CASP9
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Homo sapiens |
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CASP9 is differentially expressed in 286 experiments: 137 organism parts: kidney, lung, ... (135 more);, 197 disease states: normal, breast carcinoma, ... (195 more);, 107 cell types 331 cell lines 40 compound treatments and 80 other conditions. |
| Synonyms |
ICE-LAP6, APAF-3, MCH6 |
| Orthologs |
F6YWD6_CIOIN
(Ciona intestinalis)
casp9
(Danio rerio)
Dcp-1
(Drosophila melanogaster)
Casp9
(Mus musculus)
F1NL59_CHICK
(Gallus gallus)
decay
(Drosophila melanogaster)
Ice
(Drosophila melanogaster)
CASP9
(Bos taurus)
Casp9
(Rattus norvegicus)
casp9
(Xenopus laevis)
Q45T68_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
response to UV, cytosol, protein binding, apoptosis, intracellular, peptidase activity, activation of caspase activity, activation of caspase activity by cytochrome c, fibroblast growth factor receptor signaling pathway, soluble fraction, cysteine-type endopeptidase activity, nucleus, enzyme activator activity, proteolysis, response to DNA damage stimulus, cysteine-type peptidase activity, regulation of apoptosis, apoptosome, induction of apoptosis by intracellular signals, cellular response to dexamethasone stimulus, nerve growth factor receptor signaling pathway, positive regulation of neuron apoptosis, phosphatidylinositol-mediated signaling |
| Gene Ontology ID |
GO:0008234, GO:0008233, GO:0048015, GO:0008047, GO:0009411, GO:0008635, GO:0008543, GO:0004197, GO:0005622, GO:0005625, GO:0005515, GO:0006915, GO:0006919, GO:0005634, GO:0005829, GO:0006974, GO:0042981, GO:0006508, GO:0048011, GO:0008629, GO:0043293, GO:0043525, GO:0071549 |
| InterPro Term |
Pept_C14_p10, Pept_C14_ICE_p20, Pept_C14_p45_core, Pept_C14_cat, Caspase_IL-1_beta, CARD |
| InterPro ID |
IPR001309, IPR011600, IPR017350, IPR015917, IPR002138, IPR001315 |
| Ensembl Family |
ENSFM00360000109926 |
| Ensembl Family Description |
CASPASE 9 PRECURSOR CASP 9 EC_3.4.22.62 APOPTOTIC PROTEASE MCH 6 APOPTOTIC PROTEASE ACTIVATING FACTOR 3 APAF 3 ICE APOPTOTIC PROTEASE 6 ICE LAP6 [CONTAINS CASPASE 9 SUBUNIT P35; CASPASE 9 SUBUNIT P10] |
| Ensembl Gene ID |
ENSG00000132906 |
| EMBL-Bank ID |
AB209147, AL512883, AB015653, AK303743, BC002452, AF093130, U60521, BC006463, AB019205, U56390, CH471167, BT006911, AF110376, AY214168, AB020979 |
| Ensembl Protein ID |
ENSP00000365034, ENSP00000365051, ENSP00000383588, ENSP00000408691, ENSP00000411304, ENSP00000396540, ENSP00000255256, ENSP00000330237, ENSP00000449216, ENSP00000449584 |
| UniGene ID |
Hs.329502 |
| RefSeq ID |
NP_127463, NP_001220, NM_001229, NM_032996 |
| UniProt Accession |
P55211, B4E1A3, Q59GG2, Q5JRU8, Q5JRU2, Q5JRU3, E9PCV5, F8VWA5, F8VVS7 |
| Entrez Gene ID |
842 |
| Description |
caspase 9, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:1511] |
| HGNC Symbol |
CASP9 |
| Ensembl Transcript ID |
ENST00000375890, ENST00000375874, ENST00000469637, ENST00000424908, ENST00000447522, ENST00000440484, ENST00000348549, ENST00000333868, ENST00000474305, ENST00000546424, ENST00000400777, ENST00000546969 |
| Design Element |
ENST00000440484, 203984_s_at, ENST00000424908, ENST00000469637, U60521_at, ENST00000400777, ENST00000333868, ENST00000447522, ENST00000546424, 487_g_at, ENST00000474305, ENST00000375890, ENST00000375874, ENST00000348549, 237451_x_at, 210775_x_at, Hs.34174.1.A1_3p_at, g5103139_3p_s_at, ENST00000546969, g1532150_3p_s_at, 486_at, 240437_at |
| Search EB-eye |
ENSG00000132906
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