MECOM
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Homo sapiens |
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MECOM is differentially expressed in 308 experiments: 176 organism parts: liver, lung, ... (174 more);, 217 disease states: normal, prostate carcinoma, ... (215 more);, 99 cell types 441 cell lines 37 compound treatments and 80 other conditions. |
| Synonyms |
MDS1-EVI1, PRDM3, EVI1, MDS1 |
| Orthologs |
mecom
(Danio rerio)
Mecom
(Rattus norvegicus)
MECOM
(Bos taurus)
Mecom
(Mus musculus)
MECOM
(Gallus gallus)
CG10348
(Drosophila melanogaster)
ham
(Drosophila melanogaster)
mecom
(Xenopus laevis)
MECOM
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0003676, GO:0003677, GO:0008270, GO:0003700, GO:0016607, GO:0009617, GO:0009791, GO:0042803, GO:0005622, GO:0005515, GO:0006915, GO:0005634, GO:0046329, GO:0043069, GO:0000118, GO:0051726, GO:0046872, GO:0042127, GO:0006351, GO:0045944, GO:0045892, GO:0045893, GO:0030154, GO:0060039, GO:0009605, GO:0006954, GO:0030900, GO:0001780, GO:0001701, GO:0071425, GO:0035115, GO:0035116 |
| InterPro Term |
Znf_C2H2-like, Znf_BED_prd, Znf_C2H2, SET_dom |
| Gene Ontology Term |
DNA binding, negative regulation of transcription, DNA-dependent, protein binding, nuclear speck, apoptosis, negative regulation of programmed cell death, histone deacetylase complex, regulation of cell proliferation, intracellular, transcription, DNA-dependent, metal ion binding, nucleic acid binding, cell differentiation, positive regulation of transcription from RNA polymerase II promoter, regulation of cell cycle, response to bacterium, nucleus, negative regulation of JNK cascade, post-embryonic development, protein homodimerization activity, positive regulation of transcription, DNA-dependent, zinc ion binding, in utero embryonic development, embryonic hindlimb morphogenesis, forebrain development, pericardium development, embryonic forelimb morphogenesis, response to external stimulus, inflammatory response, neutrophil homeostasis, hemopoietic stem cell proliferation, sequence-specific DNA binding transcription factor activity |
| InterPro ID |
IPR001214, IPR007087, IPR003656, IPR015880 |
| Ensembl Family Description |
MDS1 AND EVI1 COMPLEX LOCUS EVI1 ECOTROPIC VIRUS INTEGRATION SITE 1 |
| Ensembl Family |
ENSFM00570000851130 |
| Description |
MDS1 and EVI1 complex locus [Source:HGNC Symbol;Acc:3498] |
| EMBL-Bank ID |
AC074033, AF487423, AF487424, AC007849, BC031019, X54989, AC069220, BC130520, BC143952, BC143951, AC078985, AK292865, AC024099, CH471052, BX640908, BX647613, S69002, S82592, AF164157, AF164156, AF164154, AF164155, AK304098 |
| Ensembl Protein ID |
ENSP00000418046, ENSP00000418828, ENSP00000418689, ENSP00000394302, ENSP00000419995, ENSP00000419757, ENSP00000419770, ENSP00000417506, ENSP00000417299, ENSP00000419537, ENSP00000420072, ENSP00000420048, ENSP00000420466, ENSP00000417922, ENSP00000417899, ENSP00000376493, ENSP00000264674 |
| RefSeq ID |
NM_001163999, NM_005241, NP_001157472, NP_001157471, NM_001164000, NP_005232, NP_001098547, NP_001098548, NP_004982, NM_004991, NM_001105077, NM_001105078, NM_001205194, NP_001192123 |
| Entrez Gene ID |
2122 |
| UniGene ID |
Hs.165830, Hs.611391, Hs.659873 |
| Ensembl Gene ID |
ENSG00000085276 |
| HGNC Symbol |
MECOM |
| UniProt Accession |
Q9UBK3, Q8IU84, Q03112, D3DNP4, C9JU02, E7EQ57, E7EPY2, E7ERX0, E7EU48, E7EUL6, E9PGE9 |
| Ensembl Transcript ID |
ENST00000264674, ENST00000487503, ENST00000485957, ENST00000460814, ENST00000460890, ENST00000475754, ENST00000468789, ENST00000492586, ENST00000486748, ENST00000481315, ENST00000484519, ENST00000494292, ENST00000392736, ENST00000494597, ENST00000472280, ENST00000466623, ENST00000433243, ENST00000461430, ENST00000464456 |
| Design Element |
ENST00000475754, 226420_at, ENST00000487503, ENST00000481315, ENST00000433243, ENST00000468789, ENST00000486748, ENST00000494292, ENST00000392736, ENST00000461430, 208434_at, Hs.234773.0.S1_3p_at, 1882_g_at, 46205_at, g4826827_3p_at, ENST00000472280, ENST00000464456, 221884_at, ENST00000494597, Hs.234773.0.S2_3p_at, gnf1h02449_at, ENST00000460814, ENST00000485957, ENST00000460890, ENST00000484519, ENST00000466623, 31532_at, ENST00000264674, ENST00000492586, 1881_at, U43292_at, 59145_at |
| Search EB-eye |
ENSG00000085276
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