NKX2-2
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Homo sapiens |
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NKX2-2 is differentially expressed in 140 experiments: 144 organism parts: amygdala, hypothalamus, ... (142 more);, 84 disease states: normal, Burkitt's lymphoma, ... (82 more);, 27 cell types 190 cell lines 17 compound treatments and 58 other conditions. |
| Synonyms |
NKX2B, NKX2.2 |
| Orthologs |
Nkx2-2
(Mus musculus)
nkx2.2a
(Danio rerio)
Nkx2-2
(Rattus norvegicus)
E1BBE1_BOVIN
(Bos taurus)
nkx2-2
(Xenopus laevis)
NKX2-2
(Canis familiaris)
vnd
(Drosophila melanogaster)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003682, GO:0003713, GO:0003700, GO:0007275, GO:0007224, GO:0007399, GO:0007420, GO:0048565, GO:0005515, GO:0005634, GO:0005654, GO:0006355, GO:0006351, GO:0045595, GO:0045944, GO:0043565, GO:0030154, GO:0060580, GO:0048708, GO:0048714, GO:0048665, GO:0051091, GO:0048468, GO:0014003, GO:0003326, GO:0003323, GO:0003329, GO:0003327, GO:0031018, GO:0044424, GO:0045665, GO:0045666, GO:0045597, GO:0021522, GO:0021529, GO:0021530, GO:0001159 |
| InterPro ID |
IPR001356, IPR020479 |
| Gene Ontology Term |
protein binding, regulation of transcription, DNA-dependent, transcription, DNA-dependent, smoothened signaling pathway, transcription factor binding, cell differentiation, sequence-specific DNA binding, positive regulation of transcription from RNA polymerase II promoter, multicellular organismal development, transcription coactivator activity, nucleus, regulation of cell differentiation, nervous system development, chromatin binding, nucleoplasm, brain development, digestive tract development, intracellular part, positive regulation of neuron differentiation, spinal cord oligodendrocyte cell fate specification, pancreatic PP cell fate commitment, astrocyte differentiation, spinal cord motor neuron differentiation, ventral spinal cord interneuron fate determination, positive regulation of oligodendrocyte differentiation, negative regulation of neuron differentiation, positive regulation of cell differentiation, spinal cord oligodendrocyte cell differentiation, endocrine pancreas development, oligodendrocyte development, pancreatic A cell fate commitment, neuron fate specification, cell development, sequence-specific DNA binding transcription factor activity, core promoter proximal region DNA binding, type B pancreatic cell development, type B pancreatic cell fate commitment, positive regulation of sequence-specific DNA binding transcription factor activity |
| InterPro Term |
Homeobox, Homeobox_eu |
| Ensembl Family Description |
HOMEOBOX NKX 2 HOMEOBOX NK 2 HOMOLOG B |
| Ensembl Family |
ENSFM00500000271549 |
| Entrez Gene ID |
4821 |
| UniGene ID |
Hs.516922 |
| EMBL-Bank ID |
AL133325, AF019414, AF019415, BC075093, BC075092 |
| Ensembl Protein ID |
ENSP00000366347 |
| HGNC Symbol |
NKX2-2 |
| Description |
NK2 homeobox 2 [Source:HGNC Symbol;Acc:7835] |
| UniProt Accession |
O95096 |
| Ensembl Gene ID |
ENSG00000125820 |
| RefSeq ID |
NP_002500, NM_002509 |
| Ensembl Transcript ID |
ENST00000377142 |
| Design Element |
206915_at, g4505400_3p_at, 33605_at, ENST00000377142, 33606_g_at |
| Search EB-eye |
ENSG00000125820
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