STK11
close
Please copy/paste those URLs into your code to get same results in machine-readable formats:
|
Homo sapiens |
|
STK11 is differentially expressed in 270 experiments: 132 organism parts: liver, testis, ... (130 more);, 196 disease states: normal, chronic myelogenous leukemia, ... (194 more);, 80 cell types 366 cell lines 35 compound treatments and 74 other conditions. |
| Synonyms |
LKB1, PJS |
| Orthologs |
STK11
(Gallus gallus)
Stk11
(Rattus norvegicus)
stk11
(Danio rerio)
STK11
(Bos taurus)
Stk11
(Mus musculus)
ENSCING00000006359
(Ciona intestinalis)
lkb1
(Drosophila melanogaster)
SAK1
(Saccharomyces cerevisiae)
TOS3
(Saccharomyces cerevisiae)
stk11
(Xenopus laevis)
STK11
(Canis familiaris)
(Compare orthologs)
|
| InterPro ID |
IPR002290, IPR001245, IPR017442, IPR000719, IPR020635 |
| Gene Ontology Term |
establishment of cell polarity, cytosol, negative regulation of cell growth, protein binding, cytoplasm, negative regulation of cell proliferation, protein complex, membrane, cell cycle arrest, protein tyrosine kinase activity, insulin receptor signaling pathway, positive regulation of transforming growth factor beta receptor signaling pathway, glucose homeostasis, regulation of fatty acid biosynthetic process, response to ionizing radiation, ATP binding, cell cycle, magnesium ion binding, nucleus, canonical Wnt receptor signaling pathway, spermatid development, regulation of Wnt receptor signaling pathway, nucleotide binding, regulation of cell growth, protein serine/threonine kinase activity, axonogenesis, tissue homeostasis, response to DNA damage stimulus, autophagy, protein kinase activity, mitochondrion, positive regulation of axonogenesis, energy reserve metabolic process, negative regulation of epithelial cell proliferation involved in prostate gland development, protein kinase activator activity, LRR domain binding, vasculature development, regulation of fatty acid oxidation, response to peptide hormone stimulus, response to lipid, positive regulation of gluconeogenesis, p53 binding, regulation of protein kinase B signaling cascade, Golgi localization, response to glucagon stimulus, protein heterooligomerization, protein autophosphorylation, protein phosphorylation, positive regulation of protein phosphorylation, signal transduction by p53 class mediator resulting in induction of apoptosis, anoikis |
| Ensembl Family |
ENSFM00320000100166 |
| Gene Ontology ID |
GO:0008286, GO:0008285, GO:0016020, GO:0060070, GO:0007049, GO:0007050, GO:0010212, GO:0007286, GO:0007409, GO:0042304, GO:0030511, GO:0042593, GO:0004713, GO:0005524, GO:0005515, GO:0006914, GO:0005737, GO:0005739, GO:0005634, GO:0005829, GO:0006974, GO:0004672, GO:0004674, GO:0001934, GO:0006468, GO:0000166, GO:0046777, GO:0000287, GO:0001894, GO:0043234, GO:0001558, GO:0030111, GO:0030010, GO:0030308, GO:0051291, GO:0002039, GO:0046320, GO:0050772, GO:0001944, GO:0045722, GO:0051896, GO:0006112, GO:0033993, GO:0051645, GO:0043434, GO:0033762, GO:0060770, GO:0030275, GO:0030295, GO:0072332, GO:0043276 |
| InterPro Term |
Prot_kinase_cat_dom, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Description |
serine/threonine kinase 11 [Source:HGNC Symbol;Acc:11389] |
| Ensembl Protein ID |
ENSP00000324856, ENSP00000384275 |
| EMBL-Bank ID |
U63333, BC019334, AF032984, AF055325, AF055326, AF055327, AF055321, AF055322, AF055323, AF055324, AF055320, CH471139, AK314858, AC004221, AF035625, BC007981, AC011544 |
| UniProt Accession |
Q15831, Q9NS52 |
| Entrez Gene ID |
6794 |
| Ensembl Gene ID |
ENSG00000118046 |
| Gene-Disease Assocation |
TESTICULAR TUMORS, PEUTZ-JEGHERS SYNDROME; PJS |
| HGNC Symbol |
STK11 |
| RefSeq ID |
NP_000446, NM_000455 |
| UniGene ID |
Hs.515005 |
| Ensembl Transcript ID |
ENST00000326873, ENST00000405031 |
| Ensembl Family Description |
SERINE/THREONINE KINASE STK11 EC_2.7.11.1 LIVER KINASE B1 LKB1 |
| Design Element |
204292_x_at, ENST00000326873, ENST00000405031, g4507270_3p_s_at, 41657_at, 86312_at, 231017_at, Hs.155647.0.S1_3p_at |
| Search EB-eye |
ENSG00000118046
|
 Show more
properties
|
|
