CAV1
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Homo sapiens |
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CAV1 is differentially expressed in 312 experiments: 193 organism parts: lung, bone marrow, ... (191 more);, 274 disease states: normal, glioblastoma, ... (272 more);, 113 cell types 577 cell lines 35 compound treatments and 70 other conditions. |
| Synonyms |
CAV |
| Orthologs |
cav1
(Danio rerio)
CAV1_BOVIN
(Bos taurus)
F6YRU0_CIOIN
(Ciona intestinalis)
Cav1
(Mus musculus)
F1NTW2_CHICK
(Gallus gallus)
Cav1
(Rattus norvegicus)
cav1
(Xenopus laevis)
CAV1_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
focal adhesion, cytosol, plasma membrane, protein localization, negative regulation of JAK-STAT cascade, endoplasmic reticulum, protein binding, flagellum, cytoplasm, intracellular, syntaxin binding, cell cortex, negative regulation of cell proliferation, protein complex, negative regulation of signal transduction, Golgi membrane, protein homooligomerization, kinase binding, Golgi apparatus, MAPKKK cascade, structural molecule activity, lipid particle, maintenance of protein location in cell, receptor binding, blood coagulation, membrane raft, response to hypoxia, membrane fraction, cholesterol binding, soluble fraction, basolateral plasma membrane, protein oligomerization, response to nutrient, cholesterol homeostasis, triglyceride metabolic process, cellular calcium ion homeostasis, microtubule polymerization, regulation of smooth muscle contraction, integral to plasma membrane, positive regulation of microtubule polymerization, negative regulation of BMP signaling pathway, positive regulation of endocytosis, peptidase activator activity, lipid storage, endosome, response to drug, cytoplasmic vesicle, perinuclear region of cytoplasm, apical plasma membrane, integral to membrane of membrane fraction, negative regulation of MAP kinase activity, calcium ion transport, cholesterol transport, basal plasma membrane, negative regulation of transcription from RNA polymerase II promoter, cell surface, negative regulation of MAPKKK cascade, response to gamma radiation, skeletal muscle tissue development, response to mechanical stimulus, calcium ion homeostasis, caveola, mitochondrion, vesicle organization, negative regulation of cytokine-mediated signaling pathway, positive regulation of peptidyl-serine phosphorylation, cholesterol efflux, negative regulation of protein binding, regulation of peptidase activity, leukocyte migration, lactation, response to calcium ion, response to progesterone stimulus, regulation of nitric-oxide synthase activity, inactivation of MAPK activity, negative regulation of tyrosine phosphorylation of Stat5 protein, membrane depolarization, mammary gland development, positive regulation of canonical Wnt receptor signaling pathway, positive regulation of anti-apoptosis, response to estrogen stimulus, vasculogenesis, protein complex scaffold, negative regulation of nitric oxide biosynthetic process, positive regulation of calcium ion transport into cytosol, regulation of blood coagulation, interspecies interaction between organisms, vasoconstriction, SNARE binding, positive regulation of signal transduction, acrosomal membrane, negative regulation of peptidyl-serine phosphorylation, negative regulation of epithelial cell differentiation, nitric oxide homeostasis, mammary gland involution, positive regulation of metalloenzyme activity, T cell costimulation, regulation of fatty acid metabolic process, cytosolic calcium ion homeostasis, negative regulation of canonical Wnt receptor signaling pathway, caveola assembly, cellular response to starvation, response to glucocorticoid stimulus, negative regulation of endothelial cell proliferation, nitric-oxide synthase binding, positive regulation of vasoconstriction, nitric oxide metabolic process, endocytic vesicle membrane, positive regulation of peptidase activity, receptor internalization involved in canonical Wnt receptor signaling pathway |
| Gene Ontology ID |
GO:0009968, GO:0008285, GO:0009986, GO:0009925, GO:0016050, GO:0010332, GO:0008104, GO:0016504, GO:0009612, GO:0016323, GO:0016324, GO:0005938, GO:0005901, GO:0005925, GO:0051259, GO:0007584, GO:0051260, GO:0007596, GO:0007519, GO:0042493, GO:0030514, GO:0048471, GO:0042632, GO:0005622, GO:0005624, GO:0005625, GO:0005515, GO:0006940, GO:0005737, GO:0005739, GO:0006874, GO:0005886, GO:0005887, GO:0005829, GO:0005811, GO:0005783, GO:0005794, GO:0005768, GO:0015485, GO:0005102, GO:0055074, GO:0005198, GO:0006816, GO:0006641, GO:0046426, GO:0032507, GO:0019905, GO:0019900, GO:0019915, GO:0019861, GO:0031116, GO:0000165, GO:0000122, GO:0000139, GO:0046785, GO:0000299, GO:0043234, GO:0031410, GO:0045807, GO:0001666, GO:0043407, GO:0043409, GO:0045121, GO:0030301, GO:0009967, GO:0010524, GO:0060056, GO:0052547, GO:0051384, GO:0007595, GO:0042310, GO:0042524, GO:0048554, GO:0043627, GO:0002080, GO:0030879, GO:0030857, GO:0031295, GO:0032570, GO:0090090, GO:0001937, GO:0001960, GO:0046209, GO:0000188, GO:0000149, GO:0045768, GO:0019217, GO:0032947, GO:0051899, GO:0044419, GO:0001570, GO:0051480, GO:0045907, GO:0070836, GO:0051592, GO:0030193, GO:0033344, GO:0033484, GO:0050900, GO:0033138, GO:0033137, GO:0050999, GO:0050998, GO:0009267, GO:0090263, GO:0032091, GO:0045019, GO:0030666, GO:0010952, GO:2000286 |
| InterPro ID |
IPR001612 |
| Ensembl Family Description |
CAVEOLIN 1 |
| InterPro Term |
Caveolin |
| Ensembl Family |
ENSFM00500000269969 |
| EMBL-Bank ID |
AJ133269, AF095593, AF095591, AF095592, AY762103, BT007143, Z18951, BC082246, BC009685, AK290871, AC006159, CH471070, AF125348, CH236947, AB451284, AB451416 |
| Ensembl Gene ID |
ENSG00000105974 |
| UniGene ID |
Hs.74034, Hs.657308 |
| Ensembl Protein ID |
ENSP00000409541, ENSP00000339191, ENSP00000377111, ENSP00000377110, ENSP00000377113, ENSP00000389033, ENSP00000384348 |
| Description |
caveolin 1, caveolae protein, 22kDa [Source:HGNC Symbol;Acc:1527] |
| RefSeq ID |
NP_001744, NP_001166368, NP_001166367, NP_001166366, NM_001753, NM_001172897, NM_001172896, NM_001172895 |
| UniProt Accession |
Q2TNI1, C9JKI3, Q03135, E9PCT5, F8WDM7 |
| HGNC Symbol |
CAV1 |
| Entrez Gene ID |
857 |
| Gene-Disease Assocation |
LIPODYSTROPHY, CONGENITAL GENERALIZED, TYPE 3; CGL3 |
| Ensembl Transcript ID |
ENST00000393467, ENST00000393468, ENST00000393470, ENST00000341049, ENST00000451122, ENST00000456473, ENST00000489856, ENST00000405348 |
| Design Element |
ENST00000456473, ENST00000393470, ENST00000393467, g4580417_3p_s_at, ENST00000393468, 203065_s_at, ENST00000341049, 212097_at, ENST00000451122, Hs.74034.1.S1_3p_at, 36119_at, Z18951_at, ENST00000489856, ENST00000405348 |
| Search EB-eye |
ENSG00000105974
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