HSPB1
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Homo sapiens |
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HSPB1 is differentially expressed in 317 experiments: 151 organism parts: bone marrow, cerebellum, ... (149 more);, 223 disease states: normal, control, ... (221 more);, 98 cell types 427 cell lines 41 compound treatments and 76 other conditions. |
| Synonyms |
Hsp25, Hs.76067, HSP27, HSP28 |
| Orthologs |
E1BEL7_BOVIN
(Bos taurus)
Hspb1
(Rattus norvegicus)
F6RRK4_CIOIN
(Ciona intestinalis)
Hspb1
(Mus musculus)
F1P593_CHICK
(Gallus gallus)
l(2)efl
(Drosophila melanogaster)
hspb1
(Danio rerio)
hspb1
(Xenopus laevis)
HSPB1_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
angiogenesis, cytosol, plasma membrane, proteasome complex, protein binding, cytoskeleton, cytoplasm, cellular component movement, intracellular, negative regulation of protein kinase activity, negative regulation of apoptosis, RNA metabolic process, response to stress, regulation of translational initiation, insoluble fraction, anti-apoptosis, response to unfolded protein, soluble fraction, contractile fiber, spindle, nucleus, cell death, regulation of I-kappaB kinase/NF-kappaB cascade, cell surface, ubiquitin binding, Z disc, protein kinase C inhibitor activity, mRNA metabolic process, blood vessel endothelial cell migration, response to virus, negative regulation of phosphorylation, positive regulation of tumor necrosis factor biosynthetic process, positive regulation of interleukin-1 beta production, negative regulation of protein serine/threonine kinase activity, protein kinase C delta binding, endothelial cell chemotaxis, cellular response to vascular endothelial growth factor stimulus |
| Gene Ontology ID |
GO:0008219, GO:0016070, GO:0009986, GO:0008426, GO:0005626, GO:0005622, GO:0005625, GO:0005515, GO:0006916, GO:0006928, GO:0006950, GO:0005737, GO:0005634, GO:0005886, GO:0005856, GO:0005829, GO:0005819, GO:0006986, GO:0000502, GO:0043066, GO:0043130, GO:0043122, GO:0006469, GO:0006446, GO:0043292, GO:0001525, GO:0030018, GO:0016071, GO:0009615, GO:0042326, GO:0042535, GO:0032731, GO:0043534, GO:0035767, GO:0072568, GO:0071901, GO:0035924 |
| InterPro ID |
IPR001436, IPR002068 |
| InterPro Term |
Hsp20, Alpha-crystallin/HSP |
| Ensembl Family |
ENSFM00500000270924 |
| Ensembl Family Description |
HEAT SHOCK BETA 1 HSPB1 HEAT SHOCK 27 KDA HSP 27 |
| EMBL-Bank ID |
Z23090, CR536489, X54079, AK311894, X16477, BC014920, U90906, BC012292, BC073768, BT019888, BC012768, AB020027, AC006388, CH471220, BC000510, CR407614, S74571, L39370, AK296890, DQ379985 |
| Ensembl Protein ID |
ENSP00000414357, ENSP00000405285, ENSP00000248553, ENSP00000406545 |
| UniGene ID |
Hs.726398 |
| RefSeq ID |
NM_001540, NP_001531 |
| UniProt Accession |
C9J3N8, P04792, B4DL87, F8WE04 |
| HGNC Symbol |
HSPB1 |
| Ensembl Gene ID |
ENSG00000106211 |
| Entrez Gene ID |
3315 |
| Description |
heat shock 27kDa protein 1 [Source:HGNC Symbol;Acc:5246] |
| Gene-Disease Assocation |
NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE IIB; HMN2B, CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2F; CMT2F |
| Ensembl Transcript ID |
ENST00000447574, ENST00000429938, ENST00000432276, ENST00000248553 |
| Design Element |
g4996892_3p_x_at, 201841_3p_s_at, ENST00000432276, ENST00000447574, 201841_s_at, 36785_at, ENST00000429938, g4996892_3p_a_at, 63673_at, ENST00000248553, Z23090_at |
| Search EB-eye |
ENSG00000106211
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