EP300
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Homo sapiens |
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EP300 is differentially expressed in 271 experiments: 112 organism parts: ovary, placenta, ... (110 more);, 179 disease states: normal, acute myeloid leukemia, ... (177 more);, 90 cell types 409 cell lines 39 compound treatments and 71 other conditions. |
| Synonyms |
p300, KAT3B |
| Orthologs |
EP300
(Gallus gallus)
ENSCING00000009030
(Ciona intestinalis)
F1LPY5_RAT
(Rattus norvegicus)
ENSCING00000017171
(Ciona intestinalis)
Ep300
(Mus musculus)
EP300
(Bos taurus)
ep300a
(Danio rerio)
ep300b
(Danio rerio)
BDF1
(Saccharomyces cerevisiae)
BDF2
(Saccharomyces cerevisiae)
Q28E87_XENTR
(Xenopus laevis)
EP300
(Canis familiaris)
nej
(Drosophila melanogaster)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008134, GO:0009887, GO:0003677, GO:0010628, GO:0008270, GO:0003713, GO:0003712, GO:0003700, GO:0008013, GO:0007049, GO:0016573, GO:0016407, GO:0007399, GO:0004402, GO:0007507, GO:0007519, GO:0042493, GO:0048565, GO:0065004, GO:0016746, GO:0042542, GO:0042771, GO:0005515, GO:0004468, GO:0006915, GO:0005737, GO:0005634, GO:0005654, GO:0005667, GO:0005813, GO:0019901, GO:0001934, GO:0050714, GO:0000785, GO:0045727, GO:0000123, GO:0045793, GO:0046872, GO:0001756, GO:0006355, GO:0006351, GO:0045944, GO:0031490, GO:0045862, GO:0045893, GO:0043491, GO:0001666, GO:0033613, GO:0045471, GO:0030307, GO:0045087, GO:0010560, GO:0003823, GO:0060298, GO:0009749, GO:0060177, GO:0051384, GO:0051019, GO:0051059, GO:0051091, GO:0043967, GO:0043923, GO:0014070, GO:0043627, GO:0042975, GO:0032403, GO:0050681, GO:0031324, GO:0031325, GO:0032526, GO:0018393, GO:0045773, GO:0043388, GO:0032993, GO:0032967, GO:0018076, GO:0044419, GO:0001889, GO:0070542, GO:0051592, GO:0060765, GO:0030324, GO:0070301, GO:0033160, GO:0032025, GO:0032092, GO:0035259, GO:0000978, GO:0001102, GO:0001085 |
| Gene Ontology Term |
response to hydrogen peroxide, DNA binding, protein binding, apoptosis, positive regulation of translation, histone acetyltransferase activity, positive regulation of protein secretion, regulation of transcription, DNA-dependent, lysine N-acetyltransferase activity, cytoplasm, beta-catenin binding, acetyltransferase activity, innate immune response, transcription, DNA-dependent, positive regulation of gene expression, protein-DNA complex assembly, metal ion binding, response to hypoxia, somitogenesis, positive regulation of cell size, transcription factor binding, protein kinase B signaling cascade, cell cycle, histone acetyltransferase complex, positive regulation of transcription from RNA polymerase II promoter, centrosome, transcription coactivator activity, DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis, transcription cofactor activity, protein kinase binding, nucleus, heart development, histone acetylation, chromatin DNA binding, transcription factor complex, response to drug, nervous system development, positive regulation of cell growth, chromatin, nucleoplasm, response to ethanol, skeletal muscle tissue development, positive regulation of transcription, DNA-dependent, organ morphogenesis, digestive tract development, positive regulation of proteolysis, zinc ion binding, transferase activity, transferring acyl groups, glucocorticoid receptor binding, androgen receptor binding, antigen binding, regulation of androgen receptor signaling pathway, response to calcium ion, positive regulation of collagen biosynthetic process, peroxisome proliferator activated receptor binding, positive regulation of protein import into nucleus, translocation, N-terminal peptidyl-lysine acetylation, positive regulation by host of viral transcription, regulation of angiotensin metabolic process, positive regulation of DNA binding, response to cobalt ion, response to estrogen stimulus, protein-DNA complex, response to fatty acid, positive regulation of axon extension, positive regulation of glycoprotein biosynthetic process, response to retinoic acid, negative regulation of cellular metabolic process, positive regulation of cellular metabolic process, interspecies interaction between organisms, NF-kappaB binding, cellular response to hydrogen peroxide, lung development, internal peptidyl-lysine acetylation, liver development, response to glucose stimulus, protein complex binding, positive regulation of protein binding, response to glucocorticoid stimulus, mitogen-activated protein kinase binding, positive regulation of sarcomere organization, histone H4 acetylation, sequence-specific DNA binding transcription factor activity, activating transcription factor binding, positive regulation of protein phosphorylation, RNA polymerase II core promoter proximal region sequence-specific DNA binding, response to organic cyclic compound, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription factor binding, positive regulation of sequence-specific DNA binding transcription factor activity |
| InterPro ID |
IPR000197, IPR001487, IPR010303, IPR000433, IPR003101, IPR014744, IPR013178 |
| InterPro Term |
DUF902_CREBbp, Znf_TAZ, Bromodomain, Znf_ZZ, KIX, Nuc_rcpt_coact_CREBbp, Histone_H3-K56_AcTrfase_RTT109 |
| Ensembl Family |
ENSFM00250000000805 |
| Entrez Gene ID |
2033 |
| HGNC Symbol |
EP300 |
| RefSeq ID |
NR_031694, NP_001420, NM_001429 |
| EMBL-Bank ID |
U01877, AL035658, EU790779, AL096765, CH471095, AL080243 |
| UniProt Accession |
Q09472, B5A250 |
| Ensembl Gene ID |
ENSG00000100393 |
| Ensembl Protein ID |
ENSP00000263253 |
| Description |
E1A binding protein p300 [Source:HGNC Symbol;Acc:3373] |
| UniGene ID |
Hs.655211, Hs.517517 |
| Ensembl Family Description |
EC_2.3.1.48 |
| Gene-Disease Assocation |
COLORECTAL CANCER; CRC, RUBINSTEIN-TAYBI SYNDROME 2; RSTS2, RUBINSTEIN-TAYBI SYNDROME 1; RSTS1 |
| Ensembl Transcript ID |
ENST00000263253 |
| Design Element |
Hs.25272.1.A1_3p_a_at, gnf1h06647_s_at, 33896_at, 202221_s_at, U01877_at, 213579_s_at, 551_at, ENST00000263253, Hs.25272.0.A2_3p_a_at |
| Search EB-eye |
ENSG00000100393
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