ABCB1
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Homo sapiens |
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ABCB1 is differentially expressed in 283 experiments: 124 organism parts: liver, kidney, ... (122 more);, 184 disease states: normal, lung adenocarcinoma, ... (182 more);, 116 cell types 329 cell lines 25 compound treatments and 74 other conditions. |
| Synonyms |
PGY1, CD243, ABC20, GP170, P-gp, CLCS, MDR1 |
| Orthologs |
Abcb1a
(Rattus norvegicus)
E1BS63_CHICK
(Gallus gallus)
ENSBTAG00000015666
(Bos taurus)
Abcb1b
(Mus musculus)
B2M0T2_BOVIN
(Bos taurus)
F1NKZ1_CHICK
(Gallus gallus)
Abcb1b
(Rattus norvegicus)
Abcb1a
(Mus musculus)
CG10226
(Drosophila melanogaster)
Mdr50
(Drosophila melanogaster)
Mdr49
(Drosophila melanogaster)
Mdr65
(Drosophila melanogaster)
STE6
(Saccharomyces cerevisiae)
abcb1
(Xenopus laevis)
NP_001003215.1
(Canis familiaris)
(Compare orthologs)
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| Ensembl Family Description |
ATP BINDING CASSETTE SUB FAMILY B MEMBER P GLYCOPROTEIN |
| Gene Ontology Term |
transporter activity, transport, protein binding, nucleoside-triphosphatase activity, membrane, Golgi membrane, ATPase activity, membrane fraction, ATP binding, ATPase activity, coupled to transmembrane movement of substances, G2/M transition of mitotic cell cycle, nucleotide binding, response to drug, apical plasma membrane, integral to membrane, hydrolase activity, xenobiotic-transporting ATPase activity, transmembrane transport, cell surface, intercellular canaliculus, stem cell proliferation |
| Gene Ontology ID |
GO:0009986, GO:0016020, GO:0016021, GO:0016324, GO:0008559, GO:0042493, GO:0016887, GO:0016787, GO:0000086, GO:0042626, GO:0005624, GO:0005524, GO:0005515, GO:0055085, GO:0006810, GO:0005215, GO:0000166, GO:0000139, GO:0017111, GO:0046581, GO:0072089 |
| InterPro ID |
IPR017940, IPR001140, IPR003439, IPR003593, IPR019195 |
| InterPro Term |
ATPase_AAA+_core, ABC_transporter-like, ABC_transptr_TM_dom, ABC_transporter_type1, ABC_ATPase_put |
| Ensembl Family |
ENSFM00370000118589 |
| EMBL-Bank ID |
AC005068, EU852583, M29447, M29446, M29445, M29444, M29443, M29442, M29441, M29440, M29437, M29436, M29439, M29438, M29433, M29432, M29435, M29434, M29431, M29430, M29427, M29426, M29425, M29424, M29428, M29429, M14758, AF016535, EU854148, FJ158815, X58723, M37724, M37725, AY425005, AY425006, CH471091, AC002457, CH236949, AK290159, AY910577, HQ291700, HQ291703, HQ291704, HQ291701, HQ291707, HQ291708, HQ291705, HQ291706, HQ291709, HQ291710, HQ291712, HQ291713, HQ291714, HQ291715, HQ291716, HQ291717, HQ291718, HQ291719, HQ291724, HQ291723, HQ291722, HQ291721, HQ291720, HQ291727, HQ291728, HQ291725, HQ291726, HQ291734, HQ291733, HQ291736, HQ291735, HQ291730, HQ291732, HQ291731, HQ291737, HQ291738, HQ291739, HQ291743, HQ291744, HQ291741, HQ291740, HQ291742, HQ291747, HQ291748, HQ291745, HQ291746, HQ291749, HQ291753, HQ291754, HQ291755, HQ291756, HQ291757, HQ291758, HQ291750, HQ291751, HQ291752, HQ291765, HQ291763, HQ291762, HQ291764, HQ291760, HQ291761, HQ291640, HQ291643, HQ291641, HQ291642, HQ291649, HQ291648, HQ291644, HQ291646, HQ291631, HQ291639, HQ291638, HQ291637, HQ291635, HQ291633, HQ291632, HQ291628, HQ291621, HQ291620, HQ291623, HQ291625, HQ291618, HQ291619, HQ291616, HQ291617, HQ291611, HQ291610, HQ291615, HQ291614, HQ291613, HQ291609, HQ291608, HQ291605, HQ291604, HQ291607, HQ291606, HQ291600, HQ291602, HQ291603, HQ291697, HQ291696, HQ291698, HQ291688, HQ291689, HQ291685, HQ291686, HQ291687, HQ291683, HQ291684, HQ291694, HQ291693, HQ291692, HQ291691, HQ291690, HQ291677, HQ291678, HQ291679, HQ291671, HQ291673, HQ291675, HQ291680, HQ291682, HQ291681, HQ291668, HQ291661, HQ291662, HQ291666, HQ291667, HQ291664, HQ291663, HQ291670, HQ291656, HQ291657, HQ291658, HQ291651, HQ291653, HQ291652, HQ291654, HQ291655, HQ291578, HQ291577, HQ291576, HQ291575, HQ291574, HQ291579, HQ291580, HQ291581, HQ291584, HQ291582, HQ291583, HQ291569, HQ291570, HQ291571, HQ291572, HQ291573, HQ291599, HQ291588, HQ291586, HQ291587, HQ291589, HQ291594, HQ291595, HQ291596, HQ291598, HQ291597, HQ291590, HQ291592, HQ291593, HQ291702, HQ291711, HQ291729, HQ291645, HQ291647, HQ291630, HQ291636, HQ291634, HQ291629, HQ291622, HQ291624, HQ291627, HQ291626, HQ291612, HQ291601, HQ291695, HQ291699, HQ291676, HQ291672, HQ291674, HQ291669, HQ291660, HQ291665, HQ291659, HQ291650, HQ291585, HQ291591 |
| Ensembl Protein ID |
ENSP00000378156, ENSP00000265724, ENSP00000411075, ENSP00000399419, ENSP00000444095, ENSP00000437986 |
| RefSeq ID |
NM_000927, NP_000918 |
| UniProt Accession |
B5AK60, B5U2G4, Q6TBL4, P08183, A4D1D2, E7ENX5, E7EWT8, F4ZUT2, F4ZUQ5, F4ZUX9, F4ZUY5, F4ZUV4, F4ZUV0 |
| Ensembl Gene ID |
ENSG00000085563 |
| Description |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 [Source:HGNC Symbol;Acc:40] |
| HGNC Symbol |
ABCB1 |
| Gene-Disease Assocation |
COLCHICINE RESISTANCE, INFLAMMATORY BOWEL DISEASE 13; IBD13 |
| Entrez Gene ID |
5243 |
| UniGene ID |
Hs.489033 |
| Ensembl Transcript ID |
ENST00000543174, ENST00000476862, ENST00000543898, ENST00000482527, ENST00000475929, ENST00000488737, ENST00000265724, ENST00000496821, ENST00000483831, ENST00000416177, ENST00000415096, ENST00000394661, ENST00000491360 |
| Design Element |
ENST00000476862, M14758_at, ENST00000475929, 209993_at, g2353263_3p_at, ENST00000482527, 1575_at, ENST00000543174, ENST00000394661, ENST00000496821, X58723_at, ENST00000483831, g9961253_3p_s_at, ENST00000265724, 243951_at, ENST00000416177, ENST00000415096, 209994_s_at, Hs.129467.0.A1_3p_at, 60295_at, 1576_g_at, ENST00000491360, 1682_s_at, ENST00000488737, ENST00000543898 |
| Search EB-eye |
ENSG00000085563
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