GATA1
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Homo sapiens |
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GATA1 is differentially expressed in 173 experiments: 49 organism parts: bone marrow, liver, ... (47 more);, 118 disease states: normal, chronic myelogenous leukemia, ... (116 more);, 58 cell types 98 cell lines 20 compound treatments and 61 other conditions. |
| Synonyms |
GF1, NFE1, GATA-1, ERYF1 |
| Orthologs |
Gata1
(Rattus norvegicus)
Q4H3F5_CIOIN
(Ciona intestinalis)
GATA1
(Bos taurus)
DAL80
(Saccharomyces cerevisiae)
gata1a
(Danio rerio)
Gata1
(Mus musculus)
GAT1
(Saccharomyces cerevisiae)
GZF3
(Saccharomyces cerevisiae)
GLN3
(Saccharomyces cerevisiae)
grn
(Drosophila melanogaster)
gata1b
(Danio rerio)
gata1
(Xenopus laevis)
GATA1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0003682, GO:0003677, GO:0008285, GO:0008270, GO:0008301, GO:0003700, GO:0007267, GO:0008584, GO:0031965, GO:0007596, GO:0005515, GO:0005730, GO:0005634, GO:0005654, GO:0005667, GO:0043066, GO:0000122, GO:0046872, GO:0006355, GO:0006366, GO:0045944, GO:0043565, GO:0017053, GO:0035162, GO:0010559, GO:0060009, GO:0048821, GO:0030502, GO:0048468, GO:0002039, GO:0050731, GO:0070742, GO:0045768, GO:0001701, GO:0070527, GO:0033690, GO:0071372, GO:0030099, GO:0071320, GO:0030220, GO:0030222, GO:0030218, GO:0030219, GO:2000678, GO:0000981, GO:0000976, GO:0000977, GO:0000978, GO:0001158, GO:0030221, GO:0097028, GO:0001078, GO:0001077, GO:0001085, GO:0010724, GO:0035854, GO:0071733 |
| Gene Ontology Term |
transcriptional repressor complex, DNA binding, protein binding, regulation of transcription, DNA-dependent, negative regulation of cell proliferation, negative regulation of apoptosis, metal ion binding, male gonad development, DNA bending activity, cell-cell signaling, blood coagulation, transcription from RNA polymerase II promoter, sequence-specific DNA binding, positive regulation of transcription from RNA polymerase II promoter, nucleus, transcription factor complex, chromatin binding, nucleoplasm, negative regulation of transcription from RNA polymerase II promoter, embryonic hemopoiesis, nucleolus, nuclear membrane, zinc ion binding, platelet aggregation, cellular response to cAMP, erythrocyte development, in utero embryonic development, positive regulation of peptidyl-tyrosine phosphorylation, cellular response to follicle-stimulating hormone stimulus, C2H2 zinc finger domain binding, erythrocyte differentiation, platelet formation, positive regulation of anti-apoptosis, regulation of glycoprotein biosynthetic process, megakaryocyte differentiation, positive regulation of osteoblast proliferation, p53 binding, negative regulation of bone mineralization, myeloid cell differentiation, cell development, Sertoli cell development, eosinophil differentiation, sequence-specific DNA binding transcription factor activity, transcription regulatory region sequence-specific DNA binding, sequence-specific DNA binding RNA polymerase II transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific DNA binding, basophil differentiation, RNA polymerase II transcription factor binding, enhancer sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, RNA polymerase II regulatory region sequence-specific DNA binding, dendritic cell differentiation, negative regulation of transcription regulatory region DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcriptional activation by promoter-enhancer looping, eosinophil fate commitment, regulation of definitive erythrocyte differentiation |
| Ensembl Family Description |
TRANSCRIPTION FACTOR GATA GATA BINDING |
| InterPro ID |
IPR016374, IPR000679 |
| InterPro Term |
TF_GATA-1/2/3, Znf_GATA |
| Ensembl Family |
ENSFM00500000269911 |
| Ensembl Protein ID |
ENSP00000365858, ENSP00000365853, ENSP00000404985 |
| HGNC Symbol |
GATA1 |
| EMBL-Bank ID |
M30601, X17254, BC009797, CH471224, AF196971 |
| Gene-Disease Assocation |
DYSERYTHROPOIETIC ANEMIA WITH THROMBOCYTOPENIA, DOWN SYNDROME, THROMBOCYTOPENIA, PLATELET DYSFUNCTION, HEMOLYSIS, AND IMBALANCED, ANEMIA, X-LINKED, WITHOUT THROMBOCYTOPENIA |
| Entrez Gene ID |
2623 |
| UniGene ID |
Hs.765 |
| UniProt Accession |
P15976, C9JJR4, B7WNQ9 |
| Ensembl Gene ID |
ENSG00000102145 |
| RefSeq ID |
NP_002040, NM_002049 |
| Description |
GATA binding protein 1 (globin transcription factor 1) [Source:HGNC Symbol;Acc:4170] |
| Ensembl Transcript ID |
ENST00000447551, ENST00000376665, ENST00000376670 |
| Design Element |
36787_at, ENST00000376670, ENST00000447551, X17254_at, 210446_3p_at, ENST00000376665, Hs2.765.2.S1_3p_s_at, Hs2.765.2.S1_3p_at, g183071_3p_at, 210446_at, 1555590_a_at, g183071_3p_x_at, 1555590_3p_a_at |
| Search EB-eye |
ENSG00000102145
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