ALOX5AP
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Homo sapiens |
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ALOX5AP is differentially expressed in 250 experiments: 108 organism parts: lung, bone marrow, ... (106 more);, 218 disease states: normal, glioblastoma, ... (216 more);, 106 cell types 385 cell lines 27 compound treatments and 68 other conditions. |
| Synonyms |
FLAP |
| Orthologs |
alox5ap
(Danio rerio)
Alox5ap
(Mus musculus)
ALOX5AP
(Gallus gallus)
AL5AP_BOVIN
(Bos taurus)
Alox5ap
(Rattus norvegicus)
alox5ap
(Xenopus laevis)
ALOX5AP
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0016020, GO:0016021, GO:0008047, GO:0031965, GO:0042803, GO:0005515, GO:0047485, GO:0005635, GO:0005634, GO:0005789, GO:0005783, GO:0005792, GO:0019899, GO:0019370, GO:0046982, GO:0004051, GO:0002540, GO:0050544, GO:0070207, GO:0071277 |
| Gene Ontology Term |
leukotriene biosynthetic process, endoplasmic reticulum, protein binding, membrane, protein N-terminus binding, microsome, nucleus, protein heterodimerization activity, enzyme activator activity, nuclear envelope, protein homodimerization activity, integral to membrane, endoplasmic reticulum membrane, enzyme binding, nuclear membrane, arachidonate 5-lipoxygenase activity, cellular response to calcium ion, arachidonic acid binding, leukotriene production involved in inflammatory response, protein homotrimerization |
| InterPro ID |
IPR001129, IPR001446 |
| InterPro Term |
Membr-assoc_MAPEG, 5_LipOase_AP |
| Ensembl Family Description |
ARACHIDONATE 5 LIPOXYGENASE ACTIVATING FLAP MK 886 BINDING |
| Ensembl Family |
ENSFM00500000272786 |
| EMBL-Bank ID |
M60470, AL512642, X52195, AY619687, M63259, M63260, M63262, BC018538 |
| Gene-Disease Assocation |
STROKE, ISCHEMIC |
| Description |
arachidonate 5-lipoxygenase-activating protein [Source:HGNC Symbol;Acc:436] |
| Ensembl Gene ID |
ENSG00000132965 |
| RefSeq ID |
NM_001629, NP_001620, NP_001191335, NM_001204406 |
| Ensembl Protein ID |
ENSP00000369858 |
| HGNC Symbol |
ALOX5AP |
| UniProt Accession |
P20292 |
| Entrez Gene ID |
241 |
| Ensembl Transcript ID |
ENST00000380490, ENST00000479597 |
| Design Element |
37099_at, 60061_at, 204174_at, ENST00000479597, g4502058_3p_at, ENST00000380490, M63262_at |
| Search EB-eye |
ENSG00000132965
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