APAF1
close
Please copy/paste those URLs into your code to get same results in machine-readable formats:
|
Homo sapiens |
|
APAF1 is differentially expressed in 275 experiments: 121 organism parts: lung, skeletal muscle, ... (119 more);, 208 disease states: normal, glioblastoma, ... (206 more);, 93 cell types 350 cell lines 43 compound treatments and 69 other conditions. |
| Synonyms |
APAF-1, CED4 |
| Orthologs |
apaf1
(Danio rerio)
Apaf1
(Mus musculus)
PRP4
(Saccharomyces cerevisiae)
APAF1
(Gallus gallus)
APAF1
(Bos taurus)
D3ZA56_RAT
(Rattus norvegicus)
apaf1
(Xenopus laevis)
APAF_CANFA
(Canis familiaris)
(Compare orthologs)
|
| Gene Ontology Term |
cytosol, protein binding, apoptosis, cytoplasm, apoptotic protease activator activity, intracellular, Golgi apparatus, activation of caspase activity, activation of caspase activity by cytochrome c, soluble fraction, identical protein binding, ATP binding, defense response, multicellular organismal development, nucleus, caspase activator activity, nucleotide binding, nervous system development, DNA fragmentation involved in apoptotic nuclear change, brain development, neuron apoptosis, regulation of apoptosis, neural tube closure, apoptosome, forebrain development, ADP binding, induction of apoptosis by intracellular signals, positive regulation of peptidase activity |
| InterPro Term |
WD40_repeat_dom, WD40_repeat, Disease_R, WD40_repeat_2, NB-ARC, CARD, Apoptotic_pept-activating_1, G-protein_beta_WD-40_rep, WD40_repeat_subgr |
| InterPro ID |
IPR001680, IPR017986, IPR000767, IPR019781, IPR019782, IPR002182, IPR020472, IPR001315, IPR017251 |
| Gene Ontology ID |
GO:0008656, GO:0008635, GO:0016505, GO:0007275, GO:0007399, GO:0007420, GO:0051402, GO:0042802, GO:0005622, GO:0005625, GO:0005524, GO:0005515, GO:0006915, GO:0006919, GO:0006952, GO:0005737, GO:0005634, GO:0005829, GO:0005794, GO:0042981, GO:0000166, GO:0006309, GO:0008629, GO:0030900, GO:0043293, GO:0001843, GO:0043531, GO:0010952 |
| Ensembl Family |
ENSFM00250000004726 |
| Ensembl Family Description |
APOPTOTIC PROTEASE ACTIVATING FACTOR 1 APAF 1 |
| UniGene ID |
Hs.674000, Hs.552567, Hs.713249, Hs.728891 |
| EMBL-Bank ID |
AJ133644, AJ133645, AJ133643, AF149794, AC011248, CH471054, AJ243010, AJ243008, AJ243007, AJ243009, AJ243004, AJ243003, AJ243006, AF248734, AJ243005, AJ243011, AJ243048, AJ243107, BC136532, AF134397, AB007873, AF013263, AC013283, BC136531, AB103079 |
| RefSeq ID |
NP_001151, NM_181861, NP_037361, NP_863651, NP_863659, NP_863658, NM_013229, NM_181868, NM_181869, NM_001160 |
| Ensembl Protein ID |
ENSP00000349862, ENSP00000334558, ENSP00000448161, ENSP00000448165, ENSP00000448449, ENSP00000450175, ENSP00000448826, ENSP00000341830, ENSP00000449791, ENSP00000353059 |
| Description |
apoptotic peptidase activating factor 1 [Source:HGNC Symbol;Acc:576] |
| HGNC Symbol |
APAF1 |
| UniProt Accession |
O14727, F8VNZ0, C9JLV4 |
| Entrez Gene ID |
317 |
| Ensembl Transcript ID |
ENST00000339433, ENST00000547743, ENST00000551964, ENST00000547045, ENST00000549007, ENST00000555047, ENST00000333991, ENST00000552929, ENST00000359972, ENST00000547666, ENST00000357310, ENST00000550527, ENST00000552268, ENST00000546491 |
| Ensembl Gene ID |
ENSG00000120868 |
| Design Element |
211553_x_at, ENST00000551964, ENST00000547743, ENST00000546491, g4929486_3p_a_at, ENST00000359972, ENST00000339433, ENST00000547045, ENST00000547666, ENST00000552268, 37227_at, ENST00000333991, ENST00000357310, 204859_s_at, ENST00000555047, ENST00000549007, ENST00000550527, g13506924_3p_a_at, 211554_s_at, g7108332_3p_a_at, ENST00000552929 |
| Search EB-eye |
ENSG00000120868
|
 Show more
properties
|
|
