STK4
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Homo sapiens |
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STK4 is differentially expressed in 290 experiments: 106 organism parts: bone marrow, lung, ... (104 more);, 235 disease states: normal, breast carcinoma, ... (233 more);, 108 cell types 366 cell lines 39 compound treatments and 82 other conditions. |
| Synonyms |
KRS2, MST1, YSK3 |
| Orthologs |
ENSCING00000009234
(Ciona intestinalis)
Stk4
(Mus musculus)
STK4
(Gallus gallus)
KIC1
(Saccharomyces cerevisiae)
Stk4
(Rattus norvegicus)
STK4_BOVIN
(Bos taurus)
hpo
(Drosophila melanogaster)
stk4
(Xenopus laevis)
STK4
(Canis familiaris)
(Compare orthologs)
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| InterPro Term |
SARAH, Prot_kinase_cat_dom, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom, SARAH_domain |
| InterPro ID |
IPR002290, IPR011524, IPR001245, IPR017442, IPR000719, IPR020635, IPR024205 |
| Gene Ontology ID |
GO:0008134, GO:0008285, GO:0007165, GO:0007243, GO:0007417, GO:0016772, GO:0004713, GO:0042803, GO:0042802, GO:0005524, GO:0005515, GO:0006917, GO:0005737, GO:0005634, GO:0004672, GO:0004674, GO:0043065, GO:0006468, GO:0000902, GO:0000166, GO:0018105, GO:0046777, GO:0000287, GO:0046983, GO:0046621, GO:0090090, GO:0001841, GO:0001569, GO:0043539, GO:0035329, GO:0060706, GO:0030216, GO:0003157, GO:0060215, GO:0071902 |
| Gene Ontology Term |
protein binding, cytoplasm, negative regulation of cell proliferation, peptidyl-serine phosphorylation, protein tyrosine kinase activity, cell morphogenesis, positive regulation of apoptosis, negative regulation of organ growth, transcription factor binding, identical protein binding, ATP binding, induction of apoptosis, magnesium ion binding, protein dimerization activity, transferase activity, transferring phosphorus-containing groups, nucleus, nucleotide binding, protein serine/threonine kinase activity, protein homodimerization activity, signal transduction, protein kinase activity, central nervous system development, intracellular protein kinase cascade, neural tube formation, keratinocyte differentiation, cell differentiation involved in embryonic placenta development, patterning of blood vessels, hippo signaling cascade, negative regulation of canonical Wnt receptor signaling pathway, protein serine/threonine kinase activator activity, primitive hemopoiesis, protein autophosphorylation, endocardium development, protein phosphorylation, positive regulation of protein serine/threonine kinase activity |
| Ensembl Family |
ENSFM00510000502760 |
| Ensembl Family Description |
SERINE/THREONINE KINASE EC_2.7.11.1 |
| RefSeq ID |
NP_006273, NM_006282 |
| UniProt Accession |
Q13043, Q9BS84, F5H5B4 |
| Ensembl Protein ID |
ENSP00000361887, ENSP00000361892, ENSP00000379957, ENSP00000443514 |
| UniGene ID |
Hs.472838, Hs.700137 |
| EMBL-Bank ID |
BC058916, Z93016, U60207, AK315238, BC093768, CH471077, AL109839, BC029511, BC005231, U18297 |
| Entrez Gene ID |
6789 |
| HGNC Symbol |
STK4 |
| Description |
serine/threonine kinase 4 [Source:HGNC Symbol;Acc:11408] |
| Ensembl Gene ID |
ENSG00000101109 |
| Ensembl Transcript ID |
ENST00000480745, ENST00000487587, ENST00000488618, ENST00000372806, ENST00000372801, ENST00000499879, ENST00000396731, ENST00000474717 |
| Design Element |
225364_at, ENST00000474717, 1569791_at, 223746_at, Hs.268051.0.A1_3p_at, ENST00000372806, g13528860_3p_at, U18297_s_at, ENST00000372801, 59574_at, 205411_at, ENST00000499879, ENST00000396731, 211085_s_at, g5454095_3p_at, ENST00000480745, 53858_at, 36294_at, 236259_at, 59278_at, Hs.250824.0.S1_3p_at, g405738_3p_s_at, ENST00000488618, 77474_at, ENST00000487587, Hs2.407629.1.S1_3p_at |
| Search EB-eye |
ENSG00000101109
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