LIG1
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Homo sapiens |
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LIG1 is differentially expressed in 256 experiments: 102 organism parts: bone marrow, spleen, ... (100 more);, 187 disease states: normal, acute lymphoblastic leukemia, ... (185 more);, 86 cell types 260 cell lines 33 compound treatments and 71 other conditions. |
| Orthologs |
LIG1
(Gallus gallus)
Lig1
(Rattus norvegicus)
Lig1
(Mus musculus)
A4IFC8_BOVIN
(Bos taurus)
CDC9
(Saccharomyces cerevisiae)
F6Y1Y0_CIOIN
(Ciona intestinalis)
LIG1
(Danio rerio)
lig1
(Xenopus laevis)
LIG1
(Canis familiaris)
DNA-ligI
(Drosophila melanogaster)
(Compare orthologs)
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| Gene Ontology Term |
ligase activity, telomere maintenance, cell division, DNA binding, double-strand break repair via homologous recombination, nucleotide-excision repair, DNA ligase (ATP) activity, DNA repair, mitotic cell cycle, metal ion binding, double-strand break repair, ATP binding, anatomical structure morphogenesis, telomere maintenance via recombination, nucleus, DNA recombination, nucleotide binding, nucleoplasm, base-excision repair, S phase of mitotic cell cycle, DNA replication, DNA strand elongation involved in DNA replication, DNA metabolic process, nucleotide-excision repair, DNA gap filling, transcription-coupled nucleotide-excision repair, DNA ligation involved in DNA repair, DNA ligation, DNA ligase activity, telomere maintenance via semi-conservative replication |
| Gene Ontology ID |
GO:0003677, GO:0003910, GO:0009653, GO:0051301, GO:0016874, GO:0000084, GO:0005524, GO:0005634, GO:0005654, GO:0000722, GO:0000723, GO:0000724, GO:0000166, GO:0006302, GO:0006310, GO:0046872, GO:0000278, GO:0006284, GO:0006289, GO:0006281, GO:0006271, GO:0006260, GO:0006259, GO:0003909, GO:0051103, GO:0006297, GO:0006283, GO:0006266, GO:0032201 |
| Ensembl Family Description |
DNA LIGASE 1 EC_6.5.1.1 DNA LIGASE I POLYDEOXYRIBONUCLEOTIDE SYNTHASE [ATP] 1 |
| InterPro ID |
IPR000977, IPR012310, IPR012308, IPR012309 |
| Ensembl Family |
ENSFM00250000002603 |
| InterPro Term |
DNA_ligase_ATP-dep_cent, DNA_ligase_ATP-dep_C, DNA_ligase_ATP-dep_N, DNA_ligase_ATP-dep |
| UniProt Accession |
P18858, Q76GR4, B4DTU4, F5GZ28, B4E135 |
| Ensembl Gene ID |
ENSG00000105486 |
| UniGene ID |
Hs.603078, Hs.623500, Hs.1770 |
| Description |
ligase I, DNA, ATP-dependent [Source:HGNC Symbol;Acc:6598] |
| EMBL-Bank ID |
AC011466, AB103328, AK300370, CH471177, BC108318, AF527418, M36067, AK314210, AK303644 |
| Ensembl Protein ID |
ENSP00000263274, ENSP00000441531, ENSP00000438791, ENSP00000445928, ENSP00000442841 |
| Entrez Gene ID |
3978 |
| HGNC Symbol |
LIG1 |
| RefSeq ID |
NP_000225, NM_000234 |
| Ensembl Transcript ID |
ENST00000542460, ENST00000427526, ENST00000263274, ENST00000544761, ENST00000536218 |
| Design Element |
ENST00000542460, g4557718_3p_at, ENST00000536218, 202726_at, M36067_at, 1376_at, ENST00000544761, ENST00000427526, ENST00000263274, 74835_r_at |
| Search EB-eye |
ENSG00000105486
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