PAX2
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Homo sapiens |
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PAX2 is differentially expressed in 183 experiments: 98 organism parts: kidney, esophagus, ... (96 more);, 145 disease states: normal, breast carcinoma, ... (143 more);, 45 cell types 227 cell lines 19 compound treatments and 63 other conditions. |
| Orthologs |
Pax2
(Mus musculus)
F6WAV5_CIOIN
(Ciona intestinalis)
F1NEQ7_CHICK
(Gallus gallus)
F6VTG6_CIOIN
(Ciona intestinalis)
PAX2
(Bos taurus)
Pax2
(Rattus norvegicus)
sv
(Drosophila melanogaster)
ENSXETG00000014206
(Xenopus laevis)
PAX2
(Canis familiaris)
(Compare orthologs)
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| InterPro ID |
IPR001523, IPR022130 |
| Gene Ontology ID |
GO:0003677, GO:0007275, GO:0010001, GO:0048863, GO:0048854, GO:0007409, GO:0007501, GO:0007601, GO:0006916, GO:0005634, GO:0005815, GO:0043069, GO:0043066, GO:0043154, GO:0006355, GO:0006351, GO:0001709, GO:0006366, GO:0043234, GO:0045944, GO:0045892, GO:0045893, GO:0043491, GO:0016175, GO:0060231, GO:0072162, GO:0072179, GO:0072205, GO:0072207, GO:0072221, GO:0042472, GO:0003337, GO:0002072, GO:0003406, GO:0050679, GO:0090190, GO:0090103, GO:0090102, GO:0043010, GO:0032993, GO:0001823, GO:0001843, GO:0045918, GO:0044212, GO:0001658, GO:0001655, GO:0071300, GO:0071333, GO:0070301, GO:0021631, GO:0021554, GO:0034451, GO:0039003, GO:0048793, GO:2000594, GO:0072075, GO:0000987, GO:0072300, GO:0072305, GO:0072307, GO:0072108, GO:0072189, GO:0072289, GO:0072593, GO:0035566, GO:2000378, GO:2000597, GO:0061360, GO:0021633, GO:0021650, GO:0035799 |
| Gene Ontology Term |
DNA binding, negative regulation of transcription, DNA-dependent, negative regulation of programmed cell death, regulation of transcription, DNA-dependent, cell fate determination, stem cell differentiation, protein complex, transcription, DNA-dependent, visual perception, negative regulation of apoptosis, mesodermal cell fate specification, anti-apoptosis, transcription from RNA polymerase II promoter, glial cell differentiation, protein kinase B signaling cascade, positive regulation of transcription from RNA polymerase II promoter, microtubule organizing center, multicellular organismal development, nucleus, axonogenesis, brain morphogenesis, positive regulation of transcription, DNA-dependent, negative regulation of caspase activity, cellular response to retinoic acid, metanephric distal convoluted tubule development, cellular response to glucose stimulus, optic nerve morphogenesis, mesenchymal to epithelial transition involved in metanephros morphogenesis, urogenital system development, neural tube closure, optic nerve development, branching involved in ureteric bud morphogenesis, mesonephros development, negative regulation of cytolysis, optic cup morphogenesis involved in camera-type eye development, nephric duct formation, metanephric epithelium development, protein-DNA complex, positive regulation of epithelial cell proliferation, cochlea morphogenesis, positive regulation of branching involved in ureteric bud morphogenesis, cellular response to hydrogen peroxide, cochlea development, centriolar satellite, retinal pigment epithelium development, camera-type eye development, inner ear morphogenesis, mesenchymal to epithelial transition, metanephric mesenchymal cell differentiation, superoxide-generating NADPH oxidase activity, metanephric collecting duct development, pronephric field specification, pronephros development, core promoter proximal region sequence-specific DNA binding, positive regulation of metanephric DCT cell differentiation, negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis, metanephric nephron tubule formation, regulation of metanephros size, ureter development, positive regulation of metanephric glomerulus development, negative regulation of reactive oxygen species metabolic process, metanephric mesenchyme development, reactive oxygen species metabolic process, transcription regulatory region DNA binding, regulation of metanephric nephron tubule epithelial cell differentiation, positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis, ureter maturation, optic nerve structural organization, vestibulocochlear nerve formation, optic chiasma development, positive regulation of optic nerve formation |
| InterPro Term |
Paired_box_N, Pax2_C |
| Ensembl Family Description |
PAIRED BOX PAX |
| Ensembl Family |
ENSFM00440000236852 |
| Ensembl Protein ID |
ENSP00000355069, ENSP00000398652, ENSP00000347385, ENSP00000396259, ENSP00000359317, ENSP00000359319, ENSP00000452429, ENSP00000452489, ENSP00000452527, ENSP00000451482 |
| EMBL-Bank ID |
AY153483, M89470, AL589862, L09747, L09748, L09746, L25597, U45254, U45255, U45253, U45250, U45251, U45247, U45246, U45245, U45248, U45249, CH471066, AL138762 |
| UniGene ID |
Hs.606681, Hs.155644 |
| HGNC Symbol |
PAX2 |
| RefSeq ID |
NM_003987, NM_003988, NM_003989, NM_003990, NP_003979, NP_003978, NP_003980, NP_003981, NP_000269, NM_000278 |
| Description |
paired box 2 [Source:HGNC Symbol;Acc:8616] |
| UniProt Accession |
Q02962, Q5SZP1, Q6YFJ8 |
| Ensembl Gene ID |
ENSG00000075891 |
| Gene-Disease Assocation |
PAPILLORENAL SYNDROME |
| Entrez Gene ID |
5076 |
| Ensembl Transcript ID |
ENST00000556085, ENST00000554172, ENST00000554363, ENST00000370294, ENST00000370296, ENST00000553492, ENST00000427256, ENST00000361791, ENST00000483202, ENST00000428433, ENST00000355243 |
| Design Element |
38184_at, ENST00000361791, ENST00000556085, 38186_g_at, 38185_at, M89470_s_at, Hs.155644.0.S2_3p_at, U45255_s_at, ENST00000370294, ENST00000427256, ENST00000553492, ENST00000355243, 206229_x_at, ENST00000428433, ENST00000554172, ENST00000483202, ENST00000554363, g4557824_3p_a_at, 206228_at, ENST00000370296 |
| Search EB-eye |
ENSG00000075891
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