CCND1
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Homo sapiens |
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CCND1 is differentially expressed in 335 experiments: 158 organism parts: lung, prostate, ... (156 more);, 265 disease states: normal, prostate carcinoma, ... (263 more);, 105 cell types 501 cell lines 53 compound treatments and 78 other conditions. |
| Synonyms |
D11S287E, BCL1, PRAD1, U21B31 |
| Orthologs |
F1NS84_CHICK
(Gallus gallus)
Ccnd1
(Mus musculus)
F6S8K9_CIOIN
(Ciona intestinalis)
Ccnd1
(Rattus norvegicus)
CCND1_BOVIN
(Bos taurus)
ccnd1
(Danio rerio)
CycD
(Drosophila melanogaster)
ccnd1
(Xenopus laevis)
CCND1_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, cell division, cyclin-dependent protein kinase regulator activity, regulation of phosphorylation, protein binding, cytoplasm, intracellular, regulation of catalytic activity, positive regulation of cell proliferation, membrane, mitotic cell cycle, regulation of cyclin-dependent protein kinase activity, G1 phase of mitotic cell cycle, negative regulation of Wnt receptor signaling pathway, cell cycle, Wnt receptor signaling pathway, regulation of cell cycle, protein kinase binding, G1/S transition of mitotic cell cycle, nucleus, canonical Wnt receptor signaling pathway, kinase activity, response to drug, nucleoplasm, response to DNA damage stimulus, S phase of mitotic cell cycle, response to X-ray, endoplasmic reticulum unfolded protein response, response to ethanol, enzyme binding, protein kinase activity, response to corticosterone stimulus, mammary gland epithelial cell proliferation, response to magnesium ion, response to vitamin E, response to organic nitrogen, lactation, response to iron ion, response to calcium ion, positive regulation of mammary gland epithelial cell proliferation, fat cell differentiation, response to UV-A, re-entry into mitotic cell cycle, response to estrogen stimulus, organ regeneration, positive regulation of cyclin-dependent protein kinase activity, liver development, response to organic substance, negative regulation of epithelial cell differentiation, mammary gland alveolus development, cyclin-dependent protein kinase holoenzyme complex, response to steroid hormone stimulus, cellular response to organic substance, response to glucocorticoid stimulus, Leydig cell differentiation, protein phosphorylation, positive regulation of protein phosphorylation, mitotic cell cycle G1/S transition DNA damage checkpoint, response to organic cyclic compound |
| Gene Ontology ID |
GO:0016055, GO:0008284, GO:0016020, GO:0060070, GO:0007049, GO:0016538, GO:0010165, GO:0016301, GO:0051301, GO:0042325, GO:0042493, GO:0000080, GO:0000082, GO:0000084, GO:0000079, GO:0005622, GO:0005515, GO:0005737, GO:0005634, GO:0005654, GO:0030968, GO:0005829, GO:0006974, GO:0004672, GO:0050790, GO:0019901, GO:0001934, GO:0006468, GO:0019899, GO:0051726, GO:0000278, GO:0030178, GO:0045471, GO:0010243, GO:0010039, GO:0010033, GO:0051384, GO:0051412, GO:0007595, GO:0048545, GO:0014070, GO:0043627, GO:0030857, GO:0031100, GO:0045737, GO:0001889, GO:0000307, GO:0000320, GO:0031571, GO:0051592, GO:0033598, GO:0033601, GO:0070141, GO:0071310, GO:0045444, GO:0060749, GO:0033197, GO:0032026, GO:0033327 |
| InterPro Term |
Cyclin-like, Cyclin_N, Cyclin_C, Cyclin_A/B/D/E |
| InterPro ID |
IPR006671, IPR014400, IPR004367, IPR013763 |
| Ensembl Family Description |
G1/S SPECIFIC CYCLIN |
| Ensembl Family |
ENSFM00250000001580 |
| EMBL-Bank ID |
AK313136, CR542099, BC001501, X77754, L09054, M73554, X59798, CR536538, BC025302, BC023620, AF511593, BT019844, BT019845, M74092, AY830112, Z23022, BC000076, CH471076, M64349, BC014078, AP001888, AK299044 |
| UniProt Accession |
P24385, Q9H014, Q6FI00, Q5MGB2, B4DR06, F5H6K6, F5H4R3, F5H437 |
| Ensembl Gene ID |
ENSG00000110092 |
| Ensembl Protein ID |
ENSP00000227507, ENSP00000441863, ENSP00000437558, ENSP00000445014, ENSP00000438482 |
| UniGene ID |
Hs.523852 |
| RefSeq ID |
NM_053056, NP_444284 |
| Gene-Disease Assocation |
MYELOMA, MULTIPLE, COLORECTAL CANCER; CRC, VON HIPPEL-LINDAU SYNDROME; VHL, LEUKEMIA, CHRONIC LYMPHOCYTIC; CLL |
| Description |
cyclin D1 [Source:HGNC Symbol;Acc:1582] |
| HGNC Symbol |
CCND1 |
| Entrez Gene ID |
595 |
| Ensembl Transcript ID |
ENST00000227507, ENST00000536559, ENST00000542897, ENST00000542367, ENST00000539241, ENST00000545484, ENST00000535993 |
| Design Element |
ENST00000542367, ENST00000536559, X59798_at, 38418_at, ENST00000539241, 208712_at, 2020_at, ENST00000227507, g179364_3p_at, 208712_3p_at, ENST00000542897, g12652656_3p_s_at, ENST00000535993, ENST00000545484, g179364_3p_x_at, 208711_s_at, 2017_s_at |
| Search EB-eye |
ENSG00000110092
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