SOX4
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Homo sapiens |
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SOX4 is differentially expressed in 400 experiments: 161 organism parts: liver, thymus, ... (159 more);, 277 disease states: normal, acute myeloid leukemia, ... (275 more);, 151 cell types 528 cell lines 76 compound treatments and 87 other conditions. |
| Orthologs |
sox4a
(Danio rerio)
Sox4
(Mus musculus)
sox4b
(Danio rerio)
Q4H2S1_CIOIN
(Ciona intestinalis)
Sox14
(Drosophila melanogaster)
sox12
(Xenopus laevis)
SOX4
(Bos taurus)
SOX4
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0003677, GO:0008285, GO:0008284, GO:0003700, GO:0060070, GO:0007507, GO:0042593, GO:0005515, GO:0005737, GO:0005739, GO:0005634, GO:0043065, GO:0043066, GO:0050821, GO:0045727, GO:0031647, GO:0046826, GO:0006355, GO:0006351, GO:0045944, GO:0045893, GO:0030177, GO:0021782, GO:0035019, GO:0060412, GO:0060548, GO:0060174, GO:0048485, GO:0003215, GO:0003211, GO:0002328, GO:0042769, GO:0003289, GO:0014009, GO:0006977, GO:0031397, GO:0031018, GO:0001841, GO:0001501, GO:0060993, GO:0071333, GO:0030217, GO:0021522, GO:0021510, GO:0090263, GO:0032024, GO:0060563, GO:0000976, GO:2000761, GO:0001105, GO:0003183, GO:0003357, GO:0001077, GO:0001071, GO:0001046, GO:0035910 |
| Gene Ontology Term |
DNA binding, protein stabilization, protein binding, positive regulation of translation, regulation of transcription, DNA-dependent, cytoplasm, negative regulation of cell proliferation, transcription, DNA-dependent, positive regulation of cell proliferation, negative regulation of apoptosis, regulation of protein stability, positive regulation of apoptosis, glucose homeostasis, glial cell development, positive regulation of transcription from RNA polymerase II promoter, nucleus, heart development, somatic stem cell maintenance, canonical Wnt receptor signaling pathway, negative regulation of protein export from nucleus, positive regulation of Wnt receptor signaling pathway, positive regulation of transcription, DNA-dependent, mitochondrion, DNA damage response, detection of DNA damage, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, neural tube formation, cellular response to glucose stimulus, pro-B cell differentiation, glial cell proliferation, kidney morphogenesis, cardiac ventricle formation, spinal cord development, atrial septum primum morphogenesis, cardiac right ventricle morphogenesis, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of insulin secretion, spinal cord motor neuron differentiation, limb bud formation, skeletal system development, ventricular septum morphogenesis, sympathetic nervous system development, negative regulation of cell death, endocrine pancreas development, T cell differentiation, negative regulation of protein ubiquitination, sequence-specific DNA binding transcription factor activity, neuroepithelial cell differentiation, RNA polymerase II transcription coactivator activity, noradrenergic neuron differentiation, transcription regulatory region sequence-specific DNA binding, core promoter sequence-specific DNA binding, positive regulation of N-terminal peptidyl-lysine acetylation, mitral valve morphogenesis, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, nucleic acid binding transcription factor activity, ascending aorta morphogenesis |
| InterPro ID |
IPR000910, IPR017386 |
| InterPro Term |
HMG_HMG1/HMG2, SOX-12/11/4a |
| Ensembl Family Description |
TRANSCRIPTION FACTOR SOX 4 |
| Ensembl Family |
ENSFM00600000921562 |
| RefSeq ID |
NM_003107, NP_003098 |
| EMBL-Bank ID |
X70683, X65661, BC072668, AL136179 |
| UniGene ID |
Hs.643910, Hs.603902, Hs.702863, Hs.653479, Hs.654258, Hs.718690 |
| Entrez Gene ID |
6659 |
| Ensembl Gene ID |
ENSG00000124766 |
| Ensembl Protein ID |
ENSP00000244745, ENSP00000438412 |
| HGNC Symbol |
SOX4 |
| Description |
SRY (sex determining region Y)-box 4 [Source:HGNC Symbol;Acc:11200] |
| UniProt Accession |
Q06945 |
| Ensembl Transcript ID |
ENST00000543472, ENST00000244745 |
| Design Element |
201416_at, 213668_s_at, Hs.83484.1.S1_3p_a_at, ENST00000244745, Hs.83484.0.S3_3p_x_at, ENST00000543472, Hs.83484.0.S1_3p_at, 201418_s_at, 85332_at, g4507162_3p_a_at, 201417_at, X70683_at, 55646_at, 33131_at, Hs.83484.0.S3_3p_at |
| Search EB-eye |
ENSG00000124766
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