TFRC
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Homo sapiens |
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TFRC is differentially expressed in 369 experiments: 131 organism parts: placenta, bone marrow, ... (129 more);, 233 disease states: normal, chronic myelogenous leukemia, ... (231 more);, 128 cell types 458 cell lines 40 compound treatments and 87 other conditions. |
| Synonyms |
TFR1, CD71 |
| Orthologs |
TFRC
(Gallus gallus)
tfr1a
(Danio rerio)
tfr1b
(Danio rerio)
TFRC (2 of 3)
(Danio rerio)
TFRC
(Bos taurus)
VPS70
(Saccharomyces cerevisiae)
Tfrc
(Mus musculus)
Tfrc
(Rattus norvegicus)
tfrc
(Xenopus laevis)
TFR1_CANFA
(Canis familiaris)
(Compare orthologs)
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| Gene Ontology ID |
GO:0008233, GO:0009986, GO:0016020, GO:0016023, GO:0005905, GO:0007584, GO:0007568, GO:0030544, GO:0051087, GO:0048471, GO:0005576, GO:0004872, GO:0006953, GO:0005739, GO:0006879, GO:0006897, GO:0005886, GO:0005887, GO:0005768, GO:0055085, GO:0006508, GO:0001666, GO:0046688, GO:0004998, GO:0010042, GO:0010039, GO:0010035, GO:0010033, GO:0042470, GO:0055038, GO:0032526, GO:0045780, GO:0044419, GO:0030316, GO:0033572, GO:0070062 |
| Gene Ontology Term |
plasma membrane, response to copper ion, Hsp70 protein binding, acute-phase response, membrane, peptidase activity, chaperone binding, extracellular region, response to hypoxia, response to nutrient, coated pit, integral to plasma membrane, aging, receptor activity, cytoplasmic membrane-bounded vesicle, endosome, perinuclear region of cytoplasm, proteolysis, cellular iron ion homeostasis, transmembrane transport, cell surface, mitochondrion, endocytosis, extracellular vesicular exosome, recycling endosome membrane, transferrin transport, response to iron ion, positive regulation of bone resorption, transferrin receptor activity, response to retinoic acid, response to inorganic substance, interspecies interaction between organisms, response to organic substance, response to manganese ion, melanosome, osteoclast differentiation |
| InterPro Term |
Peptidase_M28, Protease-assoc_domain, TFR-like_dimer_dom |
| InterPro ID |
IPR007484, IPR003137, IPR007365 |
| Ensembl Family |
ENSFM00500000270210 |
| Ensembl Family Description |
TRANSFERRIN RECEPTOR 1 TR TFR TFR1 TRFR CD71 ANTIGEN |
| Description |
transferrin receptor (p90, CD71) [Source:HGNC Symbol;Acc:11763] |
| UniProt Accession |
P02786, F5H6B1, F8WBE5 |
| EMBL-Bank ID |
BC001188, X01060, AF187320, AB209254, DQ496099, CH471191, M11507, AC024937 |
| RefSeq ID |
NM_003234, NP_003225, NP_001121620, NM_001128148 |
| Ensembl Protein ID |
ENSP00000414015, ENSP00000353224, ENSP00000390133, ENSP00000402839, ENSP00000376197, ENSP00000437753, ENSP00000443913 |
| Entrez Gene ID |
7037 |
| Ensembl Gene ID |
ENSG00000072274 |
| HGNC Symbol |
TFRC |
| UniGene ID |
Hs.529618 |
| Ensembl Transcript ID |
ENST00000360110, ENST00000482479, ENST00000465288, ENST00000463047, ENST00000463356, ENST00000477148, ENST00000420415, ENST00000483983, ENST00000540528, ENST00000392396, ENST00000421258, ENST00000535031, ENST00000464011, ENST00000464368, ENST00000491658, ENST00000475593, ENST00000426789 |
| Design Element |
ENST00000475593, 208691_at, X01060_at, ENST00000426789, ENST00000482479, ENST00000477148, ENST00000483983, ENST00000420415, 51674_at, AFFX-HUMTFRR/M11507_5_at, ENST00000463356, ENST00000463047, ENST00000535031, Hs.185726.0.A1_3p_at, 237215_s_at, 237214_at, g4507456_3p_a_at, AFFX-HUMTFRR/M11507_3_at, ENST00000360110, ENST00000540528, ENST00000491658, 37324_at, 207332_s_at, AFFX-HUMTFRR/M11507_M_at, ENST00000465288, ENST00000464368, ENST00000464011, ENST00000392396, ENST00000421258 |
| Search EB-eye |
ENSG00000072274
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