PHLPP1
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Homo sapiens |
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PHLPP1 is differentially expressed in 255 experiments: 129 organism parts: amygdala, spinal cord, ... (127 more);, 136 disease states: normal, glioblastoma, ... (134 more);, 84 cell types 378 cell lines 36 compound treatments and 61 other conditions. |
| Synonyms |
PHLPP, PLEKHE1, KIAA0606, SCOP |
| Orthologs |
PHLPP1
(Danio rerio)
PHLPP1
(Gallus gallus)
Phlpp1
(Mus musculus)
CYR1
(Saccharomyces cerevisiae)
Phlpp1
(Rattus norvegicus)
Phlpp
(Drosophila melanogaster)
phlpp1
(Xenopus laevis)
PHLPP1
(Bos taurus)
PHLPP1
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0048015, GO:0016020, GO:0003824, GO:0008543, GO:0007623, GO:0016787, GO:0004722, GO:0005515, GO:0006915, GO:0005737, GO:0005634, GO:0005829, GO:0046872, GO:0048011 |
| Gene Ontology Term |
cytosol, protein binding, apoptosis, cytoplasm, membrane, metal ion binding, protein serine/threonine phosphatase activity, fibroblast growth factor receptor signaling pathway, nucleus, hydrolase activity, circadian rhythm, catalytic activity, nerve growth factor receptor signaling pathway, phosphatidylinositol-mediated signaling |
| InterPro ID |
IPR001611, IPR001932, IPR001849, IPR003591 |
| InterPro Term |
Leu-rich_rpt_typical-subtyp, Pleckstrin_homology, Leu-rich_rpt, PP2C-like |
| Ensembl Family Description |
PH DOMAIN LEUCINE RICH REPEAT PHOSPHATASE 1 EC_3.1.3.16 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING FAMILY E MEMBER 1 PH DOMAIN CONTAINING FAMILY E MEMBER 1 SUPRACHIASMATIC NUCLEUS CIRCADIAN OSCILLATORY |
| Ensembl Family |
ENSFM00250000001904 |
| Description |
PH domain and leucine rich repeat protein phosphatase 1 [Source:HGNC Symbol;Acc:20610] |
| EMBL-Bank ID |
BC010706, AK001924, BC082244, BC014927, BC063519, AB011178, BC047653, AC022046, AC015989, AC027553, BC126277 |
| Entrez Gene ID |
23239 |
| Ensembl Protein ID |
ENSP00000383170, ENSP00000262719 |
| UniGene ID |
Hs.465337, Hs.714151 |
| HGNC Symbol |
PHLPP1 |
| RefSeq ID |
NP_919431, NM_194449 |
| Ensembl Gene ID |
ENSG00000081913 |
| UniProt Accession |
O60346 |
| Ensembl Transcript ID |
ENST00000262719, ENST00000487409, ENST00000497351, ENST00000400316 |
| Design Element |
ENST00000497351, ENST00000262719, gnf1h06689_s_at, 35719_at, ENST00000487409, ENST00000400316, 212719_at, Hs.38176.0.S1_3p_at |
| Search EB-eye |
ENSG00000081913
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