ERCC2
close
Please copy/paste those URLs into your code to get same results in machine-readable formats:
|
Homo sapiens |
|
ERCC2 is differentially expressed in 245 experiments: 98 organism parts: liver, pancreas, ... (96 more);, 164 disease states: normal, Burkitt's lymphoma, ... (162 more);, 68 cell types 316 cell lines 23 compound treatments and 62 other conditions. |
| Synonyms |
XPD, MGC102762, MAG, EM9, MGC126218, MGC126219 |
| Orthologs |
Ercc2
(Mus musculus)
LOC100364929
(Rattus norvegicus)
ercc2
(Danio rerio)
RAD3
(Saccharomyces cerevisiae)
A1L590_BOVIN
(Bos taurus)
ENSCING00000003266
(Ciona intestinalis)
ENSCING00000015161
(Ciona intestinalis)
ercc2
(Xenopus laevis)
Q5SBJ3_CANFA
(Canis familiaris)
Xpd
(Drosophila melanogaster)
(Compare orthologs)
|
| Gene Ontology Term |
response to UV, response to oxidative stress, DNA binding, nucleotide-excision repair, protein binding, apoptosis, DNA repair, cytoskeleton, cytoplasm, embryonic cleavage, cell proliferation, negative regulation of apoptosis, protein N-terminus binding, chromosome segregation, ATP-dependent helicase activity, metal ion binding, nucleic acid binding, response to hypoxia, mRNA capping, transcription from RNA polymerase II promoter, multicellular organism growth, ATP binding, induction of apoptosis, positive regulation of transcription from RNA polymerase II promoter, RNA polymerase II carboxy-terminal domain kinase activity, spindle, 5'-3' DNA helicase activity, DNA-dependent ATPase activity, nucleus, ATP-dependent DNA helicase activity, aging, iron-sulfur cluster binding, nucleotide binding, post-embryonic development, transcription initiation from RNA polymerase II promoter, protein C-terminus binding, nucleoplasm, cell cycle checkpoint, extracellular matrix organization, positive regulation of transcription, DNA-dependent, protein kinase activity, transcription from RNA polymerase I promoter, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, helicase activity, nucleotide-excision repair, DNA incision, viral reproduction, in utero embryonic development, bone mineralization, hair follicle maturation, spinal cord development, transcription-coupled nucleotide-excision repair, cyclin-dependent protein kinase activating kinase holoenzyme complex, positive regulation of DNA binding, holo TFIIH complex, gene expression, UV protection, hair cell differentiation, interspecies interaction between organisms, skin development, transcription initiation from RNA polymerase I promoter, hydrolase activity, acting on acid anhydrides, hemopoietic stem cell differentiation, hair cycle process, erythrocyte maturation, positive regulation of viral transcription, SSL2-core TFIIH complex, central nervous system myelin formation, protein phosphorylation, termination of RNA polymerase I transcription, nucleotide-excision repair, DNA damage removal, transcription elongation from RNA polymerase II promoter, MMXD complex, transcription elongation from RNA polymerase I promoter, nucleobase-containing compound metabolic process |
| Gene Ontology ID |
GO:0003676, GO:0003677, GO:0008283, GO:0008353, GO:0008094, GO:0008022, GO:0008026, GO:0009411, GO:0007059, GO:0009791, GO:0007568, GO:0004386, GO:0004003, GO:0016818, GO:0000075, GO:0005524, GO:0005515, GO:0047485, GO:0006915, GO:0006917, GO:0005737, GO:0005634, GO:0005654, GO:0005856, GO:0005819, GO:0006979, GO:0004672, GO:0040016, GO:0043066, GO:0043139, GO:0006468, GO:0000166, GO:0046872, GO:0006360, GO:0006370, GO:0006366, GO:0006367, GO:0006368, GO:0006289, GO:0006281, GO:0045944, GO:0051536, GO:0006139, GO:0045893, GO:0001666, GO:0030198, GO:0035264, GO:0016032, GO:0010467, GO:0009650, GO:0060218, GO:0022405, GO:0048820, GO:0016817, GO:0005675, GO:0019907, GO:0043388, GO:0006361, GO:0001701, GO:0044419, GO:0043249, GO:0006283, GO:0043588, GO:0050434, GO:0000441, GO:0035315, GO:0033683, GO:0030282, GO:0021510, GO:0032289, GO:0006362, GO:0006363, GO:0000718, GO:0071817 |
| InterPro ID |
IPR010643, IPR010614, IPR001945, IPR000330, IPR006554, IPR006555, IPR014013, IPR013020 |
| InterPro Term |
DEAD_2, DNA_helicase_DNA-repair_Rad3, DUF1227, Helicase_ATP-dep_c2, Helicase-like_DEXD_c2, SNF2_N, XPGD_DNA_repair, Helic_SF1/SF2_ATP-bd_DinG/Rad3 |
| Ensembl Family |
ENSFM00250000002971 |
| Ensembl Family Description |
TFIIH BASAL TRANSCRIPTION FACTOR COMPLEX HELICASE XPD SUBUNIT EC_3.6.4.12 CXPD DNA EXCISION REPAIR ERCC 2 DNA REPAIR COMPLEMENTING XP D CELLS XERODERMA PIGMENTOSUM GROUP D COMPLEMENTING |
| EMBL-Bank ID |
BC110523, L47234, X52222, X52221, AY092780, AK303358, CH471126, BC108255, BT006883 |
| HGNC Symbol |
ERCC2 |
| UniGene ID |
Hs.487294 |
| Entrez Gene ID |
2068 |
| UniProt Accession |
P18074, Q7KZU6, A8MX75, B4E0F6, E7EVE9, E9PM96 |
| Ensembl Gene ID |
ENSG00000104884 |
| Ensembl Protein ID |
ENSP00000375806, ENSP00000375805, ENSP00000375804, ENSP00000375808, ENSP00000375809, ENSP00000221481, ENSP00000431229 |
| RefSeq ID |
NP_000391, NP_001124339, NM_000400, NM_001130867 |
| Description |
excision repair cross-complementing rodent repair deficiency, complementation group 2 [Source:HGNC Symbol;Acc:3434] |
| Ensembl Transcript ID |
ENST00000391944, ENST00000391941, ENST00000391942, ENST00000391945, ENST00000391940, ENST00000485403, ENST00000221481 |
| Gene-Disease Assocation |
XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP D; XPD, TRICHOTHIODYSTROPHY, PHOTOSENSITIVE; TTDP, CEREBROOCULOFACIOSKELETAL SYNDROME 2; COFS2 |
| Design Element |
ENST00000391944, 213468_at, 41095_at, ENST00000391945, ENST00000391942, ENST00000391940, ENST00000485403, ENST00000391941, ENST00000221481, 992_at, 63062_at, Hs.99987.0.S1_3p_at, 32396_f_at, Hs.184329.0.S1_3p_at, X52221_at, 32397_r_at, 235399_at |
| Search EB-eye |
ENSG00000104884
|
 Show more
properties
|
|
