SOCS2
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Homo sapiens |
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SOCS2 is differentially expressed in 358 experiments: 140 organism parts: prostate, uterus, ... (138 more);, 172 disease states: normal, chronic myelogenous leukemia, ... (170 more);, 115 cell types 455 cell lines 57 compound treatments and 76 other conditions. |
| Synonyms |
CIS2, SSI-2, SOCS-2, STATI2, Cish2, SSI2 |
| Orthologs |
Q4H2S6_CIOIN
(Ciona intestinalis)
Q8AYA6_CHICK
(Gallus gallus)
socs2
(Danio rerio)
SOCS2_BOVIN
(Bos taurus)
Socs2
(Rattus norvegicus)
socs2
(Xenopus laevis)
Q1ZZT6_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
regulation of signal transduction, insulin-like growth factor receptor binding, regulation of JAK-STAT cascade, protein binding, cytoplasm, negative regulation of signal transduction, anti-apoptosis, aging, SH3/SH2 adaptor activity, regulation of cell growth, JAK-STAT cascade, prolactin receptor binding, growth hormone receptor binding, JAK pathway signal transduction adaptor activity, response to peptide hormone stimulus, growth hormone receptor signaling pathway, response to estradiol stimulus, cellular response to hormone stimulus, intracellular signal transduction |
| InterPro Term |
SH2, SOCS_C |
| Gene Ontology ID |
GO:0009966, GO:0009968, GO:0007259, GO:0007568, GO:0005515, GO:0006916, GO:0005737, GO:0005159, GO:0005070, GO:0046425, GO:0001558, GO:0060396, GO:0008269, GO:0005131, GO:0005148, GO:0032870, GO:0043434, GO:0032355, GO:0035556 |
| InterPro ID |
IPR001496, IPR000980 |
| Ensembl Family |
ENSFM00500000271698 |
| Ensembl Family Description |
SUPPRESSOR OF CYTOKINE SIGNALING 2 SOCS 2 CYTOKINE INDUCIBLE SH2 2 CIS 2 |
| EMBL-Bank ID |
AK313165, AB004903, AF132441, AB006966, AK297662, BC010399, AK290546, AF037989, CH471054, AF020590, AC012085 |
| Ensembl Protein ID |
ENSP00000339428, ENSP00000448611, ENSP00000448709, ENSP00000448815, ENSP00000445369, ENSP00000449227, ENSP00000447902, ENSP00000447161, ENSP00000442898 |
| Ensembl Gene ID |
ENSG00000120833 |
| Description |
suppressor of cytokine signaling 2 [Source:HGNC Symbol;Acc:19382] |
| RefSeq ID |
NM_003877, NP_003868 |
| Entrez Gene ID |
8835 |
| UniProt Accession |
O14508, B4DMW5, A8K3D1, F8VU91, F8VRV3, F8VS53 |
| HGNC Symbol |
SOCS2 |
| Ensembl Transcript ID |
ENST00000340600, ENST00000548091, ENST00000536696, ENST00000551556, ENST00000551883, ENST00000547229, ENST00000549887, ENST00000539385, ENST00000549510, ENST00000549206, ENST00000549122, ENST00000548537 |
| UniGene ID |
Hs.594327, Hs.485572, Hs.609535, Hs.612640 |
| Design Element |
ENST00000536696, ENST00000549206, ENST00000551883, 203372_s_at, g4507262_3p_at, ENST00000549510, ENST00000549122, 48876_at, ENST00000548537, ENST00000549887, 203373_at, 44795_at, 38994_at, ENST00000340600, ENST00000551556, ENST00000539385, g2443360_3p_a_at, ENST00000547229, ENST00000548091 |
| Search EB-eye |
ENSG00000120833
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