E2F1
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Homo sapiens |
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E2F1 is differentially expressed in 285 experiments: 100 organism parts: bone marrow, kidney, ... (98 more);, 181 disease states: normal, acute lymphoblastic leukemia, ... (179 more);, 84 cell types 337 cell lines 41 compound treatments and 70 other conditions. |
| Synonyms |
RBBP3, RBP3 |
| Orthologs |
E2f1
(Mus musculus)
E2f1
(Rattus norvegicus)
E2F1_CHICK
(Gallus gallus)
E1BG94_BOVIN
(Bos taurus)
E2F1
(Danio rerio)
E2f
(Drosophila melanogaster)
e2f1
(Xenopus laevis)
E2F1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0003677, GO:0010628, GO:0008283, GO:0003714, GO:0003700, GO:0007283, GO:0004693, GO:0000080, GO:0000082, GO:0005515, GO:0006915, GO:0005737, GO:0005739, GO:0005634, GO:0005654, GO:0005667, GO:0000122, GO:0051726, GO:0006355, GO:0006351, GO:0000278, GO:0045944, GO:0043565, GO:0045892, GO:0045893, GO:0035189, GO:0000085, GO:0048255, GO:0030900, GO:0048146, GO:0071456, GO:0071398, GO:0071930, GO:2000045 |
| Gene Ontology Term |
cyclin-dependent protein kinase activity, DNA binding, negative regulation of transcription, DNA-dependent, protein binding, apoptosis, regulation of transcription, DNA-dependent, cytoplasm, cell proliferation, transcription, DNA-dependent, positive regulation of gene expression, mitotic cell cycle, transcription corepressor activity, spermatogenesis, G1 phase of mitotic cell cycle, transcription factor binding, sequence-specific DNA binding, positive regulation of transcription from RNA polymerase II promoter, regulation of cell cycle, G1/S transition of mitotic cell cycle, nucleus, Rb-E2F complex, transcription factor complex, nucleoplasm, negative regulation of transcription from RNA polymerase II promoter, positive regulation of transcription, DNA-dependent, mitochondrion, mRNA stabilization, cellular response to hypoxia, forebrain development, cellular response to fatty acid, positive regulation of fibroblast proliferation, G2 phase of mitotic cell cycle, sequence-specific DNA binding transcription factor activity, regulation of G1/S transition of mitotic cell cycle, negative regulation of transcription involved in G1/S phase of mitotic cell cycle |
| InterPro ID |
IPR003316 |
| InterPro Term |
E2F_TDP |
| Ensembl Family Description |
TRANSCRIPTION FACTOR E2F |
| Ensembl Family |
ENSFM00500000270064 |
| Description |
E2F transcription factor 1 [Source:HGNC Symbol;Acc:3113] |
| RefSeq ID |
NM_005225, NP_005216 |
| EMBL-Bank ID |
AF516106, M96577, BC058902, U47676, U47677, U47675, S49592, BC050369, AL121906, S74230 |
| UniGene ID |
Hs.654393 |
| HGNC Symbol |
E2F1 |
| Entrez Gene ID |
1869 |
| UniProt Accession |
Q01094 |
| Ensembl Protein ID |
ENSP00000345571 |
| Ensembl Gene ID |
ENSG00000101412 |
| Ensembl Transcript ID |
ENST00000343380 |
| Design Element |
ENST00000343380, 204947_at, 2028_s_at, U47677_at, g12669910_3p_s_at, 1322_at, S49592_s_at |
| Search EB-eye |
ENSG00000101412
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