TRAF3
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Homo sapiens |
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TRAF3 is differentially expressed in 310 experiments: 127 organism parts: lung, bone marrow, ... (125 more);, 197 disease states: normal, breast carcinoma, ... (195 more);, 91 cell types 407 cell lines 44 compound treatments and 71 other conditions. |
| Synonyms |
LAP1, CAP-1, CRAF1, CD40bp |
| Orthologs |
Traf3
(Rattus norvegicus)
TRAF3
(Gallus gallus)
traf3
(Danio rerio)
ENSCING00000001576
(Ciona intestinalis)
ENSCING00000000789
(Ciona intestinalis)
ENSCING00000002932
(Ciona intestinalis)
Traf3
(Mus musculus)
TRAF3
(Bos taurus)
ENSCING00000014078
(Ciona intestinalis)
ENSCING00000000553
(Ciona intestinalis)
ENSCING00000000554
(Ciona intestinalis)
ENSCING00000017424
(Ciona intestinalis)
ENSCING00000015912
(Ciona intestinalis)
Traf-like
(Drosophila melanogaster)
traf3
(Xenopus laevis)
TRAF3
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, ligase activity, protein binding, cytoplasm, innate immune response, metal ion binding, signal transducer activity, induction of apoptosis, protein kinase binding, ubiquitin-protein ligase activity, endosome, regulation of proteolysis, signal transduction, mitochondrion, zinc ion binding, regulation of apoptosis, tumor necrosis factor-mediated signaling pathway, internal side of plasma membrane, toll-like receptor signaling pathway, negative regulation of NF-kappaB transcription factor activity, regulation of cytokine production, regulation of defense response to virus, regulation of interferon-beta production, CD40 receptor complex, negative regulation of type I interferon production |
| Gene Ontology ID |
GO:0008270, GO:0007165, GO:0016874, GO:0005515, GO:0004842, GO:0004871, GO:0006917, GO:0005737, GO:0005739, GO:0005829, GO:0005768, GO:0042981, GO:0019901, GO:0046872, GO:0030162, GO:0045087, GO:0009898, GO:0002224, GO:0001817, GO:0033209, GO:0032088, GO:0050688, GO:0032648, GO:0035631, GO:0032480 |
| InterPro ID |
IPR001293, IPR001841, IPR002083, IPR012227 |
| InterPro Term |
MATH, Znf_RING, Znf_TRAF, TNF_rcpt--assoc_TRAF |
| Ensembl Family Description |
TNF RECEPTOR ASSOCIATED FACTOR |
| Ensembl Family |
ENSFM00500000269755 |
| Ensembl Protein ID |
ENSP00000328003, ENSP00000332468, ENSP00000376500, ENSP00000445998, ENSP00000454207, ENSP00000453623, ENSP00000453032, ENSP00000453031 |
| RefSeq ID |
NM_145726, NM_145725, NM_003300, NP_003291, NP_663777, NP_663778, NM_001199427, NP_001186356 |
| UniProt Accession |
Q13114, A6NHG8 |
| Entrez Gene ID |
7187 |
| EMBL-Bank ID |
L38509, U21092, AL117209, U19260, U15637, BC075086, BC075087, AF110908, AL132801, BX247977, AK303172 |
| HGNC Symbol |
TRAF3 |
| Ensembl Gene ID |
ENSG00000131323 |
| Description |
TNF receptor-associated factor 3 [Source:HGNC Symbol;Acc:12033] |
| Ensembl Transcript ID |
ENST00000347662, ENST00000539721, ENST00000351691, ENST00000392745, ENST00000559734, ENST00000560371, ENST00000560463, ENST00000558700, ENST00000558880 |
| UniGene ID |
Hs.510528, Hs.599754 |
| Design Element |
ENST00000558700, 37057_s_at, ENST00000559734, ENST00000560371, 208315_x_at, U15637_s_at, g4507678_3p_at, ENST00000351691, g4507678_3p_a_at, g4507678_3p_x_at, ENST00000347662, 208315_3p_x_at, ENST00000560463, 221571_at, ENST00000392745, ENST00000558880, 43952_at, ENST00000539721, Hs.297660.1.S2_3p_at |
| Search EB-eye |
ENSG00000131323
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