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CCND1 Homo sapiens
CCND1 is differentially expressed in 147 experiments [153 up/151 dn]: 24 organism parts: peripheral blood [0 up/2 dn], bone marrow [0 up/2 dn], ...; 37 disease states: normal [5 up/10 dn], epilepsy [0 up/1 dn], ...; 38 cell types, 36 cell lines, 33 compound treatments and 20 other conditions.
Synonyms BCL1, CCND1, PRAD1, hCG_2016647, cyclin D1
Orthologs CCND1_RAT (Rattus norvegicus)  cyd-1 (Caenorhabditis elegans)  Ccnd1 (Mus musculus)  (Compare orthologs)
InterPro Term Cyclin, Cyclin D, Cyclin, A/B/D/E, Cyclin, N-terminal, Cyclin-related
Diseases Colorectal cancer, susceptibility to, von Hippel-Lindau disease, modification of
GO Terms G1/S DNA damage checkpoint, G1/S transition of mitotic cell cycle, Leydig cell differentiation, cell division, cyclin-dependent protein kinase regulator activity
Uniprot P24385  Q5MGB2  Q6FI00  Q9H014 
Search EB-eye ENSG00000110092
REST API
Expression Summary
254 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
10
5
Monocyte Cell type
3
1
None Compound treatment
1
3
A549 Cell line
3
Homo sapiens Organism
1
2
Stromal cell Cell type
1
2
PC3 Cell line
2
Peripheral blood Organism part
2
Fibroblast Cell type
2
Macaca mulatta Organism
2
Pan troglodytes Organism
2
Bone marrow Organism part
2
MK886 Compound treatment
2
Caco-2 Cell line
2
Placebo Compound treatment
1
1
Primary Disease staging
2
Lymph node metastasis Disease staging
2
SW480 Cell line
1
1
SW620 Cell line
1
1
FLAP Compound treatment
2
Control Compound treatment
2
17beta-estradiol Compound treatment
1
1
Lymph node Organism part
2
Dendritic cell Cell type
2
Macrophage Cell type
2
HNRPA2B Compound treatment
2
Organism_part Material type
1
1
Cell Material type
1
1
ERalpha transfected Genotype
1
1
Lung Organism part
1
1
HL-60 Cell line
1
MCF7 Cell line
1
Synovial fluid Organism part
1
White blood cells Organism part
1
SsMCF7 Cell line
1
Kidney Organism part
1
Caudate nucleus Organism part
1
PCep4 control vector transfect... Gene modification
1
ETat plasmid transfection Gene modification
1
Endothelial cell Cell type
1
Cerebellum Organism part
1
Epilepsy Disease state
1
Clear cell sarcoma of the kidn... Disease state
1
Primary bone marrow CD34+ stem... Cell type
1
Jurkat Cell line
1
Lipopolysaccharide Compound treatment
1
T4aNxMx Disease staging
1
KSHV latent infection Disease state
1
ERbeta transfected Genotype
1
Malignant melanoma Disease state
1
Wilms' tumor Disease state
1
Affymetrix Labeling Protocol type
1
Heregulin Compound treatment
1
Monocyte at intermediate diffe... Cell type
1
4OH-tamoxifen Compound treatment
1
Psoriatic lesional biopsy Clinical info
1
Uninvolved biopsy Clinical info
1
Endometrioid carcinoma Disease state
1
Glutamine Compound treatment
1
TIVE Cell line
1
Enzo Labeling Protocol type
1
U266 Cell line
1
HPL1 Cell line
1
T3aNxM1 Disease staging
1
Kaposi's sarcoma Disease state
1
Epidermal keratinocyte Cell type
1
SkinEthic keratinocyte Cell type
1
Colorectal adenocarcinoma Disease state
1
T47-D Cell line
1
CD3+ CD4+ CD8- CD45RA+ CD62L+ Phenotype
1
Naive T cell Cell type
1
HaCaT Cell line
1
Duchenne muscular dystrophy Disease state
1
GLI56 Cell line
1
MDA-MB-231 Cell line
1
MCF-7 Cell line
1
CD3- CD4+ CD8- Phenotype
1
Intrathymic T progenitor cell Cell type
1
Fetal bovine serum in media Growth condition
1
Kaposi's sarcoma-associated he... Infection
1
Serum starvation + thymidine b... Growth condition
1
Oligodendroglioma Disease state
1
ATM knockdown RNAi
1
MCF10A Cell line
1
Grade III Tumor grading
1
Methotrexate Compound treatment
1
Multiple myeloma Disease state
1
Lymphatic endothelial cell Cell type
1
Stage II Disease staging
1
Hypericin incubated, not irrad... Growth condition
1
Hypericin incubated, irradiate... Growth condition
1
CD3int CD4+ CD8+ Phenotype
1
Double positive thymocyte Cell type
1
Skeletal muscle Organism part
1
Vulvar intraepithelial neoplas... Disease state
1
Metastatic Disease staging
1
SCH Cell line
1
Stage I Disease staging
1
Primary gastric tumor Organism part
1
Relapse 1; ER status ER+; brai... Clinical info
1
Dimethyl sulfoxide Compound treatment
1
2-(3,4,5-trimethoxy-phenylamin... Compound treatment
1
Burkitt's lymphoma Disease state
1
BDCA3+ dendritic cell Cell type
1
Keratinocyte Cell type
1
HTERT/HPVE6 transfection Gene modification
1
LacZ control RNAi
1
Whole blood Organism part
1
Adrenal cortex cell Cell type
1
HTERT/HPVE6/HPVE7/SV40t transf... Gene modification
1
Control - interferon-gamma Compound treatment
1
CD3high CD4+ CD8- Phenotype
1
Single positive thymocyte Cell type
1
GLI60 Cell line
1
Tumor Organism part
1
Papillary thyroid carcinoma Disease state
1
Presymptomatic Disease staging
1
Adipocyte Cell type
1
Adrenal neuroblast Cell type
1
Astrocytoma Disease state
1
T84 Cell line
1
HTERT/HPVE6/HPVE7/SV40t/hRas t... Gene modification
1
Tonsil Organism part
1
Erythrocyte Cell type
1
U87 Cell line
1
U373 Cell line
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
Cancer13 Replicate
1
293 Cell line
1
Lymphoid tissue Organism part
1
Native skin Cell type
1
GLI72 Cell line
1
Uninfected control RNAi
1
Primary lymphatic endothelial ... Cell type
1
Total_RNA Material type
1
Polysome-associated RNA Material type
1
Granulocyte Cell type
1
T-cell lymphoblastic lymphoma Disease state
1
HTERT transfection Gene modification
1
IL-22 Compound treatment
1
Well-functioning transplant Clinical info
1
TaN0M0 Disease staging
1
Benign prostatic hyperplasia Disease state
1
Prostate carcinoma Disease state
1
Primary cells Cell line
1
IL-20 Compound treatment
1
Ischemic cardiomyopathy Disease state
1
Estrogen receptor 1 negative; ... Test result
1
Superficial transitional cell ... Disease state
1
Hematopoietic stem cell Cell type
1
Adipose tissue-derived stem ce... Cell type
1
Epidermal growth factor Compound treatment
1
Benign nevi Disease state
1
Mannitol Compound treatment
1
Neutrophil Cell type
1
Primary fibroblast Cell type
1
Heart Organism part
1
Benign Disease staging
1
Actinomycin D Compound treatment
1
Human papilloma virus positive Disease state
1
Human papilloma virus negative Disease state
1
IMP(1,3)A RNAi
1
Frontal cortex, superior motor... Organism part
1
Pongo pygmaea Organism
1
Johnsen score count 3.2: Serto... Histology
1
Relapse 0; ER status ER-; brai... Clinical info
1
Plasmacytoid dendritic cell Cell type
1
Unsynchronized Growth condition
1
Breast carcinoma Disease state
1
Brain Organism part
1
NCI-H929 Cell line
1
Prostate Organism part
1
Granulocyte macrophage-colony ... Compound treatment
1
Ultraviolet light Light
1
Grade II Tumor grading
1
ITS medium with albumin-bound ... Growth condition
1
ITS medium Growth condition
1
Postprandial lipid micelles in... Growth condition
1
Inter-prandial lipid micelles ... Growth condition
1
Heat-killed HL60 cell lysate Infection
1
Cyclosporin A, mycophenolate m... Clinical treatment
1
Sirolimus, mycophenolate mofet... Clinical treatment
1
Bacterial endotoxin Compound treatment
1
Invasive ductal carcinoma Histology
1
Normal Disease staging
1
Spermatocyte Cell type
1
Cardiac myocyte Cell type
1
BT474 Cell line
1
Skin Organism part
1
Monocyte-derived osteoclast Cell type
1
Female Sex
1
Male Sex
1
Seminiferous tubule Organism part
1
Selenium Compound treatment
1
Acute promyelocytic leukemia Disease state
1
U937 Cell line
1
Uterine fibroid Disease state
1
Mutant fumarate hydratase Genotype
1
Control Genotype
1
Mock RNAi
1
Lin- CD34- Phenotype
1
T4aN2M0 Disease staging
1
BL41K3 Cell line
1
BJABK3 Cell line
1
T-cell acute lymphoblastic leu... Disease state
1
All-trans retinoic acid Compound treatment
1
T3aN0Mx Disease staging
1
IL-24 Compound treatment
1
HTERT/HPVE6/HPVE7 transfection Gene modification
1
N/a Test result
1
M-CSF Compound treatment
1
ITM-ST Cell line
1
Bronchial epithelial cell Cell type
1
Nickel(II) chloride hexahydrat... Compound treatment
1
T47D Cell line
1
U0126 Compound treatment
1
SKMEL5 Cell line
1
Control - IL-1b Compound treatment
1
CodeLink Labeling Protocol type
1
Relapse 1; ER status ER-; brai... Clinical info
1
Not applicable Histology
1
Without bone lytic lesion Clinical info
1
With bone lytic lesion Clinical info
1
ERalpha/beta transfected Genotype
1
T3bN1M0 Disease staging
1
MM1 Cell line
1
Lin- CD34+ Phenotype
1
T2N0M0 Disease staging
1
Vanadium pentoxide Compound treatment
1
HMEC184 Cell line
1
Plasma cell Cell type
1
B lymphocyte Cell type
1
IL-19 Compound treatment
1
Testis Organism part
1
Crohn's disease Disease state
1
Epithelial cell Cell type
1
Typical disease progression Clinical history
1
Empty vector Gene modification
1
HGF stimulation Growth condition
1
Mercaptopurine Compound treatment
1
Pons Organism part
1
Prostate cancer Disease state
1
M2 macrophage Cell type
1
Ewing family tumor Disease state
1
Neuroblastoma Disease state
1
No induction Protocol type
1
Dermatomyositis Disease state
1
Endothelial cell + pericyte Cell type
1
Trichostatin A Compound treatment
1
Non-lung Organism part
1
Obesity Disease state
1
Acute malaria, natural infecti... Disease state
1
DMSO Vehicle
1
Expression Profiles
E-GEOD-5258: Transcription profiling of human cell lines freely cycling treated with 164 distinct small molecules - Broad Connectivity Map CMAP Set 1
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-1402: Transcription profiling of human mononuclear cells from juvenile arthritis and spondyloarthropathy patients
Experimental Factors
Disease state Organism part
Show expression profile  /  experiment details

 
E-AFMX-5: Transcription profiling of human cell lines and tissues (GNF/Novartis)
Experimental Factors
Cell type Organism part Disease state
Show expression profile  /  experiment details

 
E-MEXP-1014: Transcription profiling of two human colon cancer cell lines treated with n-3 PUFA docosahexaenoic acid for 3 different time points
Experimental Factors
Show expression profile  /  experiment details

 
E-GEOD-1563: Transcription profiling of human kidney and peripheral blood lymphocytes from kidney transplant patients
Experimental Factors
Clinical info Organism part
Show expression profile  /  experiment details

 
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