RPS6KA1
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Homo sapiens |
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RPS6KA1 is differentially expressed in 251 experiments: 131 organism parts: bone marrow, spleen, ... (129 more);, 212 disease states: normal, acute myeloid leukemia, ... (210 more);, 90 cell types 388 cell lines 29 compound treatments and 62 other conditions. |
| Synonyms |
RSK, RSK1, HU-1 |
| Orthologs |
Rps6ka1
(Rattus norvegicus)
KS6AA_CHICK
(Gallus gallus)
rps6ka1
(Danio rerio)
A4IFF4_BOVIN
(Bos taurus)
ENSCING00000005582
(Ciona intestinalis)
Rps6ka1
(Mus musculus)
rps6ka1
(Xenopus laevis)
RPS6KA1
(Canis familiaris)
S6kII
(Drosophila melanogaster)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR017892, IPR001245, IPR017442, IPR000719, IPR000961, IPR020635, IPR016239, IPR010440 |
| Gene Ontology Term |
Toll signaling pathway, cytosol, phosphotransferase activity, alcohol group as acceptor, caspase inhibitor activity, innate immune response, membrane, protein tyrosine kinase activity, stress-activated MAPK cascade, ATP binding, magnesium ion binding, axon guidance, synaptic transmission, transferase activity, transferring phosphorus-containing groups, spindle, nucleotide binding, protein serine/threonine kinase activity, nucleoplasm, signal transduction, lipopolysaccharide biosynthetic process, negative regulation of caspase activity, protein kinase activity, intracellular protein kinase cascade, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, toll-like receptor 3 signaling pathway, nerve growth factor receptor signaling pathway, toll-like receptor 2 signaling pathway, MyD88-dependent toll-like receptor signaling pathway, protein phosphorylation, MyD88-independent toll-like receptor signaling pathway, toll-like receptor 1 signaling pathway |
| Gene Ontology ID |
GO:0016020, GO:0008063, GO:0007165, GO:0007243, GO:0007268, GO:0007411, GO:0051403, GO:0016773, GO:0016772, GO:0004713, GO:0005524, GO:0005654, GO:0005829, GO:0005819, GO:0004672, GO:0004674, GO:0043154, GO:0006468, GO:0043027, GO:0000166, GO:0000287, GO:0009103, GO:0045087, GO:0048011, GO:0034142, GO:0034138, GO:0034134, GO:0002755, GO:0002224, GO:0002756, GO:0034130 |
| InterPro Term |
Pkinase_C, AGC-kinase_C, Prot_kinase_cat_dom, Ribosomal_S6_kinase_II, LipoPS_kinase, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Ensembl Family |
ENSFM00570000851006 |
| Ensembl Family Description |
RIBOSOMAL S6 KINASE ALPHA EC_2.7.11.1 MAP KINASE ACTIVATED KINASE MAPK ACTIVATED KINASE MAPKAP KINASE MAPKAPK RIBOSOMAL S6 KINASE RSK |
| UniProt Accession |
Q15418, Q5SVM7, Q5SVM6, B7Z2K7, E9PMM7, E9PPN6, E9PPC1, E9PRI4, E9PAN7, E9PGT4, E9PGT3, A6NND1 |
| Ensembl Protein ID |
ENSP00000363283, ENSP00000363281, ENSP00000363279, ENSP00000363278, ENSP00000363277, ENSP00000403548, ENSP00000383967, ENSP00000355831, ENSP00000436990, ENSP00000431651, ENSP00000433039, ENSP00000435412, ENSP00000432281, ENSP00000434616 |
| Description |
ribosomal protein S6 kinase, 90kDa, polypeptide 1 [Source:HGNC Symbol;Acc:10430] |
| RefSeq ID |
NP_001006666, NP_002944, NM_001006665, NM_002953 |
| EMBL-Bank ID |
BC014966, AL627313, AK292722, AK315730, CH471059, AK299007, AK294818, AL109743, L07597 |
| Entrez Gene ID |
6195 |
| UniGene ID |
Hs.149957 |
| Ensembl Gene ID |
ENSG00000117676 |
| HGNC Symbol |
RPS6KA1 |
| Ensembl Transcript ID |
ENST00000403732, ENST00000530607, ENST00000526792, ENST00000438977, ENST00000530003, ENST00000524436, ENST00000526040, ENST00000366866, ENST00000530305, ENST00000531382, ENST00000488985, ENST00000531113, ENST00000525525, ENST00000374166, ENST00000374163, ENST00000374164, ENST00000374168, ENST00000374162, ENST00000525582, ENST00000527264, ENST00000529454, ENST00000474934 |
| Design Element |
g4506732_3p_at, ENST00000366866, ENST00000527264, 1127_at, ENST00000525582, ENST00000530305, ENST00000526040, ENST00000403732, ENST00000529454, ENST00000526792, 203379_at, ENST00000525525, ENST00000531113, ENST00000488985, ENST00000530607, ENST00000438977, ENST00000374162, ENST00000374163, ENST00000474934, ENST00000374164, L07597_at, ENST00000374166, ENST00000374168, ENST00000531382, ENST00000530003, ENST00000524436 |
| Search EB-eye |
ENSG00000117676
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