TNFSF10
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Homo sapiens |
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TNFSF10 is differentially expressed in 334 experiments: 160 organism parts: prostate, trachea, ... (158 more);, 223 disease states: normal, prostate carcinoma, ... (221 more);, 112 cell types 460 cell lines 62 compound treatments and 76 other conditions. |
| Synonyms |
CD253, Apo-2L, TL2, TRAIL |
| Orthologs |
Tnfsf10
(Mus musculus)
tnfsf10l2
(Danio rerio)
E1BE56_BOVIN
(Bos taurus)
F1NF17_CHICK
(Gallus gallus)
Tnfsf10
(Rattus norvegicus)
TNFSF10
(Xenopus laevis)
B4XH66_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0016020, GO:0007165, GO:0007267, GO:0005625, GO:0005615, GO:0005515, GO:0005576, GO:0006915, GO:0006919, GO:0006917, GO:0006955, GO:0005887, GO:0005102, GO:0005125, GO:0005164, GO:0046872, GO:0008624, GO:0008633, GO:0043123 |
| Gene Ontology Term |
protein binding, apoptosis, extracellular space, membrane, tumor necrosis factor receptor binding, metal ion binding, activation of caspase activity, extracellular region, receptor binding, cell-cell signaling, cytokine activity, soluble fraction, induction of apoptosis, integral to plasma membrane, immune response, signal transduction, positive regulation of I-kappaB kinase/NF-kappaB cascade, activation of pro-apoptotic gene products, induction of apoptosis by extracellular signals |
| InterPro ID |
IPR006052, IPR017355 |
| InterPro Term |
TNF_family, TNF_ligand_10/11 |
| Ensembl Family |
ENSFM00500000271744 |
| Ensembl Family Description |
TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 TNF RELATED APOPTOSIS INDUCING LIGAND TRAIL CD253 ANTIGEN |
| EMBL-Bank ID |
AC016938, EU183231, AC007919, EF064708, BT019564, CR456895, CH471052, DQ848564, AY312579, BC032722, AK312742, AK296085, U37518, U57059 |
| RefSeq ID |
NM_001190942, NM_001190943, NP_001177871, NP_003801, NM_003810 |
| UniProt Accession |
A1Y9B3, P50591, Q6IBA9, Q6JSD9 |
| Ensembl Protein ID |
ENSP00000241261, ENSP00000389931, ENSP00000404008 |
| HGNC Symbol |
TNFSF10 |
| Description |
tumor necrosis factor (ligand) superfamily, member 10 [Source:HGNC Symbol;Acc:11925] |
| UniGene ID |
Hs.478275, Hs.619712 |
| Entrez Gene ID |
8743 |
| Ensembl Gene ID |
ENSG00000121858 |
| Ensembl Transcript ID |
ENST00000494851, ENST00000430881, ENST00000241261, ENST00000420541, ENST00000472804, ENST00000466777 |
| Design Element |
1715_at, 214329_x_at, g1336207_3p_a_at, ENST00000430881, 202688_at, ENST00000420541, ENST00000472804, U37518_at, ENST00000466777, Hs.301527.0.A1_3p_x_at, 202687_s_at, ENST00000494851, 214329_3p_x_at, ENST00000241261 |
| Search EB-eye |
ENSG00000121858
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