CDKN1C
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Homo sapiens |
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CDKN1C is differentially expressed in 375 experiments: 136 organism parts: liver, placenta, ... (134 more);, 229 disease states: normal, control, ... (227 more);, 126 cell types 409 cell lines 59 compound treatments and 81 other conditions. |
| Synonyms |
BWCR, P57, BWS, KIP2 |
| Orthologs |
Cdkn1c
(Mus musculus)
Q2HJM8_BOVIN
(Bos taurus)
E9PTV7_RAT
(Rattus norvegicus)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008285, GO:0007049, GO:0007050, GO:0030511, GO:0000080, GO:0000079, GO:0004861, GO:0005515, GO:0005737, GO:0005634, GO:0050680, GO:0000122, GO:0045892, GO:0045893, GO:0042326, GO:0042551, GO:0004860, GO:0033673 |
| Gene Ontology Term |
negative regulation of transcription, DNA-dependent, protein binding, cytoplasm, negative regulation of cell proliferation, regulation of cyclin-dependent protein kinase activity, cell cycle arrest, G1 phase of mitotic cell cycle, positive regulation of transforming growth factor beta receptor signaling pathway, cell cycle, nucleus, negative regulation of transcription from RNA polymerase II promoter, cyclin-dependent protein kinase inhibitor activity, negative regulation of epithelial cell proliferation, positive regulation of transcription, DNA-dependent, neuron maturation, negative regulation of kinase activity, protein kinase inhibitor activity, negative regulation of phosphorylation |
| InterPro Term |
CDI |
| InterPro ID |
IPR003175 |
| Ensembl Family Description |
CYCLIN DEPENDENT KINASE INHIBITOR 1C CYCLIN DEPENDENT KINASE INHIBITOR P57 P57KIP2 |
| Ensembl Family |
ENSFM00600000922343 |
| UniGene ID |
Hs.604233, Hs.106070, Hs.727251 |
| EMBL-Bank ID |
D64137, AC013791, U48869, BC067842, U22398 |
| RefSeq ID |
NP_001116102, NP_001116103, NM_001122631, NM_001122630, NP_000067, NM_000076 |
| Ensembl Protein ID |
ENSP00000370101, ENSP00000411257, ENSP00000411552, ENSP00000413720, ENSP00000321019 |
| Entrez Gene ID |
1028 |
| Description |
cyclin-dependent kinase inhibitor 1C (p57, Kip2) [Source:HGNC Symbol;Acc:1786] |
| UniProt Accession |
P49918, A6NK88 |
| HGNC Symbol |
CDKN1C |
| Ensembl Gene ID |
ENSG00000129757 |
| Ensembl Transcript ID |
ENST00000471157, ENST00000414822, ENST00000380725, ENST00000313407, ENST00000430149, ENST00000440480 |
| Gene-Disease Assocation |
BECKWITH-WIEDEMANN SYNDROME; BWS |
| Design Element |
213182_x_at, Hs.106070.1.S1_3p_at, ENST00000430149, ENST00000313407, 219534_x_at, ENST00000440480, ENST00000380725, ENST00000414822, U22398_at, 38673_s_at, Hs.106070.3.S1_3p_a_at, 216894_x_at, ENST00000471157, 213348_at, 1787_at, 39545_at |
| Search EB-eye |
ENSG00000129757
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