CDKN1B
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Homo sapiens |
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CDKN1B is differentially expressed in 281 experiments: 89 organism parts: cerebellum, amygdala, ... (87 more);, 159 disease states: normal, control, ... (157 more);, 82 cell types 347 cell lines 47 compound treatments and 71 other conditions. |
| Synonyms |
P27KIP1, KIP1 |
| Orthologs |
cdkn1b
(Danio rerio)
CDKN1B
(Gallus gallus)
CDKN1B (1 of 3)
(Danio rerio)
cdkn1bl
(Danio rerio)
Cdkn1b
(Mus musculus)
A6QLS3_BOVIN
(Bos taurus)
Cdkn1b
(Rattus norvegicus)
CDN1B_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cyclin-dependent protein kinase activity, cytosol, negative regulation of cell growth, phosphorylation, negative regulation of transcription, DNA-dependent, protein binding, cytoplasm, negative regulation of cell proliferation, positive regulation of cell proliferation, autophagic cell death, mitotic cell cycle, regulation of cyclin-dependent protein kinase activity, negative regulation of apoptosis, cell cycle arrest, potassium ion transport, G1 phase of mitotic cell cycle, fibroblast growth factor receptor signaling pathway, induction of apoptosis, cell cycle, sensory perception of sound, G1/S transition of mitotic cell cycle, nucleus, positive regulation of microtubule polymerization, kinase activity, endosome, nucleoplasm, cell cycle checkpoint, S phase of mitotic cell cycle, cyclin-dependent protein kinase inhibitor activity, negative regulation of epithelial cell proliferation, negative regulation of cyclin-dependent protein kinase activity, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, negative regulation of epithelial cell proliferation involved in prostate gland development, negative regulation of kinase activity, negative regulation of cellular component movement, positive regulation of protein catabolic process, inner ear development, protein kinase inhibitor activity, cellular response to lithium ion, cellular response to antibiotic, negative regulation of phosphorylation, nerve growth factor receptor signaling pathway, protein phosphatase binding, transforming growth factor beta receptor, cytoplasmic mediator activity, phosphatidylinositol-mediated signaling, cellular response to organic cyclic compound |
| Gene Ontology ID |
GO:0048015, GO:0008285, GO:0008284, GO:0007049, GO:0007050, GO:0016310, GO:0016301, GO:0008543, GO:0007605, GO:0004693, GO:0000080, GO:0000082, GO:0000084, GO:0000079, GO:0000075, GO:0004861, GO:0005515, GO:0006917, GO:0005737, GO:0005634, GO:0005654, GO:0005829, GO:0048102, GO:0005768, GO:0006813, GO:0050680, GO:0043066, GO:0031116, GO:0045736, GO:0000278, GO:0045892, GO:0030308, GO:0048011, GO:0048839, GO:0051271, GO:0042326, GO:0004860, GO:0006977, GO:0019903, GO:0045732, GO:0033673, GO:0071407, GO:0071285, GO:0071236, GO:0060770, GO:0005072 |
| InterPro Term |
CDI |
| InterPro ID |
IPR003175 |
| Ensembl Family Description |
CYCLIN DEPENDENT KINASE INHIBITOR 1B CYCLIN DEPENDENT KINASE INHIBITOR P27 P27KIP1 |
| Ensembl Family |
ENSFM00500000271503 |
| EMBL-Bank ID |
BC001971, CR457399, AF480891, BT019553, BT019554, AF213700, U10906, CH471094, AK312461, AK298335, S76988, S76986, AB451291, AB451423, AC008115 |
| Ensembl Protein ID |
ENSP00000407597, ENSP00000379629, ENSP00000228872, ENSP00000442344 |
| UniProt Accession |
P46527, Q9UH60, Q6I9V6, B4DPH2, E7ES52 |
| UniGene ID |
Hs.238990, Hs.628402 |
| Entrez Gene ID |
1027 |
| Description |
cyclin-dependent kinase inhibitor 1B (p27, Kip1) [Source:HGNC Symbol;Acc:1785] |
| Ensembl Gene ID |
ENSG00000111276 |
| HGNC Symbol |
CDKN1B |
| RefSeq ID |
NM_004064, NP_004055 |
| Ensembl Transcript ID |
ENST00000442489, ENST00000477087, ENST00000228872, ENST00000535674, ENST00000396340 |
| Gene-Disease Assocation |
MULTIPLE ENDOCRINE NEOPLASIA, TYPE IV; MEN4 |
| Design Element |
52535_s_at, 33848_r_at, 209112_at, ENST00000228872, ENST00000477087, g12805034_3p_at, ENST00000396340, 2034_s_at, ENST00000535674, 33847_s_at, ENST00000442489 |
| Search EB-eye |
ENSG00000111276
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