NFKB1
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Homo sapiens |
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NFKB1 is differentially expressed in 255 experiments: 116 organism parts: brain, liver, ... (114 more);, 171 disease states: normal, control, ... (169 more);, 90 cell types 291 cell lines 41 compound treatments and 66 other conditions. |
| Synonyms |
p50, NFkappaB, p105, NF-kappaB, NFKB-p50, KBF1 |
| Orthologs |
Nfkb1
(Mus musculus)
NFKB1
(Gallus gallus)
Nfkb1
(Rattus norvegicus)
NFKB1
(Bos taurus)
Q4H348_CIOIN
(Ciona intestinalis)
Rel
(Drosophila melanogaster)
nfkb1
(Xenopus laevis)
NFKB1_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
Toll signaling pathway, cytosol, response to oxidative stress, DNA binding, negative regulation of transcription, DNA-dependent, response to copper ion, protein binding, apoptosis, regulation of transcription, DNA-dependent, cytoplasm, double-stranded DNA binding, innate immune response, protein complex, anti-apoptosis, transcription from RNA polymerase II promoter, sequence-specific DNA binding, protein dimerization activity, positive regulation of transcription from RNA polymerase II promoter, response to bacterium, nucleus, protein homodimerization activity, positive regulation of NF-kappaB transcription factor activity, nucleoplasm, negative regulation of transcription from RNA polymerase II promoter, signal transduction, positive regulation of transcription, DNA-dependent, mitochondrion, heat shock protein binding, toll-like receptor 4 signaling pathway, negative regulation of cytokine production, T cell receptor signaling pathway, positive regulation of macrophage derived foam cell differentiation, negative regulation of interleukin-12 biosynthetic process, toll-like receptor signaling pathway, I-kappaB/NF-kappaB complex, cellular response to mechanical stimulus, positive regulation of lipid storage, negative regulation of cholesterol transport, negative regulation of calcidiol 1-monooxygenase activity, positive regulation of canonical Wnt receptor signaling pathway, toll-like receptor 3 signaling pathway, inflammatory response, nerve growth factor receptor signaling pathway, toll-like receptor 2 signaling pathway, MyD88-dependent toll-like receptor signaling pathway, cellular response to interleukin-1, sequence-specific DNA binding transcription factor activity, MyD88-independent toll-like receptor signaling pathway, negative regulation of vitamin D biosynthetic process, membrane protein intracellular domain proteolysis, negative regulation of cellular protein metabolic process, transcription regulatory region DNA binding, nucleic acid binding transcription factor activity, toll-like receptor 1 signaling pathway, regulatory region DNA binding |
| Gene Ontology ID |
GO:0003677, GO:0003690, GO:0003700, GO:0008063, GO:0007165, GO:0009617, GO:0051092, GO:0042803, GO:0005515, GO:0006916, GO:0006915, GO:0005737, GO:0005739, GO:0005634, GO:0005654, GO:0005829, GO:0006979, GO:0031072, GO:0000122, GO:0006355, GO:0006366, GO:0046983, GO:0043234, GO:0045944, GO:0043565, GO:0045892, GO:0045893, GO:0046688, GO:0045087, GO:0010744, GO:0048011, GO:0034142, GO:0034138, GO:0034134, GO:0002755, GO:0006954, GO:0002224, GO:0050852, GO:0001818, GO:0044212, GO:0071347, GO:0071260, GO:0033256, GO:0090263, GO:0045083, GO:0010884, GO:0032375, GO:0010956, GO:0002756, GO:0031293, GO:0010957, GO:0032269, GO:0001071, GO:0000975, GO:0034130 |
| InterPro Term |
Ankyrin_rpt, Ankyrin_rpt-contain_dom, RHD, NF_Rel_dor, Death, IPT_TIG_rcpt |
| InterPro ID |
IPR011539, IPR002909, IPR000451, IPR000488, IPR020683, IPR002110 |
| Ensembl Gene ID |
ENSG00000109320 |
| EMBL-Bank ID |
BC033210, M55643, BC051765, CR749522, AY223820, AF213884, M58603, Z47735, Z47736, Z47737, Z47738, Z47739, Z47734, Z47749, Z47748, Z47743, Z47744, Z47741, Z47742, Z47740, Z47755, Z47751, Z47752, Z47753, Z47754, Z47750 |
| Ensembl Protein ID |
ENSP00000378297, ENSP00000226574, ENSP00000424815, ENSP00000424790, ENSP00000426147, ENSP00000420904, ENSP00000423877 |
| RefSeq ID |
NM_003998, NP_003989, NP_001158884, NM_001165412 |
| Entrez Gene ID |
4790 |
| UniGene ID |
Hs.618430 |
| UniProt Accession |
D6RDI9, D6RC45, D6RH30, D6RF93, P19838 |
| Description |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 [Source:HGNC Symbol;Acc:7794] |
| HGNC Symbol |
NFKB1 |
| Ensembl Family |
ENSFM00630001050585 |
| Ensembl Family Description |
NUCLEAR FACTOR NF KAPPA B P100 SUBUNIT DNA BINDING FACTOR KBF2 NUCLEAR FACTOR OF KAPPA LIGHT POLYPEPTIDE GENE ENHANCER IN B CELLS 2 [CONTAINS NUCLEAR FACTOR NF KAPPA B P52 |
| Ensembl Transcript ID |
ENST00000505458, ENST00000513803, ENST00000510638, ENST00000508584, ENST00000504044, ENST00000509165, ENST00000511926, ENST00000226574, ENST00000507079, ENST00000394820, ENST00000502367 |
| Design Element |
70160_at, ENST00000509165, ENST00000507079, ENST00000226574, 209239_at, 38438_at, ENST00000502367, ENST00000511926, 1377_at, ENST00000510638, ENST00000513803, g189179_3p_at, ENST00000394820, M58603_at, ENST00000504044, 1378_g_at, ENST00000508584, ENST00000505458 |
| Search EB-eye |
ENSG00000109320
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