BBC3
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Homo sapiens |
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BBC3 is differentially expressed in 195 experiments: 85 organism parts: prostate, lung, ... (83 more);, 118 disease states: normal, acute promyelocytic leukemia, ... (116 more);, 53 cell types 125 cell lines 24 compound treatments and 59 other conditions. |
| Synonyms |
PUMA, JFY1 |
| Orthologs |
BBC3
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, protein binding, apoptosis, activation of caspase activity, determination of adult lifespan, mitochondrial outer membrane, induction of apoptosis, negative regulation of growth, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, release of sequestered calcium ion into cytosol, mitochondrion, positive regulation of thymocyte apoptosis, activation of pro-apoptotic gene products, protein insertion into mitochondrial membrane involved in induction of apoptosis, cellular response to hypoxia, induction of apoptosis by intracellular signals, release of cytochrome c from mitochondria, positive regulation of release of cytochrome c from mitochondria, reduction of endoplasmic reticulum calcium ion concentration, positive regulation of protein homooligomerization |
| Gene Ontology ID |
GO:0008340, GO:0051209, GO:0042771, GO:0005515, GO:0006915, GO:0006919, GO:0006917, GO:0005739, GO:0005741, GO:0005829, GO:0045926, GO:0008629, GO:0008633, GO:0032471, GO:0001836, GO:0001844, GO:0070245, GO:0071456, GO:0090200, GO:0032464 |
| Ensembl Family Description |
BCL 2 BINDING COMPONENT 3 P53 UP REGULATED MODULATOR OF APOPTOSIS |
| Ensembl Family |
ENSFM00500000279124 |
| EMBL-Bank ID |
AF332558, AF354655, AF354654, AF354656, U82987, CH471126, AC008532, BC136481, AK298837 |
| RefSeq ID |
NM_014417, NM_001127242, NM_001127241, NM_001127240, NP_055232, NP_001120713, NP_001120712, NP_001120714 |
| Entrez Gene ID |
27113 |
| Ensembl Gene ID |
ENSG00000105327 |
| UniProt Accession |
Q96PG8, B4DQK3, Q9BXH1, E9PAW3 |
| UniGene ID |
Hs.467020 |
| Description |
BCL2 binding component 3 [Source:HGNC Symbol;Acc:17868] |
| HGNC Symbol |
BBC3 |
| Ensembl Protein ID |
ENSP00000404503, ENSP00000300880, ENSP00000341155, ENSP00000395862 |
| Ensembl Transcript ID |
ENST00000449228, ENST00000341983, ENST00000300880, ENST00000439096 |
| Design Element |
ENST00000341983, ENST00000449228, ENST00000300880, 1700_at, U82987_at, ENST00000439096, g13591689_3p_s_at, 211692_s_at |
| Search EB-eye |
ENSG00000105327
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