ARHGEF2
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Homo sapiens |
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ARHGEF2 is differentially expressed in 335 experiments: 138 organism parts: liver, pancreas, ... (136 more);, 208 disease states: normal, prostate carcinoma, ... (206 more);, 96 cell types 427 cell lines 48 compound treatments and 77 other conditions. |
| Synonyms |
P40, KIAA0651, GEF-H1, LFP40 |
| Orthologs |
Arhgef2
(Mus musculus)
arhgef1
(Danio rerio)
ARHGEF2 (1 of 2)
(Danio rerio)
ROM1
(Saccharomyces cerevisiae)
A6H6Z8_BOVIN
(Bos taurus)
Arhgef2
(Rattus norvegicus)
ROM2
(Saccharomyces cerevisiae)
CG10188
(Drosophila melanogaster)
NP_001001456.1
(Xenopus laevis)
ARHG2_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, plasma membrane, establishment of mitotic spindle orientation, cell division, microtubule binding, protein binding, apoptosis, cytoskeleton, cytoplasm, regulation of cell proliferation, intracellular, Golgi apparatus, intracellular protein transport, tight junction, metal ion binding, negative regulation of microtubule depolymerization, cell morphogenesis, actin filament organization, cell junction, regulation of Rho protein signal transduction, guanyl-nucleotide exchange factor activity, cell cycle, small GTPase mediated signal transduction, spindle, microtubule, cell projection, regulation of small GTPase mediated signal transduction, mitosis, Rho guanyl-nucleotide exchange factor activity, positive regulation of NF-kappaB transcription factor activity, negative regulation of neurogenesis, zinc ion binding, neuronal cell body, Rac GTPase binding, Rac guanyl-nucleotide exchange factor activity, Rho GTPase binding, induction of apoptosis by extracellular signals, nerve growth factor receptor signaling pathway, dendritic shaft, ruffle membrane, intracellular signal transduction |
| Gene Ontology ID |
GO:0008270, GO:0008017, GO:0007015, GO:0007026, GO:0007049, GO:0007067, GO:0007264, GO:0005923, GO:0051301, GO:0051056, GO:0051092, GO:0005622, GO:0005515, GO:0006915, GO:0005737, GO:0006886, GO:0005886, GO:0005874, GO:0005856, GO:0005829, GO:0005819, GO:0005794, GO:0042995, GO:0005085, GO:0005089, GO:0050768, GO:0000902, GO:0043025, GO:0000132, GO:0046872, GO:0042127, GO:0030054, GO:0035023, GO:0048011, GO:0008624, GO:0030676, GO:0048365, GO:0032587, GO:0043198, GO:0017048, GO:0035556 |
| InterPro ID |
IPR000219, IPR001849, IPR002219 |
| Ensembl Family Description |
RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2 GUANINE NUCLEOTIDE EXCHANGE FACTOR H1 GEF H1 |
| InterPro Term |
Pleckstrin_homology, DH-domain, Prot_Kinase_C-like_PE/DAG-bd |
| Ensembl Family |
ENSFM00250000000618 |
| EMBL-Bank ID |
AL355388, BC020567, AL512715, BT007407, X15610, U72206, CH471121, AB014551, AF486838, AK304548 |
| Ensembl Gene ID |
ENSG00000116584 |
| Entrez Gene ID |
9181 |
| Ensembl Protein ID |
ENSP00000401713, ENSP00000315325, ENSP00000357299, ENSP00000357298, ENSP00000314787, ENSP00000354837, ENSP00000438911 |
| Description |
Rho/Rac guanine nucleotide exchange factor (GEF) 2 [Source:HGNC Symbol;Acc:682] |
| UniProt Accession |
Q92974, D3DVA5, Q5VY93, B7Z977, F5H3H5 |
| RefSeq ID |
NP_001155856, NP_001155855, NM_001162384, NM_001162383, NM_004723, NP_004714 |
| HGNC Symbol |
ARHGEF2 |
| Ensembl Transcript ID |
ENST00000543433, ENST00000487755, ENST00000462460, ENST00000476273, ENST00000465079, ENST00000471589, ENST00000313695, ENST00000313667, ENST00000495070, ENST00000497907, ENST00000477754, ENST00000470874, ENST00000435736, ENST00000470975, ENST00000470541, ENST00000474428, ENST00000361247, ENST00000368316, ENST00000368315 |
| UniGene ID |
Hs.730719 |
| Design Element |
ENST00000462460, 235595_at, Hs2.337774.2.S1_3p_s_at, 1554783_s_at, ENST00000476273, ENST00000435736, g4758671_3p_s_at, ENST00000361247, g12653008_3p_s_at, ENST00000477754, ENST00000497907, ENST00000313667, U72206_at, ENST00000474428, ENST00000543433, 209435_s_at, 40099_at, ENST00000313695, ENST00000368316, ENST00000368315, ENST00000465079, ENST00000495070, 75496_at, Hs.105739.0.A1_3p_at, ENST00000470874, 40101_g_at, 207629_s_at, ENST00000470975, ENST00000471589, ENST00000470541, ENST00000487755 |
| Search EB-eye |
ENSG00000116584
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