DKK1
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Homo sapiens |
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DKK1 is differentially expressed in 257 experiments: 101 organism parts: placenta, lung, ... (99 more);, 174 disease states: normal, prostate carcinoma, ... (172 more);, 95 cell types 459 cell lines 41 compound treatments and 69 other conditions. |
| Synonyms |
DKK-1, SK |
| Orthologs |
Q8UUX3_CHICK
(Gallus gallus)
Q4H3Q2_CIOIN
(Ciona intestinalis)
dkk1b
(Danio rerio)
Dkk1
(Mus musculus)
DKK1
(Bos taurus)
Dkk1
(Rattus norvegicus)
dkk1
(Xenopus laevis)
DKK1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0048019, GO:0008083, GO:0007165, GO:0007275, GO:0007492, GO:0030514, GO:0005615, GO:0005515, GO:0005576, GO:0004871, GO:0005886, GO:0050750, GO:0000904, GO:0000122, GO:0001706, GO:0001707, GO:0030111, GO:0030178, GO:0060323, GO:0060325, GO:0048642, GO:0030900, GO:0031333, GO:0032526, GO:0090090, GO:0090082, GO:0001942, GO:0030326, GO:0033137, GO:0090244, GO:0002090 |
| Gene Ontology Term |
plasma membrane, mesoderm formation, receptor antagonist activity, cell morphogenesis involved in differentiation, protein binding, extracellular space, endoderm formation, growth factor activity, extracellular region, negative regulation of Wnt receptor signaling pathway, signal transducer activity, endoderm development, multicellular organismal development, negative regulation of BMP signaling pathway, regulation of Wnt receptor signaling pathway, negative regulation of transcription from RNA polymerase II promoter, signal transduction, head morphogenesis, hair follicle development, forebrain development, response to retinoic acid, negative regulation of peptidyl-serine phosphorylation, embryonic limb morphogenesis, negative regulation of canonical Wnt receptor signaling pathway, negative regulation of skeletal muscle tissue development, face morphogenesis, negative regulation of protein complex assembly, Wnt receptor signaling pathway involved in somitogenesis, regulation of receptor internalization, low-density lipoprotein particle receptor binding, positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway |
| InterPro ID |
IPR006796 |
| InterPro Term |
Dickkopf_N |
| Ensembl Family Description |
DICKKOPF RELATED 1 PRECURSOR DICKKOPF 1 DKK 1 1 |
| Ensembl Family |
ENSFM00500000272568 |
| EMBL-Bank ID |
BC001539, AB020315, CH471083, AK314902, AF261158, AF261157, AY359005, AF177394, AF127563 |
| Ensembl Protein ID |
ENSP00000363081 |
| UniGene ID |
Hs.40499 |
| HGNC Symbol |
DKK1 |
| RefSeq ID |
NM_012242, NP_036374 |
| Ensembl Gene ID |
ENSG00000107984 |
| Entrez Gene ID |
22943 |
| Description |
dickkopf homolog 1 (Xenopus laevis) [Source:HGNC Symbol;Acc:2891] |
| UniProt Accession |
O94907 |
| Ensembl Transcript ID |
ENST00000373970, ENST00000467359, ENST00000476752, ENST00000494277 |
| Design Element |
ENST00000467359, g7110718_3p_at, ENST00000373970, 35977_at, 204602_at, ENST00000494277, ENST00000476752 |
| Search EB-eye |
ENSG00000107984
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