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TFRC Homo sapiens
TFRC is differentially expressed in 159 experiments [181 up/188 dn]: 32 organism parts: blood [0 up/4 dn], bone marrow [4 up/0 dn], ...; 40 disease states: normal [4 up/14 dn], glioblastoma [2 up/0 dn], ...; 41 cell types, 35 cell lines, 27 compound treatments and 22 other conditions.
Synonyms TFRC
Orthologs C35C5.11 (Caenorhabditis elegans)  VPS70 (Saccharomyces cerevisiae)  R57.1 (Caenorhabditis elegans)  Tfrc (Mus musculus)  (Compare orthologs)
InterPro Term Peptidase M28, Protease-associated PA, Transferrin receptor-like, dimerisation
GO Terms cellular iron ion homeostasis, coated pit, endocytosis, extracellular region, interspecies interaction between organisms
Uniprot P02786 
Search EB-eye ENSG00000072274
REST API
Expression Summary
294 factor values, click each to filter
Factor Value Factor Up/Down
Legend: - number of studies the gene is up/down in
Normal Disease state
14
4
None Compound treatment
4
3
Monocyte Cell type
4
1
Blood Organism part
4
Bone marrow Organism part
4
Peripheral blood Organism part
4
Epithelial cell Cell type
2
2
Pan troglodytes Organism
3
Homo sapiens Organism
1
2
Stromal cell Cell type
1
2
Caudate nucleus Organism part
2
FLAP Compound treatment
2
MK886 Compound treatment
2
Macaca mulatta Organism
2
HNRPA2B Compound treatment
2
Invasive ductal carcinoma Histology
2
N/a Test result
2
Glioblastoma Disease state
2
0 cm away from the tumor bound... Observation
2
Estrogen receptor 1 positive; ... Test result
2
Hydroxyurea Compound treatment
2
Liver Organism part
2
Caco-2 Cell line
2
BT-474 Cell line
2
Breast carcinoma Disease state
2
Not applicable Histology
2
Tonsil Organism part
2
Nocodazole Compound treatment
2
MCF-7 Cell line
2
Estrogen receptor 1 positive; ... Test result
2
HL-60 Cell line
2
ERalpha transfected Genotype
2
Primary Disease staging
2
Normal Histology
2
Estrogen receptor 1 positive; ... Test result
2
Control Compound treatment
1
1
Skeletal muscle Organism part
1
1
Uninfected Infection
1
1
Gastric cancer Disease state
1
1
MDA-MB-231 Cell line
1
1
Heat-killed HL60 cell lysate Infection
1
Circulating neutrophil Cell type
1
Alveolar space neutrophil Cell type
1
Glucocorticoid sensitive Phenotype
1
Pretreatment primary sample Clinical info
1
Lymphatic endothelial cell Cell type
1
Glucocorticoid resistant Phenotype
1
SW480 Cell line
1
SW620 Cell line
1
Dimethyl sulfoxide Compound treatment
1
CodeLink Labeling Protocol type
1
BT474 Cell line
1
SKBR3 Cell line
1
Fetal bovine serum in media Growth condition
1
T47D Cell line
1
Enzo Labeling Protocol type
1
Affymetrix Labeling Protocol type
1
Heat-killed Anaplasma phagocyt... Infection
1
MDA468 Cell line
1
Heregulin Compound treatment
1
Kaposi's sarcoma-associated he... Infection
1
Grade II Tumor grading
1
Inter-prandial lipid micelles ... Growth condition
1
ITS medium Growth condition
1
Postprandial lipid micelles in... Growth condition
1
ITS medium with albumin-bound ... Growth condition
1
Rapamycin Compound treatment
1
Methotrexate Compound treatment
1
Oligodendroglioma Disease state
1
Neutrophil Cell type
1
Acute radiation toxicity Clinical history
1
Endometrioid carcinoma Disease state
1
Grade IV Tumor grading
1
Cadmium chloride 2.5-hydrate Compound treatment
1
CD3+ CD4+ CD8- CD45RA+ CD62L+ Phenotype
1
Naive T cell Cell type
1
Malignant melanoma Disease state
1
10 ng/ml LPS in media Growth condition
1
Media only Growth condition
1
Teratozoospermia Disease state
1
Normospermic Disease state
1
Serum starvation + thymidine b... Growth condition
1
None Infection
1
Epidermal keratinocyte Cell type
1
SkinEthic keratinocyte Cell type
1
Bacterial endotoxin Compound treatment
1
Umbilical cord Organism part
1
Fetus Developmental stage
1
Adult Developmental stage
1
Frontal cortex, superior motor... Organism part
1
Stage I Disease staging
1
Synovial fluid Organism part
1
HPL1 Cell line
1
Baseline uninfected Disease state
1
Fetal liver Organism part
1
Infrared light Light
1
Spermatocyte Cell type
1
Vascular smooth muscle cell Cell type
1
Lipopolysaccharide Compound treatment
1
CD71+ early erythroid Cell type
1
Inferior parietal lobule Organism part
1
Jurkat Cell line
1
Stage II Disease staging
1
Organism_part Material type
1
Cell Material type
1
T47-D Cell line
1
Chondrocyte Cell type
1
Placenta Organism part
1
Kidney Organism part
1
Johnsen score count 2: Sertoli... Histology
1
Fibroblast Cell type
1
Metastatic Disease staging
1
Training set Population
1
Test set Population
1
Anaplasma phagocytophilum Infection
1
Serum starvation synchronizati... Growth condition
1
Interferon-gamma + lipopolysac... Compound treatment
1
M1 macrophage Cell type
1
Ultraviolet light Light
1
Mannitol Compound treatment
1
Benign nevi Disease state
1
KSHV latent infection Disease state
1
4OH-tamoxifen Compound treatment
1
CD34+ Cell type
1
Lymph node Organism part
1
MCF10A Cell line
1
Stimulated polymorphonuclear l... Cell type
1
Unstimulated polymorphonuclear... Cell type
1
HL60 cell lysate Infection
1
Normal Clinical history
1
Hypericin incubated, not irrad... Growth condition
1
Hypericin incubated, irradiate... Growth condition
1
HTERT/HPVE6/HPVE7/SV40t transf... Gene modification
1
TIVE Cell line
1
5-aza-2'-deoxycytidine + trich... Compound treatment
1
GLI72 Cell line
1
Appendix Organism part
1
Huntington's disease Disease state
1
Trichostatin A Compound treatment
1
TaN0M0 Disease staging
1
HTERT/HPVE6 transfection Gene modification
1
Acute malaria, natural infecti... Disease state
1
Endothelial cell + pericyte Cell type
1
Relapse 0; ER status ER+; brai... Clinical info
1
Testis Organism part
1
Atrial mycocardium Organism part
1
Ventricular myocardium Organism part
1
SKMEL5 Cell line
1
HTERT/HPVE6/HPVE7/SV40t/hRas t... Gene modification
1
Ischemic cardiomyopathy Disease state
1
Astrocyte Cell type
1
HeLa Cell line
1
White blood cell Cell type
1
Platelet Cell type
1
CD3- CD4+ CD8- Phenotype
1
Intrathymic T progenitor cell Cell type
1
MiR15a/miR16-1 transfection Gene modification
1
Ciliary ganglion Organism part
1
Burkitt's lymphoma Disease state
1
Dermal fibroblast Cell type
1
PC3 Cell line
1
ERbeta transfected Genotype
1
G3 Tumor grading
1
SNU1 Cell line
1
Stage IV/3 Disease staging
1
T3bN1M0 Disease staging
1
G1 Tumor grading
1
Primary gastric tumor Organism part
1
Normal Disease staging
1
Head and neck squamous cell ca... Disease state
1
AIDS-KS, HIV+, nodular (late) ... Disease state
1
Actinomycin D Compound treatment
1
Duodenum Organism part
1
CD4+ T cell Cell type
1
T4aN0M0 Disease staging
1
Pseudomonas aeruginosa Infection
1
Erythrocyte Cell type
1
Kaposi's sarcoma Disease state
1
Plasma cell Cell type
1
B lymphocyte Cell type
1
Skin substitute Cell type
1
Macrophage Cell type
1
ITV Cell line
1
Frontal cortex, primary motor ... Organism part
1
Seminiferous tubule Organism part
1
Waldenstrom's macroglobulinemi... Disease state
1
Term Developmental stage
1
Midgestation Developmental stage
1
Staphylococcus aureus Infection
1
BCKN-1 Cell line
1
GLI60 Cell line
1
T4aN2M1 Disease staging
1
BJAB Cell line
1
Pancreatic cancer Disease state
1
Obesity Disease state
1
Tumor Organism part
1
Effector memory CD4 T cell Target cell type
1
Cartilage Organism part
1
Control for EGF Compound treatment
1
CD4+ T-cell Cell type
1
Nickel(II) chloride hexahydrat... Compound treatment
1
Symptomatic Disease staging
1
Empty vector Gene modification
1
Total_RNA Material type
1
Polysome-associated RNA Material type
1
Diagnosed with skin cancer bef... Clinical history
1
Johnsen score count 10: full s... Histology
1
Relapse 1; ER status ER+; brai... Clinical info
1
CXCR5(hi)ICOS(hi) CD4 T cell Target cell type
1
Lung adenocarcinoma Disease state
1
Chronic lymphocytic leukemia Disease state
1
Female Sex
1
Male Sex
1
Cerebellum Organism part
1
Dendritic cell-derived osteocl... Cell type
1
Johnsen score count 3.2: Serto... Histology
1
Respiratory syncytial virus Infection
1
BC-1 Cell line
1
Uninfected control RNAi
1
Whole blood Organism part
1
Ethanol Vehicle
1
Estrogen receptor 1 positive; ... Test result
1
T84 Cell line
1
Cystic change Histology
1
IMP(1,3)A RNAi
1
Breast cancer Disease state
1
Multiple myeloma Disease state
1
ITM-E6E7-ST Cell line
1
Non-steroidal anti-inflammator... Compound treatment
1
No induction Protocol type
1
Sapphyrin PCI-2054 Compound treatment
1
IL-22 Compound treatment
1
GLI56 Cell line
1
Vasectomized Clinical history
1
Chronic myelogenous leukemia Disease state
1
SsMCF7 Cell line
1
Dendritic cell Cell type
1
None Gene modification
1
Cigarette smoke Compound treatment
1
HaCaT Cell line
1
Naive CD4 T cell Target cell type
1
Leishmania donovani Infection
1
U87 Cell line
1
U373 Cell line
1
Refractory anemia with ringed ... Clinical info
1
Cornea epithelium Organism part
1
Conjunctival epithelium Organism part
1
Gorilla gorilla Organism
1
Idiopathic dilated cardiomyopa... Disease state
1
Pan paniscus Organism
1
Control Phenotype
1
ERalpha L540Q transfected Genotype
1
Duchenne muscular dystrophy Disease state
1
MDS-associated acute myeloid l... Disease state
1
Acute myeloid leukemia Disease state
1
Plasmacytoid dendritic cell Cell type
1
Classic-KS, HIV-, nodular (lat... Disease state
1
Acute promyelocytic leukemia Disease state
1
Collagen/chondroitin tissue en... Growth condition
1
Tissue culture polystyrene dis... Growth condition
1
T4bN1M0 Disease staging
1
Intraepithelium Organism part
1
Native skin Cell type
1
Benign Disease staging
1
Acute lymphocytic leukemia Disease state
1
Polyarticular rheumatoid arthr... Disease state
1
CD11c+ dendritic cell Cell type
1
Colorectal cancer recurrence Disease state
1
Colorectal cancer recurrence-f... Disease state
1
AdERb high moi Gene modification
1
T cell Cell type
1
Peripheral blood mononuclear c... Cell type
1
Normal donor Clinical info
1
Growth medium Vehicle
1
Beas2B Cell line
1
T2N0M0 Disease staging
1
Acute rejection Clinical info
1
Measles virus Chicago-1 strain Infection
1
Psoriatic lesional biopsy Clinical info
1
Uninvolved biopsy Clinical info
1
CD8+ T cell Cell type
1
Spleen Organism part
1
Central memory 1 CD4 T cell Target cell type
1
Met5A Cell line
1
Senescence bypassed Phenotype
1
PDGF-A dominant-negative Genotype
1
Epilepsy Disease state
1
Astrocytic tumor Disease state
1
Refractory anemia with excess ... Clinical info
1
Monocyte-derived osteoclast Cell type
1
Sapphyrin PCI-2050 Compound treatment
1
Adenocarcinoma Disease state
1
Geriatric Developmental stage
1
Pediatric Developmental stage
1
Expression Profiles
E-GEOD-5824: Transcription profiling of human Acute Lymphoblastic Leukemia CEM_C1 cells treated with rapamycin identifies rapamycin as a glucocorticoid resistance reversal agent
Experimental Factors
Phenotype Time Clinical info Dose Compound treatment
Show expression profile  /  experiment details

 
E-GEOD-2405: Transcription profiling time course of the human polymorphonuclear leukocyte response to exposure to Anaplasma phagocytophilum or Staphylococcus aureus
Experimental Factors
Time Infection
Show expression profile  /  experiment details

 
E-GEOD-1725: Transcription profiling of human lymphoblastoid cells from patients with limited or acute radiation toxicity, skin cancer patients and normal controls, exposed to UV or IR light
Experimental Factors
Individual Light Clinical history
Show expression profile  /  experiment details

 
E-GEOD-2322: Transcription profiling of human neutrophils obtained after exposure endotoxin by bronchoscopic instillation reveals differential gene expression between air space and circulating neutrophils
Experimental Factors
Show expression profile  /  experiment details

 
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