BAX
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Homo sapiens |
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BAX is differentially expressed in 297 experiments: 119 organism parts: bone marrow, lung, ... (117 more);, 214 disease states: normal, acute myeloid leukemia, ... (212 more);, 86 cell types 318 cell lines 43 compound treatments and 71 other conditions. |
| Synonyms |
BCL2L4 |
| Orthologs |
BAX (2 of 2)
(Danio rerio)
baxa
(Danio rerio)
BAX_BOVIN
(Bos taurus)
ENSCING00000013537
(Ciona intestinalis)
Bax
(Mus musculus)
D4A9I1_RAT
(Rattus norvegicus)
Bax
(Rattus norvegicus)
bax
(Xenopus laevis)
NP_001003011.1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology Term |
cytosol, mitochondrial fusion, positive regulation of developmental pigmentation, endoplasmic reticulum, protein binding, apoptosis, response to wounding, cytoplasm, response to salt stress, cell proliferation, intracellular, negative regulation of cell proliferation, response to toxin, membrane, protein homooligomerization, lipid binding, spermatogenesis, activation of caspase activity, male gonad development, activation of caspase activity by cytochrome c, positive regulation of apoptosis, mitochondrial outer membrane, pore complex, soluble fraction, response to ionizing radiation, identical protein binding, sex differentiation, induction of apoptosis, germ cell programmed cell death, regulation of cell cycle, spermatid differentiation, nucleus, response to axon injury, protein heterodimerization activity, germ cell development, mitochondrial membrane, channel activity, post-embryonic development, nervous system development, protein homodimerization activity, DNA fragmentation involved in apoptotic nuclear change, response to DNA damage stimulus, response to gamma radiation, retinal cell programmed cell death, endoplasmic reticulum membrane, fertilization, neuron apoptosis, negative regulation of anti-apoptosis, cleavage of lamin, mitochondrion, regulation of apoptosis, negative regulation of neuron apoptosis, neuron migration, positive regulation of B cell apoptosis, B cell negative selection, myeloid cell homeostasis, regulation of mammary gland epithelial cell proliferation, activation of pro-apoptotic gene products, negative regulation of survival gene product expression, post-embryonic camera-type eye morphogenesis, negative regulation of fibroblast proliferation, blood vessel remodeling, negative regulation of protein binding, protein insertion into mitochondrial membrane involved in induction of apoptosis, positive regulation of release of sequestered calcium ion into cytosol, limb morphogenesis, establishment or maintenance of transmembrane electrochemical gradient, kidney development, B cell homeostatic proliferation, cerebral cortex development, regulation of neuron apoptosis, hypothalamus development, apoptotic mitochondrial changes, induction of apoptosis by intracellular signals, glycosphingolipid metabolic process, positive regulation of apoptosis involved in mammary gland involution, apoptosis in response to endoplasmic reticulum stress, B cell homeostasis, retina development in camera-type eye, ovarian follicle development, positive regulation of calcium ion transport into cytosol, BH3 domain binding, development of secondary sexual characteristics, regulation of protein heterodimerization activity, homeostasis of number of cells within a tissue, leukocyte homeostasis, release of cytochrome c from mitochondria, regulation of mitochondrial membrane potential, cellular response to UV, Sertoli cell proliferation, induction of apoptosis by extracellular signals, cytosolic part, regulation of protein homodimerization activity, response to acid, reduction of endoplasmic reticulum calcium ion concentration, negative regulation of peptidyl-serine phosphorylation, positive regulation of neuron apoptosis, induction of apoptosis in response to chemical stimulus, transformed cell apoptosis, odontogenesis of dentine-containing tooth, regulation of nitrogen utilization, vagina development, B cell apoptosis, regulation of mitochondrial membrane permeability, homeostasis of number of cells, release of matrix enzymes from mitochondria, nuclear fragmentation involved in apoptotic nuclear change, T cell homeostatic proliferation, mitochondrial permeability transition pore complex, mitochondrial fragmentation involved in apoptosis, induction of retinal programmed cell death, regulation of cysteine-type endopeptidase activity involved in apoptotic process, Bcl-2 family protein complex |
| Gene Ontology ID |
GO:0008289, GO:0008283, GO:0008285, GO:0016020, GO:0008053, GO:0010332, GO:0008635, GO:0010212, GO:0009566, GO:0009611, GO:0009651, GO:0009636, GO:0007283, GO:0007281, GO:0009791, GO:0007399, GO:0008584, GO:0051402, GO:0031966, GO:0007548, GO:0051260, GO:0048678, GO:0048515, GO:0042803, GO:0042802, GO:0005622, GO:0005625, GO:0005515, GO:0015267, GO:0006915, GO:0006922, GO:0006919, GO:0006917, GO:0005737, GO:0005739, GO:0005741, GO:0005634, GO:0005829, GO:0005789, GO:0005783, GO:0048087, GO:0006974, GO:0042981, GO:0043065, GO:0019987, GO:0006309, GO:0051726, GO:0001764, GO:0046930, GO:0046982, GO:0043524, GO:0046666, GO:0035234, GO:0010524, GO:0060041, GO:0060058, GO:0060068, GO:0060011, GO:0008629, GO:0008624, GO:0008634, GO:0008637, GO:0008633, GO:0010248, GO:0051434, GO:0048872, GO:0048873, GO:0051281, GO:0001101, GO:0042475, GO:0048597, GO:0002352, GO:0002358, GO:0006927, GO:0002262, GO:0048147, GO:0032471, GO:0006808, GO:0006687, GO:0001974, GO:0001776, GO:0001783, GO:0001782, GO:0044445, GO:0046902, GO:0051881, GO:0043281, GO:0001836, GO:0001822, GO:0001844, GO:0043525, GO:0043523, GO:0001541, GO:0043496, GO:0043497, GO:0031558, GO:0033599, GO:0021987, GO:0002904, GO:0045136, GO:0021854, GO:0033137, GO:0032091, GO:0035108, GO:0070059, GO:0034644, GO:0001777, GO:0032976, GO:0046674, GO:0030264, GO:0043653, GO:0005757, GO:0097136 |
| InterPro ID |
IPR002475, IPR000712 |
| InterPro Term |
Bcl2_BH, Bcl2-like_apoptosis |
| Ensembl Family Description |
APOPTOSIS REGULATOR BAX |
| Ensembl Family |
ENSFM00500000271520 |
| EMBL-Bank ID |
AJ417988, AK291076, AF250190, L22475, L22474, L22473, AF008195, AF008196, U19599, CH471177, BC014175, AY217036, AJ586909, AJ586910, AF339054, AF247393, AF007826 |
| UniProt Accession |
Q8WXU1, Q07812, Q9UEI8, Q5ZPJ1, Q5ZPJ0, O95074 |
| Ensembl Gene ID |
ENSG00000087088 |
| Ensembl Protein ID |
ENSP00000346461, ENSP00000389971, ENSP00000293288, ENSP00000263262, ENSP00000426184, ENSP00000426328, ENSP00000348871, ENSP00000375744, ENSP00000441413 |
| RefSeq ID |
NR_027882, NP_620118, NP_620119, NP_620116, NM_138764, NM_138763, NM_138761, NM_004324, NP_004315 |
| Description |
BCL2-associated X protein [Source:HGNC Symbol;Acc:959] |
| HGNC Symbol |
BAX |
| Entrez Gene ID |
581 |
| Ensembl Transcript ID |
ENST00000507757, ENST00000513217, ENST00000391871, ENST00000513545, ENST00000293288, ENST00000539787, ENST00000345358, ENST00000356483, ENST00000503726, ENST00000354470, ENST00000506183, ENST00000515540, ENST00000415969, ENST00000502487 |
| UniGene ID |
Hs.717082 |
| Design Element |
211833_s_at, ENST00000502487, ENST00000513545, ENST00000507757, 1997_s_at, ENST00000506183, 2066_at, ENST00000539787, 2067_f_at, 208478_s_at, ENST00000293288, ENST00000503726, ENST00000415969, ENST00000356483, 2065_s_at, ENST00000515540, ENST00000513217, ENST00000345358, ENST00000354470, 1998_i_at, g841237_3p_a_at, ENST00000391871 |
| Search EB-eye |
ENSG00000087088
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