MAPK10
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Homo sapiens |
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MAPK10 is differentially expressed in 206 experiments: 153 organism parts: amygdala, liver, ... (151 more);, 163 disease states: normal, glioblastoma, ... (161 more);, 55 cell types 255 cell lines 22 compound treatments and 60 other conditions. |
| Synonyms |
PRKM10, p54bSAPK, p493F12, JNK3 |
| Orthologs |
HOG1
(Saccharomyces cerevisiae)
Q4H3A2_CIOIN
(Ciona intestinalis)
MAPK10
(Gallus gallus)
Mapk10
(Mus musculus)
mapk8b
(Danio rerio)
mapk10
(Danio rerio)
mapk8a
(Danio rerio)
mapk9
(Danio rerio)
A4FV00_BOVIN
(Bos taurus)
Mapk10
(Rattus norvegicus)
mapk10
(Xenopus laevis)
MAPK10
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001245, IPR017442, IPR000719, IPR008351, IPR020635, IPR010440 |
| Gene Ontology Term |
Toll signaling pathway, cytosol, plasma membrane, JUN kinase activity, protein binding, phosphotransferase activity, alcohol group as acceptor, JUN phosphorylation, cytoplasm, innate immune response, membrane, protein tyrosine kinase activity, MAP kinase kinase activity, stress-activated MAPK cascade, MAP kinase activity, ATP binding, transferase activity, transferring phosphorus-containing groups, nucleotide binding, protein serine/threonine kinase activity, JNK cascade, nucleoplasm, signal transduction, lipopolysaccharide biosynthetic process, protein kinase activity, mitochondrion, toll-like receptor 4 signaling pathway, toll-like receptor signaling pathway, toll-like receptor 3 signaling pathway, toll-like receptor 2 signaling pathway, MyD88-dependent toll-like receptor signaling pathway, protein phosphorylation, MyD88-independent toll-like receptor signaling pathway, regulation of sequence-specific DNA binding transcription factor activity, toll-like receptor 1 signaling pathway |
| Gene Ontology ID |
GO:0016020, GO:0008063, GO:0007165, GO:0007254, GO:0007258, GO:0051403, GO:0051090, GO:0016773, GO:0016772, GO:0004705, GO:0004707, GO:0004708, GO:0004713, GO:0005524, GO:0005515, GO:0005737, GO:0005739, GO:0005654, GO:0005886, GO:0005829, GO:0004672, GO:0004674, GO:0006468, GO:0000166, GO:0009103, GO:0045087, GO:0034142, GO:0034138, GO:0034134, GO:0002755, GO:0002224, GO:0002756, GO:0034130 |
| Ensembl Family Description |
MITOGEN ACTIVATED KINASE MAP KINASE MAPK EC_2.7.11.24 STRESS ACTIVATED KINASE C JUN N TERMINAL KINASE |
| InterPro Term |
Prot_kinase_cat_dom, JNK_MAPK, LipoPS_kinase, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Ensembl Family |
ENSFM00460000244930 |
| Ensembl Gene ID |
ENSG00000109339 |
| Ensembl Protein ID |
ENSP00000355297, ENSP00000414469, ENSP00000378598, ENSP00000378595, ENSP00000378590, ENSP00000378589, ENSP00000378586, ENSP00000422277, ENSP00000422985, ENSP00000309857, ENSP00000424755, ENSP00000424128, ENSP00000424154, ENSP00000421762, ENSP00000425654, ENSP00000352157, ENSP00000421359, ENSP00000421409, ENSP00000420987, ENSP00000423918 |
| Gene-Disease Assocation |
EPILEPTIC ENCEPHALOPATHY, LENNOX-GASTAUT TYPE |
| UniGene ID |
Hs.666725, Hs.125503, Hs.598548 |
| EMBL-Bank ID |
AC110076, BC051731, U34820, U34819, BC035057, CH471057, U07620, AC096953, AC104827, AK294125, AC104059, AK091104, AK124791, AC108054 |
| UniProt Accession |
D6R9C1, Q499Y8, A8MPV1, D6RDG1, D6RC26, D6RCB1, D6RAJ0, D6RAU3, D6RBH2, D6RFX8, D6RFZ7, D6RJF9, A8MWW6, P53779, B7Z1Z1, A6NG28, B3KR72, A8MWR3 |
| Description |
mitogen-activated protein kinase 10 [Source:HGNC Symbol;Acc:6872] |
| RefSeq ID |
NP_620448, NP_620447, NP_620446, NP_002744, NM_138980, NM_138981, NM_138982, NM_002753 |
| HGNC Symbol |
MAPK10 |
| Entrez Gene ID |
5602 |
| Ensembl Transcript ID |
ENST00000505356, ENST00000513186, ENST00000511328, ENST00000449047, ENST00000511167, ENST00000513839, ENST00000475679, ENST00000395157, ENST00000395166, ENST00000395169, ENST00000395160, ENST00000395161, ENST00000503911, ENST00000508262, ENST00000430389, ENST00000479377, ENST00000506773, ENST00000509464, ENST00000359221, ENST00000506385, ENST00000512564, ENST00000514856, ENST00000504397, ENST00000512689, ENST00000468020, ENST00000486985, ENST00000512017, ENST00000512046, ENST00000515400, ENST00000489368, ENST00000472236, ENST00000515650, ENST00000310816, ENST00000361569, ENST00000502302 |
| Design Element |
ENST00000395166, ENST00000361569, ENST00000511328, ENST00000506385, ENST00000514856, 1709_g_at, ENST00000395169, ENST00000508262, ENST00000486985, ENST00000515650, ENST00000395160, 69092_at, ENST00000395161, ENST00000511167, ENST00000475679, ENST00000430389, ENST00000512017, ENST00000513839, ENST00000479377, g4506080_3p_at, ENST00000472236, ENST00000502302, 1708_at, 237413_at, gnf1h09487_s_at, ENST00000515400, ENST00000395157, ENST00000513186, gnf1h09486_at, ENST00000505356, U07620_at, ENST00000359221, ENST00000512564, ENST00000512689, ENST00000509464, ENST00000512046, ENST00000504397, ENST00000449047, ENST00000468020, ENST00000310816, Hs.25209.0.A1_3p_at, ENST00000506773, 45430_at, ENST00000489368, ENST00000503911, 58184_at, 204813_at |
| Search EB-eye |
ENSG00000109339
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