IL1B
close
Please copy/paste those URLs into your code to get same results in machine-readable formats:
|
Homo sapiens |
|
IL1B is differentially expressed in 293 experiments: 104 organism parts: lung, blood, ... (102 more);, 140 disease states: normal, acute myeloid leukemia, ... (138 more);, 111 cell types 335 cell lines 45 compound treatments and 76 other conditions. |
| Synonyms |
IL-1B, IL1F2, IL1-BETA |
| Orthologs |
Il1b
(Mus musculus)
O73909_CHICK
(Gallus gallus)
il1b
(Danio rerio)
Q5MAC0_BOVIN
(Bos taurus)
Il1b
(Rattus norvegicus)
il1b
(Xenopus laevis)
IL1B_CANFA
(Canis familiaris)
(Compare orthologs)
|
| InterPro ID |
IPR002348, IPR000975, IPR003297, IPR003296, IPR003294, IPR003502 |
| Gene Ontology Term |
cytosol, positive regulation of cell division, stored secretory granule, positive regulation of nitric oxide biosynthetic process, sequestering of triglyceride, elevation of cytosolic calcium ion concentration, apoptosis, vesicle, cytokine-mediated signaling pathway, ovulation, memory, negative regulation of cell proliferation, extracellular space, wound healing, positive regulation of gene expression, response to chemical stimulus, social behavior, learning or memory, growth factor activity, extracellular region, cell-cell signaling, protein domain specific binding, anti-apoptosis, response to hypoxia, cytokine activity, positive regulation of apoptosis, positive regulation of JUN kinase activity, positive regulation of JNK cascade, activation of MAPK activity, response to nutrient, positive regulation of transcription from RNA polymerase II promoter, positive regulation of histone acetylation, response to lipopolysaccharide, aging, immune response, response to drug, positive regulation of NF-kappaB transcription factor activity, regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of MAP kinase activity, response to gamma radiation, response to heat, signal transduction, negative regulation of insulin receptor signaling pathway, positive regulation of heterotypic cell-cell adhesion, positive regulation of calcidiol 1-monooxygenase activity, positive regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of adiponectin secretion, response to ozone, positive regulation of NF-kappaB import into nucleus, positive regulation of prostaglandin secretion, response to vitamin D, response to organic nitrogen, leukocyte migration, negative regulation of glutamate secretion, positive regulation of ERK1 and ERK2 cascade, cellular response to mechanical stimulus, positive regulation of stress-activated MAPK cascade, interleukin-1 receptor binding, negative regulation of lipid metabolic process, positive regulation of interleukin-2 biosynthetic process, positive regulation of T cell mediated immunity, positive regulation of chemokine biosynthetic process, response to morphine, negative regulation of lipid catabolic process, response to ATP, positive regulation of interleukin-8 production, chronic inflammatory response to antigenic stimulus, positive regulation of interferon-gamma production, positive regulation of vascular endothelial growth factor receptor signaling pathway, positive regulation of interleukin-6 production, positive regulation of histone phosphorylation, positive regulation of lipid catabolic process, response to estradiol stimulus, positive regulation of membrane protein ectodomain proteolysis, inflammatory response, positive regulation of T cell proliferation, regulation of insulin secretion, positive regulation of angiogenesis, positive regulation of interleukin-6 biosynthetic process, neutrophil chemotaxis, response to L-ascorbic acid, positive regulation vascular endothelial growth factor production, cellular response to organic substance, positive regulation of mitosis, embryo implantation, positive regulation of protein export from nucleus, response to glucocorticoid stimulus, negative regulation of glucose transport, positive regulation of protein phosphorylation, positive regulation of cell adhesion molecule production, smooth muscle adaptation, positive regulation of myosin light chain kinase activity, cellular response to drug, positive regulation of fever generation, response to organic cyclic compound, positive regulation of monocyte chemotactic protein-1 production, positive regulation of granulocyte macrophage colony-stimulating factor production, positive regulation of sequence-specific DNA binding transcription factor activity, interleukin-1 beta production |
| Gene Ontology ID |
GO:0010628, GO:0008285, GO:0008083, GO:0010332, GO:0009408, GO:0007165, GO:0007267, GO:0007204, GO:0042221, GO:0030728, GO:0030730, GO:0031982, GO:0007584, GO:0007568, GO:0042493, GO:0007611, GO:0007613, GO:0051092, GO:0005615, GO:0005576, GO:0006916, GO:0006915, GO:0006955, GO:0005829, GO:0005125, GO:0032496, GO:0046330, GO:0043065, GO:0019904, GO:0001934, GO:0043122, GO:0051781, GO:0000187, GO:0019221, GO:0042060, GO:0045944, GO:0043507, GO:0046627, GO:0001666, GO:0043407, GO:0030141, GO:0045429, GO:0035066, GO:0035176, GO:0010575, GO:0060559, GO:0034116, GO:0010243, GO:0010193, GO:0051384, GO:0042346, GO:0007566, GO:0002711, GO:0030593, GO:0051044, GO:0051091, GO:0002439, GO:0014050, GO:0014070, GO:0006954, GO:0030949, GO:0005149, GO:0050796, GO:0043123, GO:0032729, GO:0032757, GO:0032755, GO:0031622, GO:0046827, GO:0032874, GO:0045766, GO:0042102, GO:0043278, GO:0045833, GO:0045840, GO:0070164, GO:0071310, GO:0071260, GO:0070374, GO:0033591, GO:0045410, GO:0050900, GO:0033129, GO:0033198, GO:0050995, GO:0050996, GO:0033280, GO:0045080, GO:0045086, GO:0010829, GO:0032308, GO:0032355, GO:0014805, GO:0060355, GO:0032725, GO:0035505, GO:0035690, GO:0071639, GO:0032611 |
| InterPro Term |
IL1_HBGF, IL_rcpt_IL1RA, Interleukin_1, InterleukinIL1AB, InterleukinIL1B, IL1_propep |
| Ensembl Family Description |
INTERLEUKIN 1 BETA PRECURSOR IL 1 BETA |
| Ensembl Family |
ENSFM00250000002202 |
| EMBL-Bank ID |
BT007213, K02770, AY137079, X56087, M15330, X04500, M54933, CH471217, X02532, M15840, CR407679, BC008678, AC079753, BN000002, AB451494 |
| UniGene ID |
Hs.126256, Hs.700961 |
| Ensembl Protein ID |
ENSP00000409680, ENSP00000407219, ENSP00000400854, ENSP00000263341 |
| UniProt Accession |
B5BUQ8, P01584, C9JSC2, C9JVK0, C9JWV2 |
| Description |
interleukin 1, beta [Source:HGNC Symbol;Acc:5992] |
| Entrez Gene ID |
3553 |
| RefSeq ID |
NP_000567, NM_000576 |
| HGNC Symbol |
IL1B |
| Ensembl Gene ID |
ENSG00000125538 |
| Gene-Disease Assocation |
GASTRIC CANCER, HEREDITARY DIFFUSE; HDGC |
| Ensembl Transcript ID |
ENST00000491056, ENST00000487639, ENST00000416750, ENST00000432018, ENST00000418817, ENST00000263341, ENST00000477398, ENST00000496280 |
| Design Element |
ENST00000487639, 205067_at, g10835144_3p_at, ENST00000432018, g10835144_3p_s_at, 39402_at, ENST00000418817, ENST00000263341, 1520_s_at, ENST00000491056, ENST00000416750, ENST00000496280, ENST00000477398, X04500_at |
| Search EB-eye |
ENSG00000125538
|
 Show more
properties
|
|
