FOXO3
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Homo sapiens |
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FOXO3 is differentially expressed in 347 experiments: 135 organism parts: bone marrow, cerebellum, ... (133 more);, 221 disease states: normal, cervical carcinoma, ... (219 more);, 116 cell types 464 cell lines 48 compound treatments and 84 other conditions. |
| Synonyms |
AF6q21, FKHRL1, FOXO2, FOXO3A |
| Orthologs |
Foxo3
(Mus musculus)
foxo
(Drosophila melanogaster)
FOXO3
(Bos taurus)
FOXO3
(Gallus gallus)
foxo3a
(Danio rerio)
foxo3b
(Danio rerio)
Foxo3
(Rattus norvegicus)
ENSCING00000016777
(Ciona intestinalis)
ENSCING00000016781
(Ciona intestinalis)
foxo3
(Xenopus laevis)
FOXO3
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0009888, GO:0048015, GO:0003677, GO:0003690, GO:0008286, GO:0008301, GO:0003700, GO:0003705, GO:0009790, GO:0008543, GO:0007389, GO:0042593, GO:0051090, GO:0005624, GO:0005515, GO:0006915, GO:0006917, GO:0005737, GO:0005634, GO:0005654, GO:0005667, GO:0005829, GO:0006974, GO:0019901, GO:0000122, GO:0042127, GO:0006355, GO:0006351, GO:0045944, GO:0001556, GO:0043565, GO:0045893, GO:0030330, GO:0048011, GO:0045648, GO:0001547, GO:0001542, GO:0001544 |
| Gene Ontology Term |
cytosol, pattern specification process, embryo development, DNA binding, protein binding, apoptosis, regulation of transcription, DNA-dependent, cytoplasm, double-stranded DNA binding, regulation of cell proliferation, transcription, DNA-dependent, DNA bending activity, insulin receptor signaling pathway, membrane fraction, glucose homeostasis, fibroblast growth factor receptor signaling pathway, transcription factor binding, DNA damage response, signal transduction by p53 class mediator, sequence-specific DNA binding, induction of apoptosis, positive regulation of transcription from RNA polymerase II promoter, tissue development, protein kinase binding, nucleus, oocyte maturation, transcription factor complex, nucleoplasm, negative regulation of transcription from RNA polymerase II promoter, response to DNA damage stimulus, positive regulation of transcription, DNA-dependent, positive regulation of erythrocyte differentiation, ovulation from ovarian follicle, nerve growth factor receptor signaling pathway, antral ovarian follicle growth, initiation of primordial ovarian follicle growth, sequence-specific DNA binding transcription factor activity, phosphatidylinositol-mediated signaling, regulation of sequence-specific DNA binding transcription factor activity, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity |
| InterPro ID |
IPR001766 |
| Ensembl Family Description |
FORKHEAD BOX O |
| InterPro Term |
TF_fork_head |
| Ensembl Family |
ENSFM00250000000963 |
| Ensembl Gene ID |
ENSG00000118689 |
| EMBL-Bank ID |
BC020227, AK301304, AL391646, BC068552, BC021224, AF032886, CH471051, AJ001590, AJ001589, AL096818, AL365509 |
| Ensembl Protein ID |
ENSP00000339527, ENSP00000385824, ENSP00000446316, ENSP00000442607 |
| Entrez Gene ID |
2309 |
| RefSeq ID |
NM_201559, NM_001455, NP_001446, NR_026718, NP_963853 |
| UniGene ID |
Hs.592126, Hs.220950 |
| Description |
forkhead box O3 [Source:HGNC Symbol;Acc:3821] |
| UniProt Accession |
O43524, B4DVZ6, F5H7C9 |
| HGNC Symbol |
FOXO3 |
| Ensembl Transcript ID |
ENST00000406360, ENST00000343882, ENST00000540898, ENST00000540258 |
| Design Element |
210655_s_at, 47893_s_at, g4106722_3p_a_at, 224891_at, 34740_at, Hs.274468.0.S1_3p_s_at, Hs.214783.0.S1_3p_at, 224889_at, ENST00000343882, Hs.14845.0.A2_3p_a_at, ENST00000406360, 224889_3p_at, 49469_at, 49651_at, Hs.214783.0.S1_3p_x_at, 217399_3p_s_at, ENST00000540258, 204132_s_at, 217399_s_at, ENST00000540898, Hs.214783.0.S2_3p_at, 204131_s_at |
| Search EB-eye |
ENSG00000118689
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