotide binding, positive regulation of NF-kappaB transcription factor activity, nucleocytoplasmic transport, signal transduction, protein transport, mitochondrion, negative regulation of neuron apoptosis, positive regulation of nitric-oxide synthase activity, striated muscle cell differentiation, response to mineralocorticoid stimulus, regulation of long-term neuronal synaptic plasticity, leukocyte migration, LRR domain binding, positive regulation of Rac protein signal transduction, regulation of synaptic transmission, GABAergic, nerve growth factor receptor signaling pathway, Ral guanyl-nucleotide exchange factor activity, GMP binding, response to glucocorticoid stimulus |
| Gene Ontology ID |
GO:0008286, GO:0008284, GO:0016020, GO:0015031, GO:0003924, GO:0007173, GO:0007165, GO:0007264, GO:0007265, GO:0008542, GO:0007411, GO:0007596, GO:0051092, GO:0005622, GO:0005624, GO:0005525, GO:0005515, GO:0006913, GO:0005739, GO:0006886, GO:0005886, GO:0000165, GO:0000166, GO:0000186, GO:0019221, GO:0043524, GO:0006184, GO:0043406, GO:0030036, GO:0045121, GO:0019003, GO:0035176, GO:0048011, GO:0008321, GO:0051385, GO:0051384, GO:0051146, GO:0051000, GO:0048169, GO:0030275, GO:0019002, GO:0050900, GO:0035022, GO:0032228 |
| InterPro ID |
IPR000795, IPR006689, IPR005225, IPR001806, IPR002041, IPR013684, IPR003578, IPR003579, IPR020849 |
| InterPro Term |
Ran_GTPase, MIRO-like, ProtSyn_GTP-bd, Small_GTPase, Small_GTP-bd_dom, Small_GTPase_ARF/SAR, Small_GTPase_Ras, Small_GTPase_Rho, Small_GTPase_Rab_type |
| Ensembl Family |
ENSFM00500000269718 |
| EMBL-Bank ID |
BT007153, AF285779, M30539, X01669, M19990, L00048, L00049, L00045, L00047, L00046, S68580, AF493917, CH471094, EU332849, M54968, K03209, K03210, AK292510, K01519, K01520, X02825, BC013572, M34904, M25876, EF685661, EF685662, HM459605 |
| RefSeq ID |
NM_033360, NP_203524, NP_004976, NM_004985 |
| UniProt Accession |
Q9UM97, Q71SP6, P01116, P78460, E5FF39 |
| UniGene ID |
Hs.691064, Hs.594741, Hs.690627, Hs.675166 |
| Gene-Disease Assocation |
BLADDER CANCER, CARDIOFACIOCUTANEOUS SYNDROME, PANCREATIC CANCER, LUNG CANCER, GASTRIC CANCER, BREAST CANCER, COSTELLO SYNDROME, GASTRIC CANCER, HEREDITARY DIFFUSE; HDGC, LEUKEMIA, ACUTE MYELOID; AML, JUVENILE MYELOMONOCYTIC LEUKEMIA; JMML, NOONAN SYNDROME 3; NS3 |
| Ensembl Gene ID |
ENSG00000133703 |
| Entrez Gene ID |
3845 |
| Description |
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog [Source:HGNC Symbol;Acc:6407] |
| Ensembl Protein ID |
ENSP00000308495, ENSP00000256078, ENSP00000452512, ENSP00000451856 |
| HGNC Symbol |
KRAS |
| Ensembl Transcript ID |
ENST00000556131, ENST00000311936, ENST00000256078, ENST00000557334 |
| Design Element |
204010_s_at, M54968_at, Hs.184050.0.S1_3p_a_at, g4826811_3p_a_at, 32159_at, 1940_at, 204009_s_at, Hs2.422851.1.A1_3p_x_at, Hs.184050.1.A1_3p_a_at, Hs2.422851.1.A1_3p_at, 231640_at, 214352_s_at, 1559203_s_at, ENST00000311936, Hs.184050.4.A1_3p_at, ENST00000556131, 1559204_x_at, ENST00000256078, ENST00000557334, 1559203_3p_s_at |
| Search EB-eye |
ENSG00000133703
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