AURKA
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Homo sapiens |
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AURKA is differentially expressed in 350 experiments: 129 organism parts: bone marrow, blood, ... (127 more);, 237 disease states: normal, control, ... (235 more);, 114 cell types 335 cell lines 44 compound treatments and 78 other conditions. |
| Synonyms |
ARK1, STK15, BTAK, AurA, STK7, STK6 |
| Orthologs |
Aurka
(Mus musculus)
IPL1
(Saccharomyces cerevisiae)
AURKA
(Gallus gallus)
F7A0P0_CIOIN
(Ciona intestinalis)
Aurka
(Rattus norvegicus)
AURKA_BOVIN
(Bos taurus)
aurka
(Danio rerio)
aur
(Drosophila melanogaster)
ial
(Drosophila melanogaster)
aurka
(Xenopus laevis)
(Compare orthologs)
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| InterPro ID |
IPR002290, IPR001245, IPR017442, IPR000719, IPR020635 |
| Gene Ontology Term |
protein binding, mitotic cell cycle, protein tyrosine kinase activity, ATP binding, centrosome, spindle, nucleotide binding, kinase activity, protein serine/threonine kinase activity, protein kinase activity, ubiquitin protein ligase binding, response to estradiol stimulus, protein phosphorylation |
| Gene Ontology ID |
GO:0016301, GO:0004713, GO:0005524, GO:0005515, GO:0005819, GO:0005813, GO:0004672, GO:0004674, GO:0006468, GO:0000166, GO:0031625, GO:0000278, GO:0032355 |
| InterPro Term |
Prot_kinase_cat_dom, Ser/Thr_kinase_dom, Tyr_kinase_cat_dom, Ser-Thr/Tyr_kinase, Se/Thr_kinase-like_dom |
| Ensembl Family |
ENSFM00260000050511 |
| Ensembl Gene ID |
ENSG00000087586 |
| Ensembl Protein ID |
ENSP00000401358, ENSP00000388073, ENSP00000321591, ENSP00000405042, ENSP00000405170, ENSP00000216911, ENSP00000379243, ENSP00000379245, ENSP00000379247, ENSP00000379249, ENSP00000379250, ENSP00000379251, ENSP00000360407, ENSP00000393452 |
| HGNC Symbol |
AURKA |
| UniGene ID |
Hs.608070, Hs.250822 |
| RefSeq ID |
NM_003600, NP_003591, NP_940838, NP_940837, NP_940836, NP_940835, NP_940839, NM_198436, NM_198437, NM_198434, NM_198435, NM_198433 |
| Entrez Gene ID |
6790 |
| EMBL-Bank ID |
AL121914 |
| UniProt Accession |
Q5QPD4, Q5QPD1, Q5QPD2, A3KFJ0, A3KFJ2, A3KFJ1, O14965 |
| Description |
aurora kinase A [Source:HGNC Symbol;Acc:11393] |
| Ensembl Transcript ID |
ENST00000347343, ENST00000422322, ENST00000395909, ENST00000395907, ENST00000395915, ENST00000395914, ENST00000395913, ENST00000395911, ENST00000451915, ENST00000420474, ENST00000456249, ENST00000312783, ENST00000441357, ENST00000371356 |
| Gene-Disease Assocation |
COLORECTAL CANCER; CRC |
| Ensembl Family Description |
AURORA KINASE EC_2.7.11.1 AURORA/IPL1 RELATED KINASE ARK AURORA RELATED KINASE 1 SERINE/THREONINE KINASE SERINE/THREONINE KINASE AURORA |
| Design Element |
ENST00000312783, 84436_at, 208079_s_at, ENST00000347343, 34852_g_at, g4507274_3p_s_at, ENST00000422322, 204092_s_at, ENST00000395911, ENST00000395907, ENST00000441357, ENST00000395913, ENST00000395914, ENST00000395915, ENST00000456249, ENST00000371356, ENST00000451915, ENST00000420474, 34851_at, ENST00000395909 |
| Search EB-eye |
ENSG00000087586
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