ARHGEF7
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Homo sapiens |
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ARHGEF7 is differentially expressed in 311 experiments: 168 organism parts: bone marrow, liver, ... (166 more);, 216 disease states: normal, acute promyelocytic leukemia, ... (214 more);, 108 cell types 429 cell lines 35 compound treatments and 80 other conditions. |
| Synonyms |
P50, PIXB, BETA-PIX, KIAA0142, P50BP, Nbla10314, P85SPR, P85, DKFZp761K1021, P85COOL1, DKFZp686C12170, PAK3, COOL1 |
| Orthologs |
Arhgef7
(Rattus norvegicus)
Arhgef7
(Mus musculus)
ARHGEF7
(Bos taurus)
arhgef7a
(Danio rerio)
arhgef7b
(Danio rerio)
ARHGEF7
(Gallus gallus)
ENSCING00000001710
(Ciona intestinalis)
rtGEF
(Drosophila melanogaster)
CDC24
(Saccharomyces cerevisiae)
arhgef7
(Xenopus laevis)
ARHGEF7
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, negative regulation of epidermal growth factor receptor signaling pathway, protein binding, apoptosis, epidermal growth factor receptor signaling pathway, intracellular, positive regulation of apoptosis, regulation of Rho protein signal transduction, guanyl-nucleotide exchange factor activity, small GTPase mediated signal transduction, regulation of small GTPase mediated signal transduction, Rho guanyl-nucleotide exchange factor activity, nervous system development, signal transduction, induction of apoptosis by extracellular signals, nerve growth factor receptor signaling pathway, intracellular signal transduction |
| InterPro ID |
IPR001452, IPR000219, IPR011511, IPR001715, IPR001849, IPR013247 |
| Gene Ontology ID |
GO:0007173, GO:0007165, GO:0007264, GO:0007399, GO:0051056, GO:0005622, GO:0005515, GO:0006915, GO:0005829, GO:0005085, GO:0005089, GO:0043065, GO:0042059, GO:0035023, GO:0048011, GO:0008624, GO:0035556 |
| InterPro Term |
SH3_domain, Pleckstrin_homology, DH-domain, SH3_2, CH-domain, SH3_3 |
| Ensembl Family |
ENSFM00250000001135 |
| Ensembl Family Description |
RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 RAC/CDC42 GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 |
| Description |
Rho guanine nucleotide exchange factor (GEF) 7 [Source:HGNC Symbol;Acc:15607] |
| EMBL-Bank ID |
BC060776, AJ844631, AJ844629, BC033905, AB075521, AL139086, BC050521, CH471085, AB177849, AB177848, AL834228, AL353704, D63476, AL390754, AK300157, AK300272 |
| Ensembl Protein ID |
ENSP00000418067, ENSP00000418043, ENSP00000418235, ENSP00000359657, ENSP00000389890, ENSP00000218789, ENSP00000364889, ENSP00000364888, ENSP00000364893, ENSP00000364891, ENSP00000364875, ENSP00000397068, ENSP00000417596, ENSP00000325994, ENSP00000420592, ENSP00000406732, ENSP00000445384, ENSP00000438673 |
| RefSeq ID |
NM_145735, NM_003899, NP_003890, NP_001106984, NP_001106985, NP_001106983, NP_663788, NM_001113513, NM_001113512, NM_001113511 |
| Entrez Gene ID |
8874 |
| UniProt Accession |
Q5ZEZ2, Q5ZEZ3, C9JAD7, C9JDI6, Q14155, Q5W9H1, B1ALK7, B1ALK5, B1ANY6, E7ENL8, E7EU80, E7EUY6, E9PDQ5, B7Z6D9, B7Z6G2 |
| Ensembl Gene ID |
ENSG00000102606 |
| HGNC Symbol |
ARHGEF7 |
| Ensembl Transcript ID |
ENST00000469877, ENST00000426073, ENST00000467053, ENST00000426768, ENST00000218789, ENST00000375723, ENST00000375736, ENST00000375741, ENST00000375737, ENST00000375739, ENST00000449979, ENST00000478983, ENST00000370623, ENST00000478679, ENST00000545635, ENST00000483540, ENST00000466143, ENST00000483189, ENST00000491775, ENST00000544132, ENST00000317133, ENST00000491688 |
| Design Element |
ENST00000426073, 202548_s_at, ENST00000375736, ENST00000483540, ENST00000467053, D63476_at, ENST00000545635, ENST00000491688, ENST00000544132, ENST00000317133, ENST00000375737, ENST00000218789, ENST00000375739, ENST00000375723, ENST00000375741, ENST00000370623, 40828_at, 81222_at, ENST00000478679, 229642_at, Hs.117494.0.S1_3p_at, ENST00000491775, ENST00000449979, ENST00000483189, ENST00000478983, Hs.201919.0.A1_3p_at, 242999_at, g4505572_3p_a_at, ENST00000426768, Hs.172813.0.A1_3p_a_at, 202547_s_at, 69169_at, ENST00000469877, ENST00000466143 |
| Search EB-eye |
ENSG00000102606
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