IRF1
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Homo sapiens |
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IRF1 is differentially expressed in 320 experiments: 135 organism parts: lung, spleen, ... (133 more);, 208 disease states: normal, control, ... (206 more);, 109 cell types 412 cell lines 64 compound treatments and 65 other conditions. |
| Synonyms |
MAR |
| Orthologs |
Q4H3B3_CIOIN
(Ciona intestinalis)
Irf1
(Mus musculus)
IRF1_CHICK
(Gallus gallus)
IRF1
(Bos taurus)
irf11
(Danio rerio)
Irf1
(Rattus norvegicus)
irf1
(Xenopus laevis)
IRF1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, DNA binding, protein binding, cytokine-mediated signaling pathway, transcription, DNA-dependent, blood coagulation, transcription from RNA polymerase II promoter, I-kappaB kinase/NF-kappaB cascade, sequence-specific DNA binding, positive regulation of transcription from RNA polymerase II promoter, nucleus, regulation of gene expression, nucleoplasm, response to heat, positive regulation of transcription, DNA-dependent, response to growth hormone stimulus, cellular response to retinoic acid, female pregnancy, cellular response to mechanical stimulus, cellular response to peptide hormone stimulus, positive regulation of cell death, cellular response to tumor necrosis factor, CD8-positive, alpha-beta T cell differentiation, positive regulation of interleukin-12 biosynthetic process, cellular response to interleukin-1, sequence-specific DNA binding transcription factor activity, interferon-gamma-mediated signaling pathway, type I interferon-mediated signaling pathway, negative regulation of tyrosine phosphorylation of Stat1 protein, cellular response to dsRNA, regulatory region DNA binding |
| Gene Ontology ID |
GO:0003677, GO:0010468, GO:0003700, GO:0009408, GO:0007249, GO:0007596, GO:0005515, GO:0005634, GO:0005654, GO:0005829, GO:0006351, GO:0006366, GO:0019221, GO:0045944, GO:0043565, GO:0045893, GO:0060416, GO:0007565, GO:0043374, GO:0071375, GO:0071300, GO:0071347, GO:0071356, GO:0071260, GO:0045084, GO:0010942, GO:0060333, GO:0060337, GO:0000975, GO:0071359, GO:0042512 |
| Ensembl Family |
ENSFM00500000270559 |
| InterPro ID |
IPR001346, IPR017431 |
| Ensembl Family Description |
INTERFERON REGULATORY FACTOR 1 IRF 1 |
| InterPro Term |
Interferon_reg_fac-1/2, Interferon_reg_fact_DNA-bd_dom |
| EMBL-Bank ID |
AC116366, AC003959, BC009483, BT019756, BT019755, DQ789232, CH471062, L05072, X14454, CR541713, AK314025 |
| UniGene ID |
Hs.436061, Hs.672951, Hs.665110 |
| UniProt Accession |
Q6FHN8, C9J9C5, C9JD95, P10914, Q75MZ8, F8WCM1 |
| Ensembl Protein ID |
ENSP00000405655, ENSP00000396318, ENSP00000392455, ENSP00000384406, ENSP00000245414 |
| Entrez Gene ID |
3659 |
| Gene-Disease Assocation |
LUNG CANCER, GASTRIC CANCER, CHROMOSOME 5q DELETION SYNDROME, GASTRIC CANCER, HEREDITARY DIFFUSE; HDGC |
| RefSeq ID |
NP_002189, NM_002198 |
| Description |
interferon regulatory factor 1 [Source:HGNC Symbol;Acc:6116] |
| Ensembl Gene ID |
ENSG00000125347 |
| HGNC Symbol |
IRF1 |
| Ensembl Transcript ID |
ENST00000493208, ENST00000458069, ENST00000476613, ENST00000459982, ENST00000463784, ENST00000437654, ENST00000245414, ENST00000439555, ENST00000405885, ENST00000472045 |
| Design Element |
ENST00000437654, L05072_s_at, 238725_at, 669_s_at, ENST00000245414, ENST00000459982, ENST00000439555, ENST00000472045, Hs.180559.0.A1_3p_at, ENST00000463784, ENST00000458069, 202531_at, 59777_at, g4504720_3p_at, ENST00000493208, ENST00000405885, ENST00000476613 |
| Search EB-eye |
ENSG00000125347
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