GLI3
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Homo sapiens |
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GLI3 is differentially expressed in 262 experiments: 137 organism parts: lung, liver, ... (135 more);, 159 disease states: normal, prostate carcinoma, ... (157 more);, 95 cell types 409 cell lines 32 compound treatments and 74 other conditions. |
| Synonyms |
PAPA, GCPS, PAP-A, PAPA1, PPDIV, PHS, PAPB, ACLS |
| Orthologs |
GLI3
(Bos taurus)
GLI3
(Gallus gallus)
gli3
(Danio rerio)
Gli3
(Rattus norvegicus)
Q4H3F1_CIOIN
(Ciona intestinalis)
Gli3
(Mus musculus)
gli3
(Xenopus laevis)
GLI3
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
hindgut morphogenesis, cytosol, pattern specification process, transcriptional repressor complex, negative regulation of transcription, DNA-dependent, protein binding, regulation of transcription, DNA-dependent, cytoplasm, beta-catenin binding, regulation of cell proliferation, intracellular, negative regulation of cell proliferation, embryonic digestive tract development, transcription, DNA-dependent, negative regulation of smoothened signaling pathway, developmental growth, negative regulation of apoptosis, metal ion binding, embryonic morphogenesis, proximal/distal pattern formation, smoothened signaling pathway, intracellular membrane-bounded organelle, histone deacetylase binding, positive regulation of neuroblast proliferation, sequence-specific DNA binding, axon guidance, positive regulation of transcription from RNA polymerase II promoter, nucleus, protein processing, heart development, regulation of gene expression, regulation of cell differentiation, histone acetyltransferase binding, chromatin binding, negative regulation of transcription from RNA polymerase II promoter, negative regulation of cell differentiation, cilium, brain development, mediator complex, positive regulation of transcription, DNA-dependent, nucleolus, central nervous system development, zinc ion binding, regulation of apoptosis, dorsal/ventral pattern formation, negative regulation of alpha-beta T cell differentiation, optic nerve morphogenesis, smoothened signaling pathway involved in spinal cord motor neuron cell fate specification, oligodendrocyte differentiation, subpallium development, limb morphogenesis, frontal suture morphogenesis, smoothened signaling pathway involved in dorsal/ventral neural tube patterning, in utero embryonic development, kidney development, telencephalon development, branching involved in ureteric bud morphogenesis, pallium development, negative thymic T cell selection, positive regulation of chondrocyte differentiation, limb development, camera-type eye morphogenesis, inner ear development, forebrain development, mammary gland development, melanocyte differentiation, positive regulation of protein import into nucleus, embryonic skeletal system morphogenesis, anatomical structure development, anatomical structure formation involved in morphogenesis, branching morphogenesis of a tube, positive regulation of alpha-beta T cell differentiation, metanephros development, smoothened signaling pathway involved in ventral spinal cord interneuron specification, embryonic digit morphogenesis, embryonic digestive tract morphogenesis, negative regulation of neuron differentiation, artery development, anterior semicircular canal development, lateral semicircular canal development, neural tube development, lung development, mammary gland specification, camera-type eye development, positive regulation of osteoblast differentiation, neuron fate commitment, palate development, tube development, odontogenesis of dentine-containing tooth, tongue development, embryonic limb morphogenesis, negative regulation of canonical Wnt receptor signaling pathway, spinal cord dorsal/ventral patterning, forebrain dorsal/ventral pattern formation, sequence-specific DNA binding transcription factor activity, T cell differentiation in thymus, sagittal suture morphogenesis, forebrain radial glial cell differentiation, cerebral cortex radial glia guided migration, lambdoid suture morphogenesis, cell differentiation involved in kidney development, lateral ganglionic eminence cell proliferation, thymocyte apoptosis, anterior/posterior pattern specification |
| Gene Ontology ID |
GO:0003682, GO:0009953, GO:0009954, GO:0009952, GO:0008285, GO:0008270, GO:0010468, GO:0003700, GO:0008013, GO:0016592, GO:0016485, GO:0007224, GO:0007389, GO:0007442, GO:0007420, GO:0007411, GO:0007417, GO:0005929, GO:0007507, GO:0048566, GO:0048589, GO:0048598, GO:0005622, GO:0005515, GO:0005730, GO:0005737, GO:0005634, GO:0042826, GO:0002052, GO:0005829, GO:0042981, GO:0043066, GO:0000122, GO:0046872, GO:0042127, GO:0006355, GO:0006351, GO:0043231, GO:0045596, GO:0045595, GO:0045944, GO:0043565, GO:0045879, GO:0045892, GO:0045893, GO:0035035, GO:0017053, GO:0060364, GO:0060594, GO:0060021, GO:0060173, GO:0048856, GO:0048839, GO:0048709, GO:0048704, GO:0042307, GO:0048754, GO:0042475, GO:0048646, GO:0048663, GO:0048593, GO:0048557, GO:0042733, GO:0030900, GO:0030879, GO:0090090, GO:0043010, GO:0001701, GO:0045665, GO:0045669, GO:0001822, GO:0046639, GO:0046638, GO:0043586, GO:0001658, GO:0001656, GO:0021915, GO:0021798, GO:0021775, GO:0021776, GO:0030318, GO:0030324, GO:0030326, GO:0060875, GO:0060873, GO:0060840, GO:0060831, GO:0021631, GO:0021513, GO:0021543, GO:0021544, GO:0021537, GO:0045060, GO:0035108, GO:0033077, GO:0032332, GO:0035295, GO:0060367, GO:0060366, GO:0022018, GO:0021801, GO:0021861, GO:0061005, GO:0070242 |
| InterPro Term |
Znf_C2H2-like, Znf_C2H2 |
| Ensembl Family Description |
ZINC FINGER |
| Ensembl Family |
ENSFM00400000131745 |
| InterPro ID |
IPR007087, IPR015880 |
| EMBL-Bank ID |
AC005028, AC005026, AC005158, BC117168, M20674, BC113616, M57609, AC073852, CH236951, AJ250408 |
| Gene-Disease Assocation |
POLYDACTYLY, PREAXIAL IV, POLYDACTYLY, POSTAXIAL, TYPE A1, HYPOTHALAMIC HAMARTOMAS, GREIG CEPHALOPOLYSYNDACTYLY SYNDROME; GCPS, ACROCALLOSAL SYNDROME; ACLS, PALLISTER-HALL SYNDROME; PHS |
| Entrez Gene ID |
2737 |
| UniGene ID |
Hs.707641, Hs.21509 |
| UniProt Accession |
C9J9N4, P10071, F8WEV4 |
| Description |
GLI family zinc finger 3 [Source:HGNC Symbol;Acc:4319] |
| Ensembl Protein ID |
ENSP00000407963, ENSP00000379258, ENSP00000406135 |
| RefSeq ID |
NP_000159, NM_000168 |
| Ensembl Gene ID |
ENSG00000106571 |
| HGNC Symbol |
GLI3 |
| Ensembl Transcript ID |
ENST00000395925, ENST00000479210, ENST00000437480, ENST00000464291, ENST00000428534, ENST00000448703 |
| Design Element |
Hs.21509.0.A1_3p_at, 60798_at, 227376_at, 1569342_at, ENST00000464291, ENST00000479210, ENST00000395925, 59780_s_at, ENST00000428534, 40358_at, g13518031_3p_at, ENST00000437480, 205201_at, ENST00000448703, M57609_at |
| Search EB-eye |
ENSG00000106571
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