NLRC4
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Homo sapiens |
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NLRC4 is differentially expressed in 99 experiments: 15 organism parts: lung, bone marrow, ... (13 more);, 40 disease states: normal, adrenocortical carcinoma, ... (38 more);, 31 cell types 15 cell lines 15 compound treatments and 34 other conditions. |
| Synonyms |
CARD12, ipaf, CLAN1, CLANA, CLANB, CLANC, CLAND, CLAN, CLR2.1 |
| Orthologs |
NLRC4
(Bos taurus)
Nlrc4
(Mus musculus)
D3ZA97_RAT
(Rattus norvegicus)
nlrc4
(Xenopus laevis)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, protein binding, cytoplasm, intracellular, innate immune response, activation of caspase activity, positive regulation of apoptosis, ATP binding, magnesium ion binding, defense response to bacterium, nucleotide binding, protein homodimerization activity, regulation of apoptosis, detection of bacterium, activation of innate immune response, interleukin-1 beta secretion, inflammatory response, regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| InterPro Term |
NACHT_NTPase, CARD |
| Gene Ontology ID |
GO:0042803, GO:0005622, GO:0005524, GO:0005515, GO:0042742, GO:0006919, GO:0005737, GO:0005829, GO:0042981, GO:0043065, GO:0000166, GO:0000287, GO:0045087, GO:0016045, GO:0006954, GO:0002218, GO:0050702, GO:0043281 |
| InterPro ID |
IPR007111, IPR001315 |
| Ensembl Family |
ENSFM00250000009217 |
| Ensembl Family Description |
NLR FAMILY CARD DOMAIN CONTAINING 4 CARD LRR AND NACHT CONTAINING CLAN CASPASE RECRUITMENT DOMAIN CONTAINING 12 ICE PROTEASE ACTIVATING FACTOR IPAF |
| Ensembl Protein ID |
ENSP00000339666, ENSP00000385428, ENSP00000385090, ENSP00000354159 |
| HGNC Symbol |
NLRC4 |
| EMBL-Bank ID |
AY358152, AK314762, AL389934, CH471053, AY032589, AF376061, BC031555, AY027790, AY027787, AY027789, AY027788, AY035391 |
| UniProt Accession |
Q9NPP4 |
| Entrez Gene ID |
58484 |
| RefSeq ID |
NM_021209, NP_067032, NM_001199138, NM_001199139, NP_001186068, NP_001186067 |
| Description |
NLR family, CARD domain containing 4 [Source:HGNC Symbol;Acc:16412] |
| UniGene ID |
Hs.574741 |
| Ensembl Gene ID |
ENSG00000091106 |
| Ensembl Transcript ID |
ENST00000342905, ENST00000404025, ENST00000402280, ENST00000360906 |
| Design Element |
ENST00000360906, ENST00000404025, 1552553_a_at, ENST00000342905, ENST00000402280, Hs2.23248.1.S1_3p_a_at, 1552554_a_at, Hs2.23248.1.S2_3p_a_at |
| Search EB-eye |
ENSG00000091106
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