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KLF5 Homo sapiens
KLF5 is differentially expressed in 125 experiments [137 up/121 dn]: 28 organism parts: liver [0 up/2 dn], skeletal muscle [1 up/1 dn], ...; 33 disease states: normal [8 up/3 dn], malignant melanoma [0 up/1 dn], ...; 27 cell types, 29 cell lines, 33 compound treatments and 18 other conditions.
Synonyms BTEB2, CKLF, IKLF, RP11-505F3.5-001, hCG_32789, KLF5
Orthologs NP_445846.2 (Rattus norvegicus)  CG12029 (Drosophila melanogaster)  F53F8.1 (Caenorhabditis elegans)  Klf5 (Mus musculus)  (Compare orthologs)
InterPro Term Zinc finger, C2H2-like, Zinc finger, C2H2-type, Zinc finger, C2H2-type/integrase, DNA-binding
GO Terms angiogenesis, intracellular, microvillus assembly, positive regulation of cell proliferation, protein binding
Uniprot Q13887  Q5T6X2 
Search EB-eye ENSG00000102554
REST API
Expression Summary
219 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
3
8
None Compound treatment
3
5
Homo sapiens Organism
4
Epithelial cell Cell type
3
Stromal cell Cell type
2
1
HL-60 Cell line
2
Endothelial cell Cell type
2
Fibroblast Cell type
1
1
FLAP Compound treatment
2
MK886 Compound treatment
2
BT-474 Cell line
2
Liver Organism part
2
HeLa Cell line
2
Estrogen receptor 1 negative; ... Test result
2
Pan troglodytes Organism
2
Uninfected Infection
2
HNRPA2B Compound treatment
2
MDA-MB-231 Cell line
1
1
Monocyte Cell type
1
1
Skeletal muscle Organism part
1
1
PC3 Cell line
1
Caudate nucleus Organism part
1
Cerebellum Organism part
1
White blood cells Organism part
1
T47D Cell line
1
SW480 Cell line
1
SW620 Cell line
1
MDA468 Cell line
1
Malignant melanoma Disease state
1
Placebo Compound treatment
1
Glutamine Compound treatment
1
SKMEL5 Cell line
1
Tumor Organism part
1
MCF7 Cell line
1
Lymph node Organism part
1
Tonsil Organism part
1
Benign nevi Disease state
1
Fetal bovine serum in media Growth condition
1
Bacterial endotoxin Compound treatment
1
Control Compound treatment
1
Lymphatic endothelial cell Cell type
1
T3aNxM1 Disease staging
1
Hypericin incubated, not irrad... Growth condition
1
Hypericin incubated, irradiate... Growth condition
1
Actinomycin D Compound treatment
1
Johnsen score count 3.2: Serto... Histology
1
BT474 Cell line
1
Pretreatment primary sample Clinical info
1
Vascular smooth muscle cell Cell type
1
Chondrocyte Cell type
1
ERalpha transfected Genotype
1
ERbeta transfected Genotype
1
T4aN0M0 Disease staging
1
Multiple myeloma Disease state
1
HPL1 Cell line
1
Wilms' tumor Disease state
1
Duchenne muscular dystrophy Disease state
1
Spermatid Cell type
1
Testis Organism part
1
Native skin Cell type
1
Johnsen score count 2: Sertoli... Histology
1
ITS medium with albumin-bound ... Growth condition
1
ITS medium Growth condition
1
Postprandial lipid micelles in... Growth condition
1
Experimental malaria-infected Disease state
1
Inter-prandial lipid micelles ... Growth condition
1
Spermatocyte Cell type
1
Superior cervical ganglion Organism part
1
Respiratory syncytial virus Infection
1
Cartilage Organism part
1
Seminiferous tubule Organism part
1
Cancer1 Replicate
1
Methotrexate Compound treatment
1
Enzo Labeling Protocol type
1
Whole blood Organism part
1
Plasma cell Cell type
1
B lymphocyte Cell type
1
Porphyromonas gingivalis Infection
1
MCF-7 Cell line
1
Superficial transitional cell ... Disease state
1
Oligodendroglioma Disease state
1
Met5A Cell line
1
T47-D Cell line
1
M1 macrophage Cell type
1
Astrocyte Cell type
1
Frontal cortex, primary motor ... Organism part
1
Interferon-gamma + lipopolysac... Compound treatment
1
Aggregatibacter actinomycetemc... Infection
1
Lipopolysaccharide Compound treatment
1
Cigarette smoke Growth condition
1
Incubator control Growth condition
1
Glucocorticoid sensitive Phenotype
1
Keratinocyte Cell type
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
TaN0M0 Disease staging
1
Idiopathic dilated cardiomyopa... Disease state
1
U87 Cell line
1
U373 Cell line
1
Relapse 1; ER status ER+; brai... Clinical info
1
Spleen Organism part
1
None Gene modification
1
Carcinoma in situ lesion Disease state
1
Lung Organism part
1
SKBR3 Cell line
1
GLI60 Cell line
1
Sporadic basal-like breast can... Disease state
1
Baseline uninfected Disease state
1
Serum starvation synchronizati... Growth condition
1
Sapphyrin PCI-2053 Compound treatment
1
Atrioventricular node Organism part
1
Mannitol Compound treatment
1
5-aza-2'-deoxycytidine + trich... Compound treatment
1
Prostate Organism part
1
Acute malaria, natural infecti... Disease state
1
Affymetrix Labeling Protocol type
1
HMEC184 Cell line
1
M-CSF Compound treatment
1
Trichostatin A Compound treatment
1
Duodenum Organism part
1
MCF10A Cell line
1
Entorhinal cortex Organism part
1
CD4+ T cell Cell type
1
CD8+ T cell Cell type
1
Treated malaria, natural infec... Disease state
1
Training set Population
1
Test set Population
1
R-(-)-apomorphine HCl Compound treatment
1
Geriatric Developmental stage
1
Pediatric Developmental stage
1
Mature monocyte derived dendri... Cell type
1
Tongue Organism part
1
KSHV infection Disease state
1
Superficial transitional cell ... Disease state
1
Endometrioid carcinoma Disease state
1
Cigarette smoke Compound treatment
1
HMT3522S1 Cell line
1
Primary gastric tumor Organism part
1
Muscle invasive carcinoma Disease state
1
Layer 2 stellate neuron Cell type
1
Layer 3 neuron Cell type
1
Smooth muscle Organism part
1
Blood Organism part
1
Bone marrow Organism part
1
Invasive breast cancer Disease state
1
HTERT/HPVE6/HPVE7/SV40t/hRas t... Gene modification
1
Bis [(+)-tartrato] diantimonat... Compound treatment
1
CD133+ G0 phase Phenotype
1
CD133+ G1 phase Phenotype
1
Control RNAi
1
SIM2s RNAi
1
Glucocorticoid resistant Phenotype
1
RM 82 Cell line
1
Plasma cell leukemia Disease state
1
Monoclonal gammopathy of undet... Disease state
1
Chronic lymphocytic leukemia Disease state
1
Granulocyte-colony stimulating... Compound treatment
1
Macaca mulatta Organism
1
KSHV-negative EBV-positive Clinical info
1
Epidermal growth factor Compound treatment
1
Endothelial cell + pericyte Cell type
1
Sapphyrin PCI-2055 Compound treatment
1
Chronic myelogenous leukemia Disease state
1
A549 Cell line
1
Dimethyl sulfoxide Compound treatment
1
2-(3,4,5-trimethoxy-phenylamin... Compound treatment
1
N/a Test result
1
Non-basal-like breast cancer Disease state
1
Trigeminal ganglion Organism part
1
Vasectomized Clinical history
1
Basal cell Cell type
1
X-linked chronic granulomatous Disease state
1
HTERT transduced Gene modification
1
Epilepsy Disease state
1
Psoriatic lesional biopsy Clinical info
1
Uninvolved biopsy Clinical info
1
Female Sex
1
Male Sex
1
Beas2B Cell line
1
Unsynchronized Growth condition
1
Poorly differentiated gastric ... Disease state
1
Capra hircus Organism
1
Granulocyte macrophage-colony ... Compound treatment
1
Huntington's disease Disease state
1
Immediately after exercise Clinical info
1
Fu97 Cell line
1
Invasive ductal carcinoma Histology
1
Pseudomonas aeruginosa Infection
1
Rapamycin Compound treatment
1
Phorbol 12-myristate 13-acetat... Compound treatment
1
Relapse 0; ER status ER+; brai... Clinical info
1
Skin Organism part
1
MiR15a/miR16-1 transfection Gene modification
1
WGWWCW polyamide and dihydrote... Compound treatment
1
SM1 Cell line
1
Stage II Disease staging
1
T3bN1M0 Disease staging
1
Carboplatin resistant Test result
1
Carboplatin sensitive Test result
1
Grade II Tumor grading
1
SNU1 Cell line
1
Normal1 Replicate
1
Chloroguine Compound treatment
1
Valproic acid Compound treatment
1
Daudi Burkitt's lymphoma Disease state
1
Trachea Organism part
1
Estrogen receptor 1 positive; ... Test result
1
Uninfected control RNAi
1
Mononuclear cell Cell type
1
Monocyte at intermediate diffe... Cell type
1
PT3 Disease staging
1
Measles virus Chicago-1 strain Infection
1
Kaposi's sarcoma-associated he... Infection
1
Nickel(II) chloride hexahydrat... Compound treatment
1
Primary blood vessel endotheli... Cell type
1
4OH-tamoxifen Compound treatment
1
Leydig cell Cell type
1
Infectious colitis Disease state
1
Empty vector Gene modification
1
Expression Profiles
E-GEOD-5258: Transcription profiling of human cell lines freely cycling treated with 164 distinct small molecules - Broad Connectivity Map CMAP Set 1
Experimental Factors
Show expression profile  /  experiment details

 
E-AFMX-5: Transcription profiling of human cell lines and tissues (GNF/Novartis)
Experimental Factors
Cell type Organism part Disease state
Show expression profile  /  experiment details

 
E-MEXP-2034: Transcription profiling of human primary prostate epithelial and stromal cells exposed to 4-methylsulphinylbutyl and 3-methylsulphinypropyl isothiocyanates
Experimental Factors
Show expression profile  /  experiment details

 
E-MEXP-440: Transcription profiling of lapatinib treated of breast cancer cell lines
Experimental Factors
Show expression profile  /  experiment details

 
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