AXIN1
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Homo sapiens |
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AXIN1 is differentially expressed in 172 experiments: 74 organism parts: bone marrow, liver, ... (72 more);, 104 disease states: normal, control, ... (102 more);, 55 cell types 166 cell lines 25 compound treatments and 60 other conditions. |
| Orthologs |
AXIN1
(Bos taurus)
AXIN1
(Gallus gallus)
Q4H3V5_CIOIN
(Ciona intestinalis)
Axin1
(Mus musculus)
Axin1
(Rattus norvegicus)
axin1
(Danio rerio)
Axn
(Drosophila melanogaster)
axin1
(Xenopus laevis)
AXIN1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008219, GO:0016055, GO:0009950, GO:0016023, GO:0008022, GO:0008013, GO:0060070, GO:0007165, GO:0007257, GO:0007275, GO:0016328, GO:0007368, GO:0005938, GO:0051260, GO:0030511, GO:0007628, GO:0007605, GO:0048471, GO:0042803, GO:0042802, GO:0005622, GO:0005625, GO:0014069, GO:0005515, GO:0004871, GO:0006913, GO:0006915, GO:0043621, GO:0005737, GO:0005634, GO:0005881, GO:0005886, GO:0005829, GO:0032436, GO:0046332, GO:0046330, GO:0031398, GO:0005096, GO:0019904, GO:0019901, GO:0001932, GO:0001934, GO:0050877, GO:0019899, GO:0031122, GO:0031625, GO:0043234, GO:0000209, GO:0031410, GO:0043547, GO:0045860, GO:0045893, GO:0030163, GO:0030178, GO:0032147, GO:0010800, GO:0048048, GO:0034101, GO:0060272, GO:0051443, GO:0051248, GO:0048318, GO:0048320, GO:0043623, GO:0030910, GO:0002039, GO:0030877, GO:0090090, GO:0045732, GO:0001701, GO:0044459, GO:0032947, GO:0045599, GO:0071407, GO:0035412, GO:0070412, GO:0070411, GO:0021797, GO:0033138, GO:0020027, GO:0070016, GO:0035121, GO:0071514, GO:0034747, GO:0055001, GO:0021881, GO:0034244, GO:0060823, GO:0001743, GO:0090244, GO:0071944, GO:2000060, GO:0034742, GO:0038032 |
| Gene Ontology Term |
cytosol, plasma membrane, protein binding, apoptosis, positive regulation of peptidyl-threonine phosphorylation, cytoplasm, protein catabolic process, beta-catenin binding, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, cytoplasmic microtubule organization, intracellular, cell cortex, protein complex, protein homooligomerization, positive regulation of protein ubiquitination, protein domain specific binding, neurological system process, positive regulation of transforming growth factor beta receptor signaling pathway, negative regulation of Wnt receptor signaling pathway, adult walking behavior, signal transducer activity, positive regulation of JNK cascade, soluble fraction, positive regulation of protein kinase activity, identical protein binding, GTPase activator activity, activation of JUN kinase activity, Wnt receptor signaling pathway, multicellular organismal development, sensory perception of sound, protein kinase binding, protein self-association, nucleus, protein polyubiquitination, postsynaptic density, cytoplasmic microtubule, canonical Wnt receptor signaling pathway, cell death, cytoplasmic membrane-bounded vesicle, cytoplasmic vesicle, perinuclear region of cytoplasm, protein homodimerization activity, SMAD binding, protein C-terminus binding, activation of protein kinase activity, nucleocytoplasmic transport, determination of left/right symmetry, enzyme binding, signal transduction, lateral plasma membrane, positive regulation of transcription, DNA-dependent, positive regulation of GTPase activity, dorsal/ventral axis specification, ubiquitin protein ligase binding, beta-catenin destruction complex, positive regulation of peptidyl-serine phosphorylation, armadillo repeat domain binding, negative regulation of protein metabolic process, cellular protein complex assembly, olfactory placode formation, in utero embryonic development, positive regulation of protein catabolic process, axial mesoderm development, protein complex scaffold, embryonic eye morphogenesis, axial mesoderm formation, erythrocyte homeostasis, plasma membrane part, embryonic skeletal joint morphogenesis, tail morphogenesis, negative regulation of fat cell differentiation, genetic imprinting, p53 binding, positive regulation of ubiquitin-protein ligase activity, negative regulation of canonical Wnt receptor signaling pathway, Axin-APC-beta-catenin-GSK3B complex, R-SMAD binding, hemoglobin metabolic process, I-SMAD binding, Wnt receptor signaling pathway involved in somitogenesis, muscle cell development, regulation of protein phosphorylation, canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation, optic placode formation, Wnt receptor signaling pathway involved in forebrain neuron fate commitment, positive regulation of protein phosphorylation, negative regulation of transcription elongation from RNA polymerase II promoter, cell periphery, regulation of catenin import into nucleus, APC-Axin-1-beta-catenin complex, cellular response to organic cyclic compound, positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process, forebrain anterior/posterior pattern specification, termination of G-protein coupled receptor signaling pathway |
| InterPro Term |
Regulat_G_prot_signal, DIX, Axin_b-cat-bd |
| InterPro ID |
IPR001158, IPR000342, IPR014936 |
| Ensembl Family Description |
AXIN AXIS INHIBITION |
| Ensembl Family |
ENSFM00250000001855 |
| EMBL-Bank ID |
BC044648, AC005202, BC017447, Z99754, Z69667, AE006463, AF009674 |
| RefSeq ID |
NP_851393, NM_181050, NP_003493, NM_003502 |
| Ensembl Gene ID |
ENSG00000103126 |
| UniProt Accession |
O15169, B1AH42 |
| Ensembl Protein ID |
ENSP00000346935, ENSP00000416835, ENSP00000262320 |
| UniGene ID |
Hs.592082 |
| Gene-Disease Assocation |
CAUDAL DUPLICATION ANOMALY, HEPATOCELLULAR CARCINOMA |
| Description |
axin 1 [Source:HGNC Symbol;Acc:903] |
| Entrez Gene ID |
8312 |
| HGNC Symbol |
AXIN1 |
| Ensembl Transcript ID |
ENST00000262320, ENST00000457798, ENST00000481769, ENST00000354866, ENST00000461023 |
| Design Element |
Hs.184434.0.S1_3p_at, ENST00000354866, AF009674_at, 33319_at, 212849_at, ENST00000461023, ENST00000481769, ENST00000262320, ENST00000457798 |
| Search EB-eye |
ENSG00000103126
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