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MMP9
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Homo sapiens
MMP9 is differentially expressed in 240 experiments: 111 organism parts: bone marrow, thymus, ... (109 more);, 137 disease states: normal, acute myeloid leukemia, ... (135 more);, 87 cell types 185 cell lines 30 compound treatments and 61 other conditions.
Synonyms CLG4B
Orthologs Q9TVA6_BOVIN (Bos taurus)   Mmp9 (Mus musculus)   MMP9 (Gallus gallus)   mmp9 (Danio rerio)   Mmp9 (Rattus norvegicus)   ENSXETG00000033145 (Xenopus laevis)   mmp9 (Xenopus laevis)   MMP9_CANFA (Canis familiaris)   (Compare orthologs)
Gene Ontology Term response to oxidative stress, protein binding, metalloendopeptidase activity, extracellular space, protein complex, metallopeptidase activity, peptidase activity, proteinaceous extracellular matrix, metabolic process, metal ion binding, extracellular region, response to hypoxia, positive regulation of apoptosis, cell growth, response to nutrient, response to lipopolysaccharide, response to drug, proteolysis, extracellular matrix organization, extracellular matrix, response to ethanol, response to heat, response to radiation, response to mechanical stimulus, zinc ion binding, response to vitamin A, response to nicotine, response to tumor necrosis factor, collagen catabolic process, ossification, cellular response to cell-matrix adhesion, response to retinoic acid, tissue remodeling, anatomical structure regression, skeletal system development, response to estradiol stimulus, positive regulation of keratinocyte migration, collagen binding, response to organic substance, protein complex binding, positive regulation of angiogenesis, macrophage differentiation, response to hyperoxia, transformation of host cell by virus, positive regulation of synaptic plasticity, cellular response to interleukin-1, fibronectin binding, cellular response to cytokine stimulus, response to organic cyclic compound, cellular response to low-density lipoprotein particle stimulus
InterPro Term Hemopexin/matrixin_repeat, Pept_M10_metallopeptidase, Peptidase_Metallo, PT, Peptidoglycan-bd-like, FN_type2_col-bd, Pept_M10A_matrixin
UniProt Accession Q9Y354, P14780, F5H3W7
Gene-Disease Assocation INTERVERTEBRAL DISC DISEASE; IDD, METAPHYSEAL ANADYSPLASIA 2; MANDP2
Search EB-eye ENSG00000100985
Show more properties
Experimental Factors
Organism part

studied in E-GEOD-803, E-GEOD-6573, E-GEOD-1577, E-MEXP-433, E-GEOD-3526, ... (25 experiments)

3
1
Number of published studies where the gene is over/under expressed compared to the gene's overall mean expression level in the study.

anatomogram

Cell line

studied in E-GEOD-5258, E-GEOD-19639, E-GEOD-18005, E-GEOD-2450, E-MTAB-62, ... (27 experiments)

Factor Value U/D Experiments
MCF-7
3
E-GEOD-20081, E-GEOD-19639, E-GEOD-3529
primary culture
2
E-GEOD-2450, E-GEOD-1657
MC116
1
E-MTAB-37
UACC893
1
E-MTAB-37
GM10832
1
E-TABM-321
H1648
1
E-MTAB-62
179 more value(s).


Cell type

studied in E-GEOD-360, E-GEOD-13909, E-GEOD-20677, E-GEOD-13987, E-GEOD-21750, ... (44 experiments)

Factor Value U/D Experiments
2
E-TABM-145, E-TABM-130
CD8+ T cell
1
2
E-GEOD-6740, E-MTAB-25, E-AFMX-5
plasma cell
1
E-MEXP-2360
hematopoietic stem cell
1
E-MEXP-1403
naive
1
E-GEOD-2649
NK cell
1
E-GEOD-3982
81 more value(s).


Disease state

studied in E-GEOD-3307, E-GEOD-1577, E-TABM-15, E-GEOD-16363, E-MTAB-62, ... (55 experiments)

Factor Value U/D Experiments
AIDS-KS, HIV+, nodular (late) stage
2
E-MEXP-66, E-MTAB-62
adrenocortical carcinoma
2
E-TABM-311, E-GEOD-10927
control
2
E-GEOD-8121, E-GEOD-16728
severe acute respiratory syndrome
1
E-GEOD-1739
sickle cell anaemia
1
E-GEOD-16728
Calpain 3 mutation
1
E-GEOD-3307
131 more value(s).


Compound treatment

studied in E-GEOD-7400, E-GEOD-15205, E-TABM-782, E-GEOD-5099, E-GEOD-15811, ... (22 experiments)

Factor Value U/D Experiments
none
4
5
E-MEXP-1958, E-MEXP-1601, E-TABM-782, E-GEOD-7400, E-GEOD-4600, ... (9 experiments)
BCR/ABL1
1
E-GEOD-15811
sevoflurane
1
E-GEOD-4386
ZMYM2/FGFR1
1
E-GEOD-15811
PGE2
1
E-MEXP-1230
estradiol
1
E-GEOD-20081
24 more value(s).


Biopsy tissue

studied in E-GEOD-5851

Factor Value U/D Experiments
rib
1
E-GEOD-5851
liver
1
E-GEOD-5851


BioSourceProvider
studied in E-GEOD-19519, E-GEOD-19480

Blood/non-blood meta-groups
studied in E-MTAB-62

Cancer site
studied in E-GEOD-4271

Cell treatment
studied in E-MEXP-1192

Clinical history
studied in E-GEOD-19743, E-GEOD-7967, E-GEOD-21374, E-GEOD-21589, E-GEOD-16363 ... (5 experiments)

Clinical info
studied in E-GEOD-19743, E-MTAB-37, E-GEOD-6710, E-MEXP-1251, E-GEOD-2191, ... (8 experiments)

Clinical treatment
studied in E-GEOD-6532

coriell cell line repository identifier
studied in E-GEOD-19519

Developmental stage
studied in E-GEOD-20033, E-GEOD-3140, E-MEXP-2359, E-MTAB-62

Disease staging
studied in E-GEOD-89, E-GEOD-19743, E-TABM-147, E-GEOD-21138

Environmental stress
studied in E-GEOD-1518

Estrogen receptor status
studied in E-GEOD-6532

family id
studied in E-GEOD-19519

Genetic modification
studied in E-GEOD-7011, E-MTAB-73, E-GEOD-7578

Genotype
studied in E-TABM-1029, E-GEOD-3494, E-GEOD-17476, E-GEOD-21750, E-GEOD-2292, ... (11 experiments)

Gestation age
studied in E-GEOD-14334

369 groups
studied in E-MTAB-62

4 groups from blood to incompletely diff
studied in E-MTAB-62

96 groups
studied in E-MTAB-62

Growth condition
studied in E-TABM-263, E-GEOD-5681, E-GEOD-12773, E-MEXP-1446, E-GEOD-22278, ... (9 experiments)

Her2 fish
studied in E-GEOD-20194, E-GEOD-16716

Histology
studied in E-TABM-234, E-TABM-276

Individual
studied in E-MTAB-197, E-TABM-325, E-GEOD-1926, E-TABM-666, E-GEOD-19330, ... (23 experiments)

Infection
studied in E-GEOD-2405, E-GEOD-12108, E-MEXP-561

Injury
studied in E-GEOD-19743

Karyotype
studied in E-GEOD-22056

Ki67 ihc
studied in E-GEOD-21653

Material type
studied in E-MEXP-455, E-GEOD-9171

15 meta groups
studied in E-MTAB-62

4 meta groups
studied in E-MTAB-62

6 meta groups
studied in E-MTAB-62

Molecular subtype
studied in E-GEOD-21653

Observation
studied in E-TABM-276

organ
studied in E-GEOD-24283

Organism
studied in E-GEOD-7540, E-GEOD-1801, E-AFMX-1

Organism status
studied in E-GEOD-19188

Original diagnosis
studied in E-GEOD-21521

Performer
studied in E-LGCL-5

Phenotype
studied in E-GEOD-1493, E-GEOD-21750, E-GEOD-1657, E-GEOD-4600, E-MEXP-1403 ... (5 experiments)

Population
studied in E-GEOD-4342

Progesterone receptor status
studied in E-GEOD-3494, E-GEOD-6532

Protocol type
studied in E-GEOD-3254, E-GEOD-21837, E-GEOD-19445, E-GEOD-19246

Replicate
studied in E-GEOD-10896

RNAi
studied in E-MEXP-101, E-GEOD-3697, E-MEXP-1857

Sample preparation
studied in E-GEOD-16728

sampleID
studied in E-GEOD-24283

Sampling time point
studied in E-GEOD-16797, E-GEOD-19743

sbr grade
studied in E-GEOD-21653

Sex
studied in E-GEOD-19743, E-GEOD-19069, E-GEOD-2466, E-GEOD-22541, E-GEOD-7307 ... (5 experiments)

Stimulation
studied in E-GEOD-11428

stimulus
studied in E-GEOD-22103

Strain or line
studied in E-TABM-125

Subtype
studied in E-GEOD-24283

Survival time
studied in E-GEOD-19188

Test result
studied in E-TABM-276

Treatment
studied in E-GEOD-19246

Treatments comments
studied in E-GEOD-20194, E-GEOD-16716

Ttf
studied in E-GEOD-21521

Tumor grading
studied in E-GEOD-4290, E-GEOD-4271, E-GEOD-3494, E-GEOD-4922

Vehicle
studied in E-GEOD-5258

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Gene Expression Atlas 2.0.11.1- 12/23/11 3:09:34 PM