ACVR2A
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Homo sapiens |
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ACVR2A is differentially expressed in 286 experiments: 117 organism parts: bone marrow, lung, ... (115 more);, 150 disease states: normal, acute myeloid leukemia, ... (148 more);, 91 cell types 315 cell lines 39 compound treatments and 67 other conditions. |
| Synonyms |
ACTRII, ACVR2 |
| Orthologs |
AVR2A_CHICK
(Gallus gallus)
Acvr2a
(Rattus norvegicus)
AVR2A_BOVIN
(Bos taurus)
Q4H2P9_CIOIN
(Ciona intestinalis)
ACVR2A (2 of 2)
(Danio rerio)
acvr2a
(Danio rerio)
Acvr2a
(Mus musculus)
put
(Drosophila melanogaster)
acvr2a
(Xenopus laevis)
ACVR2A
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001245, IPR017442, IPR000719, IPR000333, IPR000472, IPR020635 |
| Gene Ontology Term |
plasma membrane, transmembrane receptor protein serine/threonine kinase activity, protein binding, cytoplasm, membrane, BMP signaling pathway, activin receptor signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway, metal ion binding, activin binding, spermatogenesis, male gonad development, protein tyrosine kinase activity, ATP binding, regulation of BMP signaling pathway, transferase activity, transferring phosphorus-containing groups, protein self-association, integral to plasma membrane, mesoderm development, receptor activity, nucleotide binding, protein serine/threonine kinase activity, positive regulation of activin receptor signaling pathway, determination of left/right symmetry, protein kinase activity, receptor signaling protein serine/threonine kinase activity, positive regulation of erythrocyte differentiation, coreceptor activity, regulation of nitric-oxide synthase activity, inhibin beta-B binding, penile erection, gastrulation with mouth forming second, positive regulation of bone mineralization, inhibin-betaglycan-ActRII complex, positive regulation of follicle-stimulating hormone secretion, embryonic skeletal system development, inhibin beta-A binding, activin receptor activity, type II, growth factor binding, Sertoli cell proliferation, positive regulation of osteoblast differentiation, response to organic substance, sperm ejaculation, protein phosphorylation, positive regulation of protein phosphorylation, transforming growth factor beta-activated receptor activity, activin-activated receptor activity, anterior/posterior pattern specification |
| Gene Ontology ID |
GO:0009952, GO:0016020, GO:0007178, GO:0007283, GO:0007368, GO:0008584, GO:0007498, GO:0030509, GO:0030510, GO:0016772, GO:0004702, GO:0004713, GO:0005524, GO:0005515, GO:0004872, GO:0043621, GO:0005737, GO:0048185, GO:0005886, GO:0005887, GO:0004672, GO:0004674, GO:0004675, GO:0005024, GO:0001934, GO:0006468, GO:0000166, GO:0046872, GO:0032924, GO:0032927, GO:0017002, GO:0015026, GO:0060011, GO:0016362, GO:0010033, GO:0048706, GO:0030501, GO:0042713, GO:0048187, GO:0048186, GO:0043084, GO:0019838, GO:0046881, GO:0001702, GO:0045669, GO:0045648, GO:0050999, GO:0034673 |
| InterPro Term |
Activin_rcpt, Prot_kinase_cat_dom, Activin_II/TGFBeta-II_recpt, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Ensembl Family |
ENSFM00500000269790 |
| Ensembl Family Description |
TYPE 2 PRECURSOR EC_2.7.11.30 TYPE II TYPE II RECEPTOR II |
| Description |
activin A receptor, type IIA [Source:HGNC Symbol;Acc:173] |
| Entrez Gene ID |
92 |
| EMBL-Bank ID |
AK301629, X62381, X63128, D31770, CH471058, BC067418, BC067417, BC069707, AC009480, M93415, AK314124 |
| Ensembl Protein ID |
ENSP00000241416, ENSP00000384338, ENSP00000439988 |
| UniGene ID |
Hs.608447, Hs.594664, Hs.470174 |
| RefSeq ID |
NM_001616, NP_001607 |
| UniProt Accession |
P27037, B4DWQ2 |
| Ensembl Gene ID |
ENSG00000121989 |
| HGNC Symbol |
ACVR2A |
| Ensembl Transcript ID |
ENST00000495775, ENST00000487959, ENST00000462659, ENST00000465329, ENST00000404590, ENST00000241416, ENST00000535787 |
| Design Element |
ENST00000465329, ENST00000487959, ENST00000495775, g10862696_3p_a_at, ENST00000535787, ENST00000404590, 228416_at, ENST00000462659, 53468_at, ENST00000241416, 62358_at, 205327_s_at, 35162_s_at, M93415_at, Hs.33412.0.A1_3p_at |
| Search EB-eye |
ENSG00000121989
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