ALOX12
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Homo sapiens |
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ALOX12 is differentially expressed in 158 experiments: 60 organism parts: tongue, esophagus, ... (58 more);, 115 disease states: normal, lung adenocarcinoma, ... (113 more);, 43 cell types 82 cell lines 14 compound treatments and 63 other conditions. |
| Synonyms |
12S-LOX |
| Orthologs |
Alox12
(Mus musculus)
F1MFA8_BOVIN
(Bos taurus)
Alox12
(Rattus norvegicus)
ALOX12
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, oxidoreductase activity, positive regulation of caspase activity, leukotriene biosynthetic process, protein binding, iron ion binding, cytoplasm, cellular component movement, positive regulation of cell proliferation, positive regulation of gene expression, negative regulation of apoptosis, metal ion binding, anti-apoptosis, positive regulation of apoptosis, sarcolemma, fatty acid oxidation, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, positive regulation of cell growth, superoxide anion generation, positive regulation of cell adhesion, positive regulation of cell killing, lipoxygenase activity, positive regulation of endothelial cell migration, arachidonate 12-lipoxygenase activity, positive regulation of mitochondrial depolarization, negative regulation of cell killing, hepoxilin-epoxide hydrolase activity, positive regulation of endothelial cell differentiation, oxidation-reduction process, reactive oxygen species metabolic process |
| Gene Ontology ID |
GO:0010628, GO:0008284, GO:0016491, GO:0042383, GO:0016702, GO:0005506, GO:0005515, GO:0006916, GO:0006928, GO:0005737, GO:0005829, GO:0055114, GO:0043065, GO:0043066, GO:0019395, GO:0019370, GO:0046872, GO:0043280, GO:0030307, GO:0016165, GO:0010595, GO:0004052, GO:0042554, GO:0031343, GO:0031342, GO:0051901, GO:0045785, GO:0047977, GO:0045603, GO:0072593 |
| InterPro ID |
IPR001024, IPR001885, IPR013819 |
| InterPro Term |
LipOase_LH2, LipOase_C, LipOase_mml |
| Ensembl Family Description |
ARACHIDONATE LIPOXYGENASE |
| Ensembl Family |
ENSFM00250000000705 |
| EMBL-Bank ID |
M87004, M62982, AY527817, BC069557, AF143883, M35418, S68587, D12638, M58704 |
| HGNC Symbol |
ALOX12 |
| Description |
arachidonate 12-lipoxygenase [Source:HGNC Symbol;Acc:429] |
| UniGene ID |
Hs.654431 |
| UniProt Accession |
P18054 |
| Ensembl Protein ID |
ENSP00000251535, ENSP00000384466 |
| Ensembl Gene ID |
ENSG00000108839 |
| RefSeq ID |
NM_000697, NP_000688 |
| Entrez Gene ID |
239 |
| Ensembl Transcript ID |
ENST00000480801, ENST00000251535, ENST00000406228 |
| Design Element |
207206_s_at, ENST00000480801, ENST00000251535, g4502050_3p_a_at, 35124_at, M62982_at, ENST00000406228 |
| Search EB-eye |
ENSG00000108839
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